Pearson eText Biology: Life on Earth with Physiology -- Instant Access (Pearson+)
Pearson eText Biology: Life on Earth with Physiology -- Instant Access (Pearson+)
12th Edition
ISBN: 9780135755785
Author: Gerald Audesirk, Teresa Audesirk
Publisher: PEARSON+
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Chapter 3.4, Problem 1CSC

Infectious prions such as those that cause mad cow disease are abnormally folded versions of a protein that is found throughout the body. The secondary structure of the normal prion protein is primarily helical. Infectious prions, however, fold into pleated sheets. The pleated sheets are so stable they are unaffected by the enzymes that break down normal prion protein. As a result, infectious prions accumulate destructively in the brain.

Helices and pleated sheets are the two major secondary structures of proteins. What do protein tertiary and Quaternary structures look like?

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There are different types of helical structures that can be found in proteins (i.e., not only helices). What is common among different types of helices is that the he structure is maintained by intrachain hydrogen bonding between two polypeptide backbone atoms. Oftentimes, at least two intrachain hydrogen bonds need to be formed in order for a helix to start gaining stability. This can be observed from circular dichroism, technique that detects helicity in proteins. Circular dichroism starts detecting helicity in a helical chain only when there are at least two intrachain hydrogen bond formed. If a helical structure is too short such that it only has one intrachain hydrogen bond, the helix is too unstable for the helicity to be accurately detected th circular dichroism. Four different types of helical structures were studied using circular dichroism and the minimum number of residues needed for helicity to become detectable wa determined as summarized in the table below. Minimum number…
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Chapter 3 Solutions

Pearson eText Biology: Life on Earth with Physiology -- Instant Access (Pearson+)

Ch. 3.4 - Why do many proteins, when heated excessively....Ch. 3.4 - Why a Perm Is (Temporarily) Permanent?Ch. 3.4 - describe protein subunits and how proteins are...Ch. 3.4 - explain the four levels of protein structure and...Ch. 3.4 - list several functions of proteins and provide...Ch. 3.4 - Prob. 4CYLCh. 3.5 - describe the general structure of nucleotides?Ch. 3.5 - list three different functions of nucleotides?Ch. 3.5 - explain how nucleic acids are synthesized?Ch. 3.5 - give two examples of nucleic acids and their...Ch. 3.5 - Puzzling Proteins All cells use DNA as a blueprint...Ch. 3.6 - What kind of reaction breaks this molecule apart?Ch. 3.6 - An obese 55-year-old woman consults her physician...Ch. 3.6 - Why are steroid hormones able to diffuse through...Ch. 3.6 - compare and contrast the structure and synthesis...Ch. 3.6 - describe the functions of fats, oils, and waxes?Ch. 3.6 - Prob. 3CYLCh. 3.6 - Prob. 1CTCh. 3 - Polar molecules a. dissolve in lipids. b. are...Ch. 3 - Prob. 2MCCh. 3 - Prob. 3MCCh. 3 - Which of the following is not composed of...Ch. 3 - Prob. 5MCCh. 3 - In organic molecules made of chains of subunits,...Ch. 3 - Prob. 2FIBCh. 3 - Prob. 3FIBCh. 3 - Prob. 4FIBCh. 3 - Fill in the following with the appropriate type of...Ch. 3 - Prob. 1RQCh. 3 - List the four principal classes of biological...Ch. 3 - Prob. 3RQCh. 3 - Prob. 4RQCh. 3 - Prob. 5RQCh. 3 - Describe the synthesis of a protein from amino...Ch. 3 - Where in nature do we find cellulose? Where do we...Ch. 3 - Based on their structure, sketch and explain how...Ch. 3 - Prob. 2ACCh. 3 - Prob. 3AC
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