The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

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Answer 1

Question

Chapter 27, Problem 27.50P

(a)

Interpretation Introduction

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

(b)

Interpretation Introduction

Interpretation:

When bovine insulin is treated with Sanger’s reagent followed by hydrolysis of all peptide bonds, two labelled amino acids Glycine and Phenylalanine are detected. From this information, the conclusion drawn from the primary structure of bovine insulin has to be given.

Concept Introduction:

Sanger’s reagent reacts with the N-terminal amino group of polypeptides and forms the aromatic substitution at the N-terminal. On hydrolysis, the N-terminal amino acid is removed from the peptide chain.

(c)

Interpretation Introduction

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

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Answer 2

Question

Chapter 27, Problem 27.50P

(a)

Interpretation Introduction

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

(b)

Interpretation Introduction

Interpretation:

When bovine insulin is treated with Sanger’s reagent followed by hydrolysis of all peptide bonds, two labelled amino acids Glycine and Phenylalanine are detected. From this information, the conclusion drawn from the primary structure of bovine insulin has to be given.

Concept Introduction:

Sanger’s reagent reacts with the N-terminal amino group of polypeptides and forms the aromatic substitution at the N-terminal. On hydrolysis, the N-terminal amino acid is removed from the peptide chain.

(c)

Interpretation Introduction

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

Expert Solution & Answer

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Answer 3

Question

Chapter 27, Problem 27.50P

(a)

Interpretation Introduction

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

(b)

Interpretation Introduction

Interpretation:

When bovine insulin is treated with Sanger’s reagent followed by hydrolysis of all peptide bonds, two labelled amino acids Glycine and Phenylalanine are detected. From this information, the conclusion drawn from the primary structure of bovine insulin has to be given.

Concept Introduction:

Sanger’s reagent reacts with the N-terminal amino group of polypeptides and forms the aromatic substitution at the N-terminal. On hydrolysis, the N-terminal amino acid is removed from the peptide chain.

(c)

Interpretation Introduction

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

Expert Solution & Answer

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Answer 4

Question

Chapter 27, Problem 27.50P

(a)

Interpretation Introduction

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

(b)

Interpretation Introduction

Interpretation:

When bovine insulin is treated with Sanger’s reagent followed by hydrolysis of all peptide bonds, two labelled amino acids Glycine and Phenylalanine are detected. From this information, the conclusion drawn from the primary structure of bovine insulin has to be given.

Concept Introduction:

Sanger’s reagent reacts with the N-terminal amino group of polypeptides and forms the aromatic substitution at the N-terminal. On hydrolysis, the N-terminal amino acid is removed from the peptide chain.

(c)

Interpretation Introduction

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

Expert Solution & Answer

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Answer 5

Chapter 27, Problem 27.50P

(a)

Interpretation Introduction

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

(b)

Interpretation Introduction

Interpretation:

When bovine insulin is treated with Sanger’s reagent followed by hydrolysis of all peptide bonds, two labelled amino acids Glycine and Phenylalanine are detected. From this information, the conclusion drawn from the primary structure of bovine insulin has to be given.

Concept Introduction:

Sanger’s reagent reacts with the N-terminal amino group of polypeptides and forms the aromatic substitution at the N-terminal. On hydrolysis, the N-terminal amino acid is removed from the peptide chain.

(c)

Interpretation Introduction

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

Answer 6

Chapter 27, Problem 27.50P

(a)

Interpretation Introduction

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

Answer 7

Chapter 27, Problem 27.50P

(a)

Interpretation Introduction

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

Answer 8

(b)

Interpretation Introduction

Interpretation:

When bovine insulin is treated with Sanger’s reagent followed by hydrolysis of all peptide bonds, two labelled amino acids Glycine and Phenylalanine are detected. From this information, the conclusion drawn from the primary structure of bovine insulin has to be given.

Concept Introduction:

Sanger’s reagent reacts with the N-terminal amino group of polypeptides and forms the aromatic substitution at the N-terminal. On hydrolysis, the N-terminal amino acid is removed from the peptide chain.

Answer 9

(b)

Interpretation Introduction

Interpretation:

When bovine insulin is treated with Sanger’s reagent followed by hydrolysis of all peptide bonds, two labelled amino acids Glycine and Phenylalanine are detected. From this information, the conclusion drawn from the primary structure of bovine insulin has to be given.

Concept Introduction:

Sanger’s reagent reacts with the N-terminal amino group of polypeptides and forms the aromatic substitution at the N-terminal. On hydrolysis, the N-terminal amino acid is removed from the peptide chain.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

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Answer 15

Ch. 27.1 - Of the 20 protein-derived amino acids shown in...Ch. 27.2 - Prob. 27.2P Ch. 27.2 - Prob. 27.3P Ch. 27.3 - Draw a structural formula for Lys-Phe-Ala. Label...Ch. 27.4 - Which of these tripeptides are hydrolyzed by...Ch. 27.4 - Deduce the amino acid sequence of an undecapeptide...Ch. 27.6 - Prob. 27.7P Ch. 27 - What amino acid does each abbreviation stand for?...Ch. 27 - The configuration of the chiral center in -amino...Ch. 27 - Assign an R or S configuration to the chiral...

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

Solution Summary: The author explains the structural formula for the product formed by the treatment of N-terminal amino group with Sanger's reagent.

Concept explainers

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

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Chapter 27 Solutions

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

Solution Summary: The author explains the structural formula for the product formed by the treatment of N-terminal amino group with Sanger's reagent.

Concept explainers

Interpretation: The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

Interpretation: The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.

Want to see the full answer?

Chapter 27 Solutions

Interpretation:

The structural formula for the product formed by the treatment of N-terminal amino group with Sanger’s reagent has to be written and the mechanism of the product formation has to be explained.

Interpretation:

The structural information obtained by Sanger’s reagent and by Edman degradation has to be compared and contrasted.