CAMPBELL BIOLOGY IN FOCUS (LL)-W/MOD.MA
CAMPBELL BIOLOGY IN FOCUS (LL)-W/MOD.MA
3rd Edition
ISBN: 9780135686065
Author: Urry
Publisher: PEARSON
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Chapter 35, Problem 8TYU
Summary Introduction

To determine:

The feasibility of treating septic shock with the drug that blocks the TLR signaling using mutated mice that has mutation that cause the inactivation of the TLR gene and purified LPS.

Introduction:

TLR are the toll like receptors that are involved in the septic shock of the body that is induced by the lipopolysaccharides (LPS) of the gram negative bacteria when it is introduced into the blood. The TLR are the reason for the septic shock.

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SCIENTIFIC INQUIRY A major cause of septic shock is thepresence of lipopolysaccharide (LPS) from bacteria in the blood.Suppose you have available purified LPS and several strains ofmice, each with a mutation that inactivates a particular TLRgene. How might you use these mice to test the feasibility oftreating septic shock with a drug that blocks TLR signaling?
a major cause of septic shock is the presence of lipopolysaccharide (LPS) from bacteria in the blood. suppose you have available purified LPS and several strain of mice, each with a mutation that inactivates a particular TLR gene. How might you use these mice to test the feasibility of treating septic shock with a drug that blocks TLR signaling?
Killer T-cells help protect us from viral infections. Explain the mechanism of their action.
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