Concept explainers
To discuss:
Dominant and recessive alleles; the difference between the homozygous and heterozygous individuals; why some alleles are homozygous; and others are heterozygous in a person.
Introduction:
DNA is a genetic material consisting of a long stretch of
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- Mendelian Genetics and Non-Mendelian Genetics: Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jillian is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Jacobwhose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. 1. Give the genotypes of Jillian and Jacob. Assuming that they will have 4 children, what is the probability that: 2. all their children will be normal? 3. they will have a son with Huntington’s disease? 4. they will have a daughter inflicted with both conditionsarrow_forwardan example of a condition which is inherited via homozygous genes and one which is heterozygous. Do not use things like hair color or the color of Mendel’s pea plants here- discuss genetic disordersarrow_forwardWhy most loss-of-function mutant alleles are recessive to wild-type allelesarrow_forward
- Difference between allelic variation and chromosomal abbreviationsarrow_forwardThe differences between the genotype,genome, and gene pool; why a genotype cannever be composed of more than two allelesof the same gene, but the gene pool cancontain three or more alleles of one genearrow_forwardhow An inversion can affect phenotypearrow_forward
- Mendel crossed purebred purple-flowered plants with purebred white-flowered plants, and all of the resulting offspring produced purple flowers. The offspring are all and the allele for purple flowers is O homozygotes; recessive O heterozygotes; recessive O heterozygotes; dominant homozygotes; dominantarrow_forwardMultiple correct answersarrow_forwardNeo-Mendelian Genetics: Complete dominance and overdominance Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Mary is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married Paul whose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibits sickle cell anemia. What are the genotypes of Mary and Paul? If they plan to have four children, what is the probability that: all their children will be normal? ____________ they will have a son with Huntington’s disease? ___________ they will have a daughter inflicted with both conditions?____________arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning