To determine:
How does cyclosporine prevent rejection of transplanted organs.
Introduction:
Cyclosporine drugs are given to the patient who undergoes organ transplantation. Cyclosporine is responsible for the inhibition of cytokine secretion which stimulates helper T cell to divide and proliferate to induce an immune response against nonself cells.
To hypothesize:
A hypothesis to explain the phenomenon that why patients who received cyclosporine following transplants develop various kinds of cancers many years later.
Introduction:
To reduce the risk of organ transplant failure cyclosporine drugs are given to the patient who undergoes organ transplantation. It inhibits cytokine secretion which is responsible for the stimulation of immune response. But after many years these patients develop cancers.
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Biology: Life on Earth with Physiology Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)
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