CASE STUDY | But he isn't deaf Researching their family histories, a deaf couple learns that each of them has relatives through several generations who are deaf. With a rudimentary understanding of genetics, they also learn that one of many forms of deafness can be inherited as an autosomal recessive trait. They plan to have children, and based on the above information, they are concerned that some or all of their children may be deaf. To their delight, their first child has normalhearing. The couple turns to you as a geneticist to help explain this situation. Is it likely that these parents inherited their deafness as an autosomal recessive trait?

Question

Want to see more full solutions like this?

Answer 1

Textbook Question

Chapter 4, Problem 1CS

CASE STUDY | But he isn't deaf

Researching their family histories, a deaf couple learns that each of them has relatives through several generations who are deaf. With a rudimentary understanding of genetics, they also learn that one of many forms of deafness can be inherited as an autosomal recessive trait. They plan to have children, and based on the above information, they are concerned that some or all of their children may be deaf. To their delight, their first child has normalhearing. The couple turns to you as a geneticist to help explain this situation.

Is it likely that these parents inherited their deafness as an autosomal recessive trait?

Expert Solution & Answer

Summary Introduction

To analyze:

The query of a deaf couple having a normal first child that whether the deafness in the couple is due to autosomal recessive inheritance.

Introduction:

In the given case, a deaf couple learn that they had relatives who were deaf. Despite the fact and expecting some of their children to be deaf, they bear a normal firstborn baby. Deafness, also known as hearing impairment, can be caused by genetic inheritance of trait from one generation to another. Inherited deafness is present in 50% (percent) of the deaf population.

Explanation of Solution

It can be inherited in the form of autosomal recessive trait or autosomal dominant trait. In autosomal recessive deafness, both the alleles for deafness must be present in order to cause deafness; whereas in autosomal dominant deafness, single allele is able to cause deafness in the offspring.

Parents do not have both the alleles for deafness, because the first child born is normal. In case, both had a pair of recessive allele for deafness, the first child would be deaf as well. Therefore, the deafness inherited in this case is not due to autosomal recessive inheritance.

If it was a case of recessive inheritance, then

DD X DD= DD; DD; DD; DD, all the children would be deaf. But, this is not true.

D: deaf, d: normal

Conclusion

Therefore, it can be concluded that this is not the case of autosomal recessive inheritance. Parents might have inherited deafness, but not through autosomal inheritance.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

A young lady requested pre-marital genetic counselling because her sister had died in infancy of gangliosidosis, an autosomal recessive disease. What is the risk that this young lady has similarly affected offspring? What advice should be given?

Genetic Inheritance Patterms Retinitis pigmnentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently the dominant forms are often less severe. Eric's form of RP is Usher's Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective gene from your Mom and one from your Dad). Autosomal means it is not carried on one of the chromosomes that determines sex. Usher's Type II is recessive, so for Eric this means that both his Mom and Dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. Question below - short answer approach Imagine you are a genetics counselor, and Dirk, Erik's brother, comes in to see you. Based on his parents, what are Dirk's possible genotypes for RP? What advice would you give Dirk about the chances of Dirk's children having retinitis pigmentosa if his wife is not a carrier? How would your advice change if his wife fully has the disease? Describe all the possibilities,…

Consider the following pedigree. 하 3 10 (5 3 2 (a) What pattern of transmission is most consistent with this pedigree? (1) autosomal recessive, (2) autosomal dominant, (3) X-linked recessive, (4) X-linked dominant. (b) If individual V-2 marries a normal individual, and if the condition has a pene-trance of 85 percent, what is the probability that their second child will express the trait? (c) On the third line, what does the diamond with a 10 in the middle mean?

Answer 2

Textbook Question

Chapter 4, Problem 1CS

CASE STUDY | But he isn't deaf

Researching their family histories, a deaf couple learns that each of them has relatives through several generations who are deaf. With a rudimentary understanding of genetics, they also learn that one of many forms of deafness can be inherited as an autosomal recessive trait. They plan to have children, and based on the above information, they are concerned that some or all of their children may be deaf. To their delight, their first child has normalhearing. The couple turns to you as a geneticist to help explain this situation.

Is it likely that these parents inherited their deafness as an autosomal recessive trait?

Expert Solution & Answer

Summary Introduction

To analyze:

The query of a deaf couple having a normal first child that whether the deafness in the couple is due to autosomal recessive inheritance.

Introduction:

In the given case, a deaf couple learn that they had relatives who were deaf. Despite the fact and expecting some of their children to be deaf, they bear a normal firstborn baby. Deafness, also known as hearing impairment, can be caused by genetic inheritance of trait from one generation to another. Inherited deafness is present in 50% (percent) of the deaf population.

Explanation of Solution

It can be inherited in the form of autosomal recessive trait or autosomal dominant trait. In autosomal recessive deafness, both the alleles for deafness must be present in order to cause deafness; whereas in autosomal dominant deafness, single allele is able to cause deafness in the offspring.

Parents do not have both the alleles for deafness, because the first child born is normal. In case, both had a pair of recessive allele for deafness, the first child would be deaf as well. Therefore, the deafness inherited in this case is not due to autosomal recessive inheritance.

If it was a case of recessive inheritance, then

DD X DD= DD; DD; DD; DD, all the children would be deaf. But, this is not true.

D: deaf, d: normal

Conclusion

Therefore, it can be concluded that this is not the case of autosomal recessive inheritance. Parents might have inherited deafness, but not through autosomal inheritance.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Textbook Question

Chapter 4, Problem 1CS

CASE STUDY | But he isn't deaf

Researching their family histories, a deaf couple learns that each of them has relatives through several generations who are deaf. With a rudimentary understanding of genetics, they also learn that one of many forms of deafness can be inherited as an autosomal recessive trait. They plan to have children, and based on the above information, they are concerned that some or all of their children may be deaf. To their delight, their first child has normalhearing. The couple turns to you as a geneticist to help explain this situation.

Is it likely that these parents inherited their deafness as an autosomal recessive trait?

Expert Solution & Answer

Summary Introduction

To analyze:

The query of a deaf couple having a normal first child that whether the deafness in the couple is due to autosomal recessive inheritance.

Introduction:

In the given case, a deaf couple learn that they had relatives who were deaf. Despite the fact and expecting some of their children to be deaf, they bear a normal firstborn baby. Deafness, also known as hearing impairment, can be caused by genetic inheritance of trait from one generation to another. Inherited deafness is present in 50% (percent) of the deaf population.

Explanation of Solution

It can be inherited in the form of autosomal recessive trait or autosomal dominant trait. In autosomal recessive deafness, both the alleles for deafness must be present in order to cause deafness; whereas in autosomal dominant deafness, single allele is able to cause deafness in the offspring.

Parents do not have both the alleles for deafness, because the first child born is normal. In case, both had a pair of recessive allele for deafness, the first child would be deaf as well. Therefore, the deafness inherited in this case is not due to autosomal recessive inheritance.

If it was a case of recessive inheritance, then

DD X DD= DD; DD; DD; DD, all the children would be deaf. But, this is not true.

D: deaf, d: normal

Conclusion

Therefore, it can be concluded that this is not the case of autosomal recessive inheritance. Parents might have inherited deafness, but not through autosomal inheritance.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Textbook Question

Chapter 4, Problem 1CS

CASE STUDY | But he isn't deaf

Researching their family histories, a deaf couple learns that each of them has relatives through several generations who are deaf. With a rudimentary understanding of genetics, they also learn that one of many forms of deafness can be inherited as an autosomal recessive trait. They plan to have children, and based on the above information, they are concerned that some or all of their children may be deaf. To their delight, their first child has normalhearing. The couple turns to you as a geneticist to help explain this situation.

Is it likely that these parents inherited their deafness as an autosomal recessive trait?

Expert Solution & Answer

Summary Introduction

To analyze:

The query of a deaf couple having a normal first child that whether the deafness in the couple is due to autosomal recessive inheritance.

Introduction:

In the given case, a deaf couple learn that they had relatives who were deaf. Despite the fact and expecting some of their children to be deaf, they bear a normal firstborn baby. Deafness, also known as hearing impairment, can be caused by genetic inheritance of trait from one generation to another. Inherited deafness is present in 50% (percent) of the deaf population.

Explanation of Solution

It can be inherited in the form of autosomal recessive trait or autosomal dominant trait. In autosomal recessive deafness, both the alleles for deafness must be present in order to cause deafness; whereas in autosomal dominant deafness, single allele is able to cause deafness in the offspring.

Parents do not have both the alleles for deafness, because the first child born is normal. In case, both had a pair of recessive allele for deafness, the first child would be deaf as well. Therefore, the deafness inherited in this case is not due to autosomal recessive inheritance.

If it was a case of recessive inheritance, then

DD X DD= DD; DD; DD; DD, all the children would be deaf. But, this is not true.

D: deaf, d: normal

Conclusion

Therefore, it can be concluded that this is not the case of autosomal recessive inheritance. Parents might have inherited deafness, but not through autosomal inheritance.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

To analyze:

The query of a deaf couple having a normal first child that whether the deafness in the couple is due to autosomal recessive inheritance.

Introduction:

In the given case, a deaf couple learn that they had relatives who were deaf. Despite the fact and expecting some of their children to be deaf, they bear a normal firstborn baby. Deafness, also known as hearing impairment, can be caused by genetic inheritance of trait from one generation to another. Inherited deafness is present in 50% (percent) of the deaf population.

Explanation of Solution

It can be inherited in the form of autosomal recessive trait or autosomal dominant trait. In autosomal recessive deafness, both the alleles for deafness must be present in order to cause deafness; whereas in autosomal dominant deafness, single allele is able to cause deafness in the offspring.

Parents do not have both the alleles for deafness, because the first child born is normal. In case, both had a pair of recessive allele for deafness, the first child would be deaf as well. Therefore, the deafness inherited in this case is not due to autosomal recessive inheritance.

If it was a case of recessive inheritance, then

DD X DD= DD; DD; DD; DD, all the children would be deaf. But, this is not true.

D: deaf, d: normal

Conclusion

Therefore, it can be concluded that this is not the case of autosomal recessive inheritance. Parents might have inherited deafness, but not through autosomal inheritance.

Answer 8

Expert Solution & Answer

Summary Introduction

To analyze:

The query of a deaf couple having a normal first child that whether the deafness in the couple is due to autosomal recessive inheritance.

Introduction:

In the given case, a deaf couple learn that they had relatives who were deaf. Despite the fact and expecting some of their children to be deaf, they bear a normal firstborn baby. Deafness, also known as hearing impairment, can be caused by genetic inheritance of trait from one generation to another. Inherited deafness is present in 50% (percent) of the deaf population.

Explanation of Solution

It can be inherited in the form of autosomal recessive trait or autosomal dominant trait. In autosomal recessive deafness, both the alleles for deafness must be present in order to cause deafness; whereas in autosomal dominant deafness, single allele is able to cause deafness in the offspring.

Parents do not have both the alleles for deafness, because the first child born is normal. In case, both had a pair of recessive allele for deafness, the first child would be deaf as well. Therefore, the deafness inherited in this case is not due to autosomal recessive inheritance.

If it was a case of recessive inheritance, then

DD X DD= DD; DD; DD; DD, all the children would be deaf. But, this is not true.

D: deaf, d: normal

Conclusion

Therefore, it can be concluded that this is not the case of autosomal recessive inheritance. Parents might have inherited deafness, but not through autosomal inheritance.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

To analyze:

The query of a deaf couple having a normal first child that whether the deafness in the couple is due to autosomal recessive inheritance.

Introduction:

In the given case, a deaf couple learn that they had relatives who were deaf. Despite the fact and expecting some of their children to be deaf, they bear a normal firstborn baby. Deafness, also known as hearing impairment, can be caused by genetic inheritance of trait from one generation to another. Inherited deafness is present in 50% (percent) of the deaf population.

Answer 12

Explanation of Solution

It can be inherited in the form of autosomal recessive trait or autosomal dominant trait. In autosomal recessive deafness, both the alleles for deafness must be present in order to cause deafness; whereas in autosomal dominant deafness, single allele is able to cause deafness in the offspring.

Parents do not have both the alleles for deafness, because the first child born is normal. In case, both had a pair of recessive allele for deafness, the first child would be deaf as well. Therefore, the deafness inherited in this case is not due to autosomal recessive inheritance.

If it was a case of recessive inheritance, then

DD X DD= DD; DD; DD; DD, all the children would be deaf. But, this is not true.

D: deaf, d: normal

Answer 13

Conclusion

Therefore, it can be concluded that this is not the case of autosomal recessive inheritance. Parents might have inherited deafness, but not through autosomal inheritance.

Answer 14

Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 - CASE STUDY | But he isn’t deaf Researching...Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - Review the Chapter Concepts list on page 53. These...Ch. 4 - In Shorthorn cattle, coat color may be red, white,...Ch. 4 - 4. With regard to the ABO blood types in humans,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in the plants of Problem 6, color may be red,...

Concept explainers

Videos

Explanation of Solution

Want to see more full solutions like this?

Chapter 4 Solutions