Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 24, Problem 24.4CC
Both EGF (a mitogen) and TGFβ (when acting as an inhibitor) affect Cdk-cyclin complex function. Compare and contrast the ways in which EGF and TGFβ operate. What would happen if a cell were exposed to both at the same time?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
The expression patterns as well as activation of different types of CDKs happen at different stages of the cell cycle. Explain why.
Why doesn't Cdk1 active immediately upon binding to cyclin B? What other components of the cell’s regulatory machinery could explain the delay in activation of the kinase activity?
''In the cellular regulatory pathways that controlcell growth and proliferation, the products of oncogenesare stimulatory components and the products of tumorsuppressor genes are inhibitory components.'' 'Is this statement true? Explain why or why not.
Chapter 24 Solutions
Becker's World of the Cell (9th Edition)
Ch. 24 - Prob. 1QCh. 24 - Which DNA sequences are more alike: a pair of...Ch. 24 - Suppose you treat rapidly dividing tissue culture...Ch. 24 - Cyclin D is part of the G1 Cdk-cyclin complex....Ch. 24 - Both EGF (a mitogen) and TGF (when acting as an...Ch. 24 - A knockout mouse has been produced using the...Ch. 24 - Cell Cycle Phases. Indicate whether each of the...Ch. 24 - QUANTITATIVE The Mitotic Index and the Cell Cycle....Ch. 24 - Chromosome Movement in Mitosis. It is possible to...Ch. 24 - Cytokinesis. Predict what will happen in each of...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- APC is a ubiquitin ligase activated by M-cyclin Cdk What is the function of APC when bound to Cdc20? What is the function of APC when bound to Cdh1?arrow_forwardDescribe the roles of p53 and NFAT and their nuclear import. How does the phosphorylation regulate the nuclear import/export of Pho4? Propose an experiment to test this mechanismarrow_forwardWhat inhibit CDK activity by bindingdirectly to the cyclin-CDK complex.arrow_forward
- The output of RTK pathways is often the activation of MAP Kinase. Explain how MAPK can lead to activation of a specific subset of proteins, leading to distinct effects in different cell types in response to the same growth signal.arrow_forwardMutations that inactivate p53 have a recessive phenotype, whereas mutations affecting Ras are dominant. Explain the difference.arrow_forwardMPF plays an important role during the regulation of the cell cycle. give examples that will support this statement.arrow_forward
- A second hit might occur through epigenetic alterations. In the promoter of RB1, there is a CpG island. Knowing this, how might you predict that a cell could epigenetically inactivate RB1 transcription?arrow_forwarda.What would happen if IKKbeta did not phosphorylate IkappaB? b.Why is it so hard to make cytokine therapies? c.Why would you use the MyD88 independent pathway versus the MyD88 dependent pathway?arrow_forward"given the numerous processes inside cells that are regulated by changes in Ca+2 concentration, it seems likely that Ca¹²-dependent cell-cell adhesions are also regulated by changes in Ca2 concentration" is true or false.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
The Cell Cycle and its Regulation; Author: Professor Dave Explains;https://www.youtube.com/watch?v=eqJqhA8HSJ0;License: Standard YouTube License, CC-BY
Cell Division - Mitosis and Meiosis - GCSE Biology (9-1); Author: Mr Exham Biology;https://www.youtube.com/watch?v=w7vp_uRA8kw;License: Standard YouTube License, CC-BY