Essentials of Genetics
9th Edition
ISBN: 9781292108933
Author: KLUG
Publisher: PEARSON
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Chapter 4, Problem 27PDQ
Two mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia, a disease caused by an X-linked recessive allele. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?
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Two mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is afflicted with hemophilia, a disease caused by an X-linked recessive allele. Neither parent has the disease. Mother 2 has a normal son, despite the fact that the father has hemophilia. Several years later, couple 1 sues the hospital, claiming that these two newborns were swapped in the nursery following their birth. As a genetic counselor, you are called to testify. What information can you provide the jury concerning the allegation?
In humans, the genes for colorblindness and hemophilia are both located on the X chromosome with no corresponding gene in the Y. These are both recessive alleles.
If a man and a woman, both with normal vision, marry and have a colorblind son, draw the Punnet square that illustrates this.
If the man dies and the woman remarries a colorblind man, draw a Punnet Square showing the type of children that could be expected from the second marriage. How many/what percentages of each could be expected.
Red-green color blindness is inherited as an X-linked recessive (Xc). If a color-blind man marries a woman who is heterozygous for normal vision, what would be the expected phenotypes of their children with reference to this character? In your answer, specify in your phenotype descriptions the gender of the children. (For example, don’t just say 75% of the children would be colorblind – you would instead say 100 % of the daughters would be colorblind and 50% of the sons would be colorblind. Note that this is not a correct answer; it is just to give you an idea of how to explain the correct phenotypes of the cross.)___
Chapter 4 Solutions
Essentials of Genetics
Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 -
CASE STUDY | But he isn’t deaf
Researching...Ch. 4 - CASE STUDY | But he isn't deaf Researching their...Ch. 4 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 4 - Review the Chapter Concepts list on page 53. These...Ch. 4 - In Shorthorn cattle, coat color may be red, white,...Ch. 4 -
4. With regard to the ABO blood types in humans,...Ch. 4 - In foxes, two alleles of a single gene, P and p,...Ch. 4 - Three gene pairs located on separate autosomes...Ch. 4 - As in the plants of Problem 6, color may be red,...
Ch. 4 -
8. The following genotypes of two independently...Ch. 4 - Given the inheritance pattern of coat color in...Ch. 4 - A husband and wife have normal vision, although...Ch. 4 - In humans, the ABO blood type is under the control...Ch. 4 - In goals, development of the beard is due to a...Ch. 4 -
13. In cats, orange coal color is determined by...Ch. 4 - In Drosophila, an X-linked recessive mutation,...Ch. 4 - Another recessive mutation in Drosophila, ebony...Ch. 4 - While vermilion is X-linked in Drosophila and...Ch. 4 - In pigs, coat color may be sandy, red, or white. A...Ch. 4 - A geneticist from an alien planet that prohibits...Ch. 4 - In another cross, the frog geneticist from Problem...Ch. 4 - In cattle, coats may be solid white, solid black,...Ch. 4 - Consider the following three pedigrees, all...Ch. 4 - Labrador retrievers may be black, brown, or golden...Ch. 4 - Three autosomal recessive mutations in Drosophila,...Ch. 4 -
24. Horses can be cremello (a light cream...Ch. 4 - Pigment in the mouse is produced only when the C...Ch. 4 - Five human matings numbered 1–5 are shown in the...Ch. 4 - Two mothers give birth to sons at the same time at...Ch. 4 - In Dexter and Kerry cattle, animals may be polled...Ch. 4 - What genetic criteria distinguish a case of...Ch. 4 -
30. The specification of the anterior-posterior...Ch. 4 - The maternal-effect mutation bicoid(bcd)is...Ch. 4 -
32. Students taking a genetics exam were...Ch. 4 - In four o'clock plants, many flower colors are...Ch. 4 - Prob. 34PDQ
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Cystic fibrosis is an autosomal disease that mainly affects the white population, and 1 in 20 whites are heterozygotes. Genetic testing can diagnose heterozygotes. Should a genetic screening program for cystic fibrosis be instituted? Should the federal government fund it? Should the program be voluntary or mandatory, and why?arrow_forwardA proband female with an unidentified disease seeks the advice of a genetic counselor before starting a family. Based on the following data, the counselor constructs a pedigree encompassing three generations: (1) The maternal grandfather of the proband has the disease. (2) The mother of the proband is unaffected and is the youngest of five children, the three oldest being male. (3) The proband has an affected older sister, but the youngest siblings are unaffected twins (boy and girl). (4) All the individuals who have the disease have been revealed. Duplicate the counselors featarrow_forwardTwo mothers give birth to sons at the same time at a busy urbanhospital. The son of mother 1 has hemophilia, a disease causedby an X-linked recessive allele. Neither parent has the disease.Mother 2 has a son without hemophilia, despite the fact thatthe father has hemophilia. Several years later, couple 1 suesthe hospital, claiming that these two newborns were swappedin the nursery following their birth. As a genetic counselor, youare called to testify. What information can you provide the juryconcerning the allegation?arrow_forward
- A type of red-green colorblindness is inherited recessively on the X chromosome. A woman who is a carrier had children with a male that is not affected by the disease. Show your answers with the use of a Punnett square • What is the probability (% or likelihood) that a child is affected by the disease? • What is the probability (% or likelihood) that a son is a carrier? (Careful!) • Is there a chance that a girl of the couple is affected by the disease?arrow_forwardSuppose gene B is X-linked and is embryonically lethal when homozygous or hemizygous recessive. A man marries a woman who is heterozygous for this gene. They want to have three kids – one girl and two boys. Using a Punnett square, answer the following: What is the probability that they will have a son that dies before birth? _______________________ What is the probability that they will have a daughter who has the same genotype as her mother? _________________ One of their daughters eventually has a child with a man. One of their sons dies before birth. What was the genotype of this daughter? _______________________________ please show me how to get the answer and explain how you got and use a punnet squarearrow_forwardIn humans, blue eyes are inherited as a recessive autosomal trait and color blindness is an X-linked recessive trait. A woman with blue eyes and normal color vision (her father was colorblind) marries a man who has normal color vision. The man has brown eyes, but his mother had blue eyes. What is the probability that this couple will have a child with normal vision and blue eyes?arrow_forward
- In humans, blue eyes are inherited as a recessive autosomal trait and color blindness is an X-linked recessive trait. A woman with blue eyes and normal color vision (her father was colorblind) marries a man who has normal color vision. The man has brown eyes, but his mother had blue eyes. What is the probability that this couple will have a son with brown eyes? What is the probability that this couple will have a color blind son with blue eyes?arrow_forwardSkin color in humans is determined by polygenic inheritance, which means the more dominant alleles there are, the darker the skin color will be. A medium-toned skinned woman (AaBb) has a child with another medium-toned skinned man (AaBb). What is the probability of them having a very dark-toned skinned child? (Hint: the genotype is homozygous dominant)arrow_forwardA young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cysticfibrosis is a recessive disease, and neither member ofthe couple nor any of their four parents is affected.)a. What is the probability that the female of thiscouple is a carrier?b. What are the chances that their child will havecystic fibrosis?c. What is the probability that their child will be acarrier of the cystic fibrosis disease allele?arrow_forward
- Imagine that you are a genetic counselor, and a couple planning to start a family comes to you for information. Charles wasmarried once before, and he and his first wife had a child withcystic fibrosis. The brother of his current wife, Elaine, died ofcystic fibrosis. What is the probability that Charles and Elainewill have a baby with cystic fibrosis? (Neither Charles, Elaine,nor their parents have cystic fibrosis.)arrow_forwardIn human beings, the gene for red‑green colorblindness (r) is sex‑linked and recessive to its allele for normal vision (R), while the gene for freckles (F) is autosomal and dominant over its allele for nonfreckled (f). A nonfreckled, normal‑visioned woman whose father was freckled and colorblind, marries a freckled, colorblind man whose mother was nonfreckled. What is the genotype of the woman's father? What is the probability that the couple's first child will be a non-freckled, normal visioned girl? What is the probability that the first two children born to the couple will be freckled and colorblind girls?arrow_forwardIn the pedigree attached, the shaded symbols represent people affected with a neurological disorder caused by an X-linked recessive allele. The normal allele is D and the recessive allele is d. What are the genotypes of every person in this pedigree? Please explain in as much detail as possible.arrow_forward
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