ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260406092
Author: HARTWELL, Leland, HOOD, Leroy, Goldberg, Michael
Publisher: Mcgraw-hill Education/stony Brook University
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Chapter 4, Problem 32P
In a vial of Drosophila, a research student noticed several female flies (but no male flies) with bag wings each consisting of a large, liquid-filled blister instead of the usual smooth wing blade. When the bag-winged females were crossed with wild-type males, 1/3 of the progeny were bag-winged females, 1/3 were normal-winged females, and 1/3 were normal-winged males. Explain these results.
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In Drosophila, a cross was made between a yellow-bodied male with vestigial wings and a wild-type (WT) female(brown body and normal wings). The F1 generation consisted of WT males and WT females. The F1 males and females were crossed, and the F2 progeny consisted of 16 yellow males with vestigial wings, 48 yellow males with WT wings, 15 brown males with vestigial wings, 49 WT males, 31 brown females with vestigial wings, and 97 WT females. Based on these results, explain the inheritance of the two genes (i.e. autosomal or sex-linked, dominant or recessive).
In a cross between a white-eyed female (ww) and a red-eyed male (w+Y), nearly all the progeny were either red-eyed females (w+w) or white-eyed males (wY). However, about 1 in every 2000 F1 flies had an "exceptional phenotype" and was either a white-eyed female or red-eyed male. How did Bridges explain this unexpected result?
A) Crossing over
B) Incomplete cytokinesis
C) Incorrect synapsis
D) Nondisjunction
E) Pseudoautosomal region
In Drosophila,, the curled mutation (cu, chromosome 3, position 50.0) results in wings that curl up,
while ebony (e, chromosome 3, position 70.7) results in a dark body. True breeding, wild type females
are mated with true breeding males with curled wings and ebony bodies.
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Chapter 4 Solutions
ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
Ch. 4 - Choose the best matching phrase in the right...Ch. 4 - Humans have 46 chromosomes in each somatic cell....Ch. 4 - The figure that follows shows the metaphase...Ch. 4 - Human XX males who are sex-reversed because they...Ch. 4 - Researchers discovered recently that the sole...Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Indicate which of the cells numbered iv matches...Ch. 4 - a. What are the four major stages of the cell...Ch. 4 - Answer the questions that follow for each stage of...Ch. 4 - Can you think of anything that would prevent...
Ch. 4 - One oak tree cell with 14 chromosomes undergoes...Ch. 4 - Which types of cell division mitosis, meiosis I,...Ch. 4 - Complete the following statements using as many of...Ch. 4 - The five cells shown in figure a e are all from...Ch. 4 - One of the first microscopic observations of...Ch. 4 - A person is simultaneously heterozygous for two...Ch. 4 - Assuming i that the two chromosomes in every...Ch. 4 - In the moss Polytrichum commune, the haploid...Ch. 4 - Can you think of anything that would prevent...Ch. 4 - Sister chromatids are held together through...Ch. 4 - The pseudoautosomal regions PARs of the X and Y...Ch. 4 - Remarkably, the platypus has 10 sex chromosomes,...Ch. 4 - Somatic cells of chimpanzees contain 48...Ch. 4 - In humans: a. How many sperm develop from 100...Ch. 4 - Women sometimes develop benign tumors called...Ch. 4 - In a certain strain of turkeys, unfertilized eggs...Ch. 4 - Imagine you have two pure-breeding lines of...Ch. 4 - A system of sex determination known as...Ch. 4 - In Drosophila, the autosomal recessive brown eye...Ch. 4 - Barred feather pattern is a Z-linked dominant...Ch. 4 - When Calvin Bridges observed a large number of...Ch. 4 - In a vial of Drosophila, a research student...Ch. 4 - In 1919, Calvin Bridges began studying an X-linked...Ch. 4 - In Drosophila, a cross was made between a...Ch. 4 - As we learned in this chapter, the white mutation...Ch. 4 - The following is a pedigree of a family in which a...Ch. 4 - Each of the four pedigrees that follow represents...Ch. 4 - The pedigree that follows indicates the occurrence...Ch. 4 - Duchenne muscular dystrophy DMD is caused by a...Ch. 4 - The X-linked gene responsible for DMD encodes a...Ch. 4 - Males have hemophilia when they are hemizygous for...Ch. 4 - In the Fast Forward Box Visualizing X Chromosome...Ch. 4 - Consider the following pedigrees from human...Ch. 4 - Several different antigens can be detected in...Ch. 4 - The ancestry of a white female tiger bred in a...Ch. 4 - The pedigree that follows shows the inheritance of...Ch. 4 - In 1995, doctors reported a Chinese family in...Ch. 4 - In cats, the dominant O allele of the X-linked...Ch. 4 - In marsupials like the opposum or kangaroo, X...Ch. 4 - The pedigree diagram below shows a family in which...
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- In a vial of Drosophila, a research student noticedseveral female flies (but no male flies) with bag wingseach consisting of a large, liquid-filled blister insteadof the usual smooth wing blade. When bag-wingedfemales were crossed with wild-type males, 1/3 of theprogeny were bag-winged females, 1/3 were normalwinged females, and 1/3 were normal-winged males.Explain these results.arrow_forwardFemale flies with white eyes and miniature wings (both X-linkedrecessive traits) were crossed to male flies with red eyes and longwings. On rare occasions, female offspring were produced withwhite eyes. If we assume these females are due to errors in meiosis, what would be the most likely chromosomal composition ofsuch flies? What would be their wing length?arrow_forwardIn Drosophila, a cross was made between females—all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)—and wild-type males. In the F1, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F2 generation, and 1000 offspring were counted, with the results shown in the following table. Phenotype Offspring sc s v 314 + + + 280 + s v 150 sc + + 156 sc + v 46 + s + 30 sc s + 10 + + v 14 No determination of sex was made in the data. (a) Using proper nomenclature, determine the genotypes of the P1 and F1 parents. (b) Determine the sequence of the three genes and the map distances between them. (c) Are there more or fewer double crossovers than expected? (d) Calculate the coefficient of coincidence. Does it represent positive or negative interference?arrow_forward
- In Drosophila,, the curled mutation (cu, chromosome 3, position 50.0) results in wings that curl up, while ebony (e, chromosome 3, position 70.7) results in a dark body. True breeding, wild type females are mated with true breeding males with curled wings and ebony bodies. Considering Drosophila notation, which of the following correctly diagrams the F1 cross? X X 3+ cu e + X X e + + + + + cu e + O + ■ 3+ X X X X Y Y + + ■ cu cu cu ' + ■ cu ■ ' + e + e e e e e + cu +arrow_forwardA Drosophila strain with two mutated phenotypes was crossed with a wild-type Drosophila strain. The wild-type phenotypes were present in all of the F1 flies. The F1 flies were bred with one another. The F2 generation, on the other hand, did not have the predicted 9:3:3:1 phenotypic ratio. Explain why these outcomes occurred.arrow_forwardTwo Drosophila flies that had normal (transparent, long) wings were mated. In the progeny, two new phenotypes appeared, dusky wings (having a semi-opaque appearance) and clipped wings (with squared ends). The progeny were as follows: Females: 179 transparent, long 58 transparent, clipped Males: 92 transparent, long 89 dusky, long 28 transparent, clipped 31 dusky, clipped a) Provide a genetic explanation for these results, showing genotypes of parents and of all progeny classes under your model. b) Design a test for your model.arrow_forward
- In Drosophila, a cross was made between a yellowbodied male with vestigial (not fully developed)wings and a wild-type female (brown body). The F1generation consisted of wild-type males and wild-typefemales. F1 males and females were crossed, and theF2 progeny consisted of 16 yellow-bodied males withvestigial wings, 48 yellow-bodied males with normalwings, 15 males with brown bodies and vestigialwings, 49 wild-type males, 31 brown-bodied femaleswith vestigial wings, and 97 wild-type females.Explain the inheritance of the two genes in questionbased on these results.arrow_forwardFemales of wild-type Strain A and males of mutant Strain B, as well as females of mutant Strain B and males of wild-type Strain A, make reciprocal crosses. Explain why reciprocal crosses are needed in genetics experiments involving Drosophila fruit flies.arrow_forwardThe phenotype of crooked wings (cw) in Drosophila melanogaster is caused by a recessive mutant gene that independently assorts with a recessive mutant gene for hairy (h) body. Assume that a cross is made between a fly with normal wings and a hairy body and a fly with crooked wings and normal body hair. All F1 flies from this cross were wild-type, and these flies were crossed among each other to produce 288 F2 offspring. Which phenotypes would you expect among the offspring in the F2 generation, and how many of each phenotype would you expect?arrow_forward
- In Drosophila, males from a true-breeding stock with raspberry-colored eyes (instead of normal brownish-red eyes) were mated to females from a true-breeding stock with sable- colored bodies (instead of normal brown bodies). In the F, generation, all the females had wild-type eye and body color, while all the males had wild-type eye color but sable-colored bodies. When F, males and females were mated, the F generation was composed of: 216 females with wild-type eyes and bodies 223 females with wild-type eyes and sable bodies 191 males with wild-type eyes and sable bodies 188 males with raspberry eyes and wild-type bodies 23 males with wild-type eyes and bodies 27 males with raspberry eyes and sable bodies. Explain these results by diagramming the crosses and calculating any relevant map distances.arrow_forwardAnother cross in Drosophila involved the recessive, X-linked genes yellow (y), white (w), and cut (ct). A yellow-bodied, white-eyed female with normal wings was crossed to a male whose eyes and body were normal but whose wings were cut. The F1 females were wild type for all three traits, while the F1 males expressed the yellow-body and white-eye traits. The cross was carried to an F2 progeny, and only male offspring were tallied. On the basis of the data shown here, a genetic map was constructed. Phenotype Male Offspring y + ct 9 + w + 6 y w ct 90 + + + 95 + + ct 424 y w + 376 y + + 0 + w ct 0 (a) Diagram the genotypes of the F1 parents. (b) Construct a map, assuming that white is at locus 1.5 on the X chromosome. (c) Were any double-crossover offspring expected? (d) Could the F2 female offspring be used to construct the map? Why or why not?arrow_forwardAnother cross in Drosophila involved the recessive, X-linked genes yellow (y), white (w) and cut (ct). A yellow-bodied, white-eyed female with normal wings was crossed to a male whose eyes and body were normal but whose wings were cut. The F1 females were wild type for all three traits, while the F1 males expressed the yellow-body and white eyes traits. The cross was carried to an F2 progeny and only male offspring were tallied. Based on the data shown here, a genetic map was constructed. a) Diagram the genotypes of the F1 parents. b) Construct a map, assuming the white is at locus 1.5 on the X-chromosome. Phenotype Male offspring y + ct 9 + w + 6 y w ct 90 + + + 95 + + ct 424 y w + 376 y + + 0 + w ct 0arrow_forward
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