The dependence of the sedimentation coefficient (s) of a spherical protein on its mass should be determined. The rate of sedimentation of 80-kDa protein than 40-kDa protein should be determined. Concept introduction: The sedimentation coefficient can be defined as a quantity associated with the microscopic particle size. It is equal to the particle’s terminal external velocity. It occurs when intermediate is centrifuged in a fluid divided by the centrifugal force acting on it. It is represented in units of time.

Question

Shape and dimension. (a) Tropomyosin, a 70-kDa muscle protein, is a two-stranded α-helical coiled coil. Estimate the length of the molecule. (b) Suppose that a 40-residue segment of a protein folds into a two-stranded antiparallel β structure with a 4-residue hairpin turn. What is the longest dimension of this motif?

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Question

Chapter 3, Problem 8P

Interpretation Introduction

Interpretation:

The dependence of the sedimentation coefficient (s) of a spherical protein on its mass should be determined. The rate of sedimentation of 80-kDa protein than 40-kDa protein should be determined.

Concept introduction:

The sedimentation coefficient can be defined as a quantity associated with the microscopic particle size. It is equal to the particle’s terminal external velocity. It occurs when intermediate is centrifuged in a fluid divided by the centrifugal force acting on it. It is represented in units of time.

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Shape and dimension. (a) Tropomyosin, a 70-kDa muscle protein, is a two-stranded α-helical coiled coil. Estimate the length of the molecule. (b) Suppose that a 40-residue segment of a protein folds into a two-stranded antiparallel β structure with a 4-residue hairpin turn. What is the longest dimension of this motif?

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