CAMPBELL BIOLOGY RUTGERS 115 >C<
CAMPBELL BIOLOGY RUTGERS 115 >C<
F13 Edition
ISBN: 9781269566056
Author: Reece
Publisher: Pearson Custom Publishing
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Chapter 43.1, Problem 2CC

MAKE CONNECTIONS Ø How do the molecules that activate the vertebrate TLR signal transduction pathway differ from the ligands in most other signaling pathways (see Concept 11.2)?

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DRAW IT Draw the following apoptotic pathway, whichoperates in human immune cells. A death signal isreceived when a molecule called Fas binds its cell-surfacereceptor. The binding of many Fas molecules to receptorscauses receptor clustering. The intracellular regions of thereceptors, when together, bind proteins called adaptorproteins. These in turn bind to inactive molecules ofcaspase-8, which become activated and then activatecaspase-3. Once activated, caspase-3 initiates apoptosis.
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