Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 4, Problem 11P
In the rats identified in Problem
a.
b.
c.
d.
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When a white guinea pig is crossed to a yellow guinea pig, all the progeny are cream-colored. From a cross of two such F1’s, the F2 showed 32 white, 66 cream, and 30 yellow guinea pigs.
How is this trait inherited? _______________
Identify the genotype of the white guinea pig. ________
Identify the genotype of the yellow guinea pig. ________
Identify the genotype of the cream-colored guinea pig. ________
Identify the genotypes and the corresponding phenotypes of the F2 progeny.
Give the genotypic ratio. __________________
Give the phenotypic ratio. ___________________
Pigment in mouse fur is only produced when the C allele is present. Individuals of the cc genotype are white. If color is present, it may be determined by the A, a AA or Aa results in agouti color, while aa results in black coats.
What F1 and F2 genotypic and phenotypic ratios are obtained from a cross between AACC and aacc mice? (F2: intercross between F1 offspring)
Explain briefly the pattern of inheritance in this problem set and how you determined the phenotypic ratios in the offspring.
In crosses between mutant mice, you find the following patterns in the genotype for the A locus containing alleles A1, A2, A3 and A4:
What would be the best explanation for the inheritance and why?
Chapter 4 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 4 - 1. Define and distinguish incomplete penetrance...Ch. 4 -
2. Define and distinguish epistasis and...Ch. 4 - When working on barley plants, two researchers...Ch. 4 - Fifteen bacterial colonies growing on a complete...Ch. 4 - 5. In a type of parakeet known as a “budgie,”...Ch. 4 - 6. The and blood groups are given below for four...Ch. 4 - The wild-type color of horned beetles is black,...Ch. 4 - 8. Two genes interact to produce various...Ch. 4 - Prob. 9PCh. 4 - 10. In rats, gene produces black coat color if the...
Ch. 4 - 11. In the rats identified in Problem, a third...Ch. 4 - Using the information provided in Problems 10 and...Ch. 4 - 13. Total cholesterol in blood is reported as the...Ch. 4 - 14. Flower color in snapdragons results from the...Ch. 4 - 5. A plant line with reduced fertility comes to...Ch. 4 - Prob. 16PCh. 4 - The coat color in mink is controlled by two...Ch. 4 - Prob. 18PCh. 4 - 19. Feather color in parakeets is produced by the...Ch. 4 - Brachydactyly type D is a human autosomal dominant...Ch. 4 - 21. A male and a female mouse are each from...Ch. 4 - Xerodermapigmentosum (XP) is an autosomal...Ch. 4 - 23. Three strains of green-seeded lentil plants...Ch. 4 - Blue flower color is produced in a species of...Ch. 4 - 25. The following crosses are performed between...Ch. 4 - Two pure-breeding strains of summer squash...Ch. 4 - Marfan syndrome is an autosomal dominant disorder...Ch. 4 - 28. Yeast are single-celled eukaryotic organisms...Ch. 4 - Prob. 29PCh. 4 - Dr. Ara B. Dopsis and Dr. C. Ellie Gans are...Ch. 4 - Human ABO blood type is determined by three...Ch. 4 - In rabbits, albinism is an autosomal recessive...Ch. 4 - Dr. O. Sophila, a close friend of Dr. Ara B....Ch. 4 - In a breed of domestic cattle, horns can appear on...
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- The following pedigree shows the pattern of inheritance of red-green color blindness in a family. Females are shown as circles and males as squares; the squares or circles of individuals affected by the trait are filled in black. What is the chance that a son of the third-generation female indicated by the arrow will be color blind if the father is not color blind? If he is color blind?arrow_forwardIndividuals of genotype AaBb were mated to individuals of genotype aabb. One thousand offspring were counted, with the following results: 474 Aabb, 480 aaBb, 20 AaBb, and 26 aabb. What type of cross is it? Are these loci linked? What are the two parental classes and the two recombinant classes of offspring? What is the percentage of recombination between these two loci? How many map units apart are they?arrow_forwardIn dogs, dark coat color is dominant over albino, andshort hair is dominant over long hair. Assume that theseeffects are caused by two independently assorting genes.Seven crosses were done as shown below, in which D andA stand for the dark and albino phenotypes, respectively,and S and L stand for the short-hair and long-hairphenotypes.Number of progenyParental phenotypes D, S D, L A, S A, La. D, S × D, S 88 31 29 12b. D, S × D, L 19 18 0 0c. D, S × A, S 21 0 20 0d. A, S × A, S 0 0 29 9e. D, L × D, L 0 31 0 11f. D, S × D, S 45 16 0 0g. D, S × D, L 31 30 10 10Write the genotypes of the parents in each cross. Use thesymbols C and c for the dark and albino coat-color allelesand the symbols H and h for the short-hair and long-hairalleles, respectively. Assume parents are homozygousunless there is evidence otherwise.arrow_forward
- The Labrador Retriever’s coat colours are black, yellow, and chocolate.Yellow is produced by the presence of a recessive epistatic gene, which has the effect of masking the black and chocolate colour genes. Black (B) is dominant to chocolate (b).Therefore, the possible genotypes and corresponding phenotypes are: Phenotype Possible Genotypes Black G__B__ Brown G__bb Yellow gg__ Predict the percentage of offspring that would be black in colour for each of the following crosses. Record your answer as a whole number. Cross: GgBbGgBB GGBbGGBb Percentage ofOffspring: Answer% Answer%arrow_forwardIn mice, the wild-type coat color, agouti (AA) [left mouse], is dominant to solid-colored, black fur (aa) [middle mouse]. However, a separate gene (C) is necessary for pigment production. A mouse that is homozygous for a recessive c allele at this locus is unable to produce pigment and is albino [right mouse] regardless of the allele present at locus A. Thus, the following genotypes are listed with their associated phenotypes: ~ A/A; C/C or A/A; C/c or A/a; C/C or A/a; C/c ==> "agouti" ~ a/a; C/C or a/a; C/c ==> "black" ~ A/A; c/c or A/a; c/c or a/a; c/c or a/a; c/c ==> "albino" This is an example of recessive epistasis, in which the recessive c allele "stands upon" the possible genotypes for the A gene (A/A, A/a, or a/a). If two agouti mice with the A/a; C/c genotype are mated, what is the expected phenotypic ratio in their offspring? A.9 albino, 4 agouti, 3 black B. 9 agouti, 4 albino, 3 black C.9 black, 4 albino, 3 agouti D.9 agouti, 4 black, 3 albinoarrow_forwardIn a population of rabbits, you find three differentcoat color phenotypes: chinchilla (C), himalaya (H),and albino (A). To understand the inheritance of coatcolors, you cross individual rabbits with each otherand note the results in the following table.Cross number Parental phenotypes Phenotypes of progeny1 H × H 3/4 H : 1/4 A2 H × A 1/2 H : 1/2 A3 C × C 3/4 C : 1/4 H4 C × H all C5 C × C 3/4 C : 1/4 A6 H × A all H7 C × A 1/2 C : 1/2 A8 A × A all A9 C × H 1/2 C : 1/2 H10 C × H 1/2 C : 1/4 H : 1/4 Aa. What can you conclude about the inheritance ofcoat color in this population of rabbits?b. Ascribe genotypes to the parents in each of the10 crosses.c. What kinds of progeny would you expect, and inwhat proportions, if you crossed the chinchilla parents in crosses 9 and 10?arrow_forward
- In tomatoes, tall (D) is dominant over dwarf (d) and smooth fruit (P) is dominant over pubescent fruit (p), which is covered with fine hairs. A farmer has two tall and smooth tomato plants, which we will call plant A and plant B. The farmer crosses plants A and B with the same dwarf and pubescent plant and obtains the following numbers of progeny: Q. Explain why different proportions of progeny are produced when plant A and plant B are crossed with the same dwarf pubescent plant.arrow_forwardIn barley, a self-fertilizing species that can be cross-fertilized, two true-breeding strains with virescent leaves occur. In strain A, the trait is caused by a cytoplasmic gene while in strain B it is by a recessive chromosomal gene. What phenotypes would you expect among the progeny, and in what proportions in each of the following? Illustrate your crosses below, indicate and the female and male parent for each cross, and write the phenotype of all the parents and offspring(s). a. reciprocal crosses between A and Bb. crossing of each F1 in (a) to each of the paternal strainsc. self-fertilization of the F1’s in (a)d. reciprocal crosses between F1’s in (a) Use the following gene assignments: Strain A (trait is in Cytoplasm) A – virescent a – not virescent Strain B (recessive chromosomal gene) B – not virescent b - virescentarrow_forwardAmong dogs, short hair is dominant to long hair and dark coat color is dominant to white (albino) coat color. Assume that these two coat traits are caused by independently segregating gene pairs. For each of the crosses given below, write the most probable genotype (or genotypes if more than one answer is possible) for the parents. It is important that you select a realistic symbol set and define each symbol below. Assume that for cross (d), you were interested in determining whether fur color follows a 3:1 ratio. Set up (but do not complete the calculations) a Chi-square test for these data [fur color in cross (d)].arrow_forward
- . What is the probability of producing a child that willphenotypically resemble either one of the two parentsin the following four crosses? How many phenotypically different kinds of progeny could potentiallyresult from each of the four crosses?a. Aa Bb Cc Dd × aa bb cc ddb. aa bb cc dd × AA BB CC DDc. Aa Bb Cc Dd × Aa Bb Cc Ddd. aa bb cc dd × aa bb cc ddarrow_forwardA series of three-point testcrosses is made to determine the genetic map order of seven linked allele pairs: A/a, B/b, G/g, H/h, Q/q, R/r, and Y/y.From each cross between a triply heterozygous parent listed below, two recombinant classes were noticed as the least frequent among all 8 progeny classes, and are listed at the right in the table. A. For each testcross write the genotype of the F1 heterozygous parent. F1 Parental Phenotype Least frequent F2 Phenotype 1.AHB&ahb AHb & ahB 2.RYh&ryH RYH & ryh 3.BhY&bHy Bhy & bHY 4.qYB&Qyb qYb & QyB 5.AbQ&aBq Abq & aBQ 6.ghR&GHr ghr & GHR B. Write the unified map order of these genes, showing your reasoning.arrow_forwardPLEASE SHOW THE CROSSES USING PROBABILITY RULE In guinea pigs, rough coat (R) is dominant over smooth (r), and black coat (B) is dominant over white (b). If a pure-breeding rough, black animal is crossed with a smooth white one: What will be the appearance of the F1 progeny? The F2?arrow_forward
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