Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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Chapter 26, Problem 7U

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Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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Given is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’ a. What is the complementary strand? b.Deduce the mRNA in this coding region. c.What is the amino acid sequence based on this mRNA? d. A very important mutation in human hemoglobin occurs in this DNA sequence, where the T at nucleotide 20 is replace with an A. The mutant hemoglobin is called sickle cell hemoglobin and is associated with severe anemia. What is the amino acid replacement that results in sickle-cell hemoglobin?

Given is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’a. What is the complementary strand?b. Deduce the mRNA in this coding region.c. What is the amino acid sequence based on this mRNA?d. A very important mutation in human hemoglobin occurs in this DNA sequence, where the T at nucleotide 20 is replace with an A. The mutant hemoglobin is called sickle cell hemoglobin and is associated with severe anemia. What is the amino acid replacement that results in sickle-cell hemoglobin?

Once translated into proteins: (a) How many nucleotides are there? (b) How many codons are there? (c) How many amino acids?

Answer 2

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Chapter 26, Problem 7U

Summary Introduction

Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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Answer 3

Question

Chapter 26, Problem 7U

Summary Introduction

Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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Answer 4

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Chapter 26, Problem 7U

Summary Introduction

Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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Answer 5

Chapter 26, Problem 7U

Summary Introduction

Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

Answer 6

Chapter 26, Problem 7U

Summary Introduction

Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

Answer 7

Chapter 26, Problem 7U

Summary Introduction

Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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Answer 11

Ch. 26.1 - Prob. 1LO Ch. 26.1 - Prob. 2LO Ch. 26.2 - Prob. 1LO Ch. 26.2 - Prob. 2LO Ch. 26.3 - Prob. 1LO Ch. 26.3 - Describe how viruses can contribute DNA to their...Ch. 26.4 - Describe the differences between acute and...Ch. 26.4 - Prob. 2LO Ch. 26.4 - Prob. 3LO Ch. 26.5 - Prob. 1LO

Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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Introduction: Prions are the proteinaceous infectious particles that lack nucleic acids. They possess misfolded proteins that can transmit their misfolded shape onto the normal variants of the same proteins. They cause several fatal and transmissible neurodegenerative diseases in animals and humans.

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