Campbell Biology, Books a la Carte Edition (11th Edition)
Campbell Biology, Books a la Carte Edition (11th Edition)
11th Edition
ISBN: 9780134154121
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 43.2, Problem 1CC
Summary Introduction

To draw: The structure of B-cell antigen and features located relative to V and C regions

Concept introduction:

The structure of a B cell resembles the “Y” shape. It consists of four polypeptide chains that include two identical heavy chains and, two identical light chains.

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Sketch a B cell antigen receptor. Label the V and C regions of the light and heavy chains. Label the antigenbinding sites, disulfide bridges, and transmembrane region. Where are these features located relative to the V and C regions?
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What physiological effect would you predict from a mutation that replacedwith serine the cysteine in the constant part of the immunoglobulin lightchain that is involved in disulfide-bond formation with the heavy chain?(as shown)
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