Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 24, Problem 11P
Interpretation Introduction

Interpretation:

The difference of heparin being helpful only when it is added on the onset of transcription process and is of no use if added after the transcription process starts should be explained.

Concept introduction:

Heparin is a polynomic polysaccharide − glycosaminoglycan and it is anionic due to the presence of sulphates. It helps in blocking the transcription process by initiating RNA polymerase enzyme by virtue of this binding with the double stranded DNA molecule.

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