Concept explainers
To discuss:
Why some individuals may not exhibit the
Introduction:
DNA is a genetic material consisting of a long stretch of
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A&P UNITY AND FUNCTION ACCESS
- True or false? Gene expression patterns can be inherited.arrow_forwardFill in the Blanks When two alleles are equally expressed, this is called (blank) .arrow_forwardSuppose a maternal effect gene exists as a functional dominantallele and a nonfunctional recessive allele. A mother who is phenotypically abnormal produces all normal offspring. Explain thegenotype of the motherarrow_forward
- Mendelian Genetics and Non-Mendelian Genetics: Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jillian is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Jacobwhose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. 1. Give the genotypes of Jillian and Jacob. Assuming that they will have 4 children, what is the probability that: 2. all their children will be normal? 3. they will have a son with Huntington’s disease? 4. they will have a daughter inflicted with both conditionsarrow_forwardWhen both the alleles of a gene express themselves in heterozygous condition, the phenomenon is called---------arrow_forwardGenes on one gene that affect the expression of genes at different locations are said to be alleles epistatic continuous linkedarrow_forward
- Neo-Mendelian Genetics: Complete dominance and overdominance Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Mary is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibits sickle cell anemia. What are the genotypes of Mary and Paul? If they plan to have four children, what is the probability that: all their children will be normal? ____________ they will have a son with Huntington’s disease? ___________ they will have a daughter inflicted with both conditions?____________arrow_forwardStudy of how the inheritance of traits encoded by genes on sex chromosomes (sex-linked traits) differs from the inheritance of traits encoded by genes on nonsex chromosomes (autosomal traits) , indicate whether it focuses on transmission genetics, molecular genetics, or population geneticsarrow_forwardWhy some people resort to phenocopy? Numerically list down two pros and cons of phenocopying Comment in not more than 30 words these lines. “ No two people are exactly alike. Even monozygotic twins differ from each other”.arrow_forward
- Suppose a man and a woman are each heterozygous carriers of a mutation causing a fatal hereditary disease not on the RUSP list. Prenatal genetic testing can identify the genotype of a fetus with regard to this disease and can identify fetuses with the disease. What do you think are the three or four most important factors this couple should consider in their decision making about having children?arrow_forwardA woman diagnosed with early-onset Alzheimer's due to a mutation of the APP genehas children with a man that has no family history of familial Alzheimer's. Give the probability of each possible genotype with corresponding phenotype. (The woman has two possible allele combinations. You must show both possibilities)arrow_forwardA modification of a gene or chromosome that occurs during gamete formation or early development that permanently alters the expression of that gene for the lifetime of the individual is called O extranuclear inheritance. epistasis. O maternal effect. O epigenetic inheritance.arrow_forward
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