ANATOMY+PHYS VOL 1(CHP 1-17) >CUSTOM<
9th Edition
ISBN: 9781307677706
Author: SALADIN
Publisher: MCG/CREATE
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Chapter 4.4, Problem 9AYLO
Summary Introduction
To discuss:
What polygenic inheritance and pleiotropy suggest about the relationship between a certain
Introduction:
DNA is a genetic material consisting of a long stretch of
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Suppose a maternal effect gene exists as a functional dominantallele and a nonfunctional recessive allele. A mother who is phenotypically abnormal produces all normal offspring. Explain thegenotype of the mother
F1 and F2 offspring with given genders and disease phenotypes.
The data are generated from an initial parental cross.
One parent displays the disease phenotype and one displays the wild-type (WT) phenotype.
The WT parent always has a homozygous genotype.
There are three possible modes of inheritance that underlie
the generation of the data. All are monogenic. They are:
(i) Autosomal Recessive.
(ii) Homozygous Lethal Dominant.
(iii) Autosomal Dominant.
One's phenotype is determined by their genotype at the disease locus
and the mode of inheritance, as we have seen with Punnett Square.
on the F2 data and make a decision, based on your statistical analysis, as to whether
you reject or do not reject the computer-generated model of inheritance as being consistent
with the observed data.
The mode of inheritance you are to test on the observed data is autosomal recessive.
PARENTAL CROSS
Parental cross: Father with disease phenotype, Mother with wild-type phenotype.
F1 DATA
Phenotype…
Suppose a maternal effect gene exists as a functional dominantallele and a nonfunctional recessive allele that causes a disorder.A mother with the disorder produces offspring that are all withoutthe disorder. Explain the genotype of the mother.
Chapter 4 Solutions
ANATOMY+PHYS VOL 1(CHP 1-17) >CUSTOM<
Ch. 4.1 - What are the three components of a nucleotide?...Ch. 4.1 - What governs the pattern of base paring in DNA?Ch. 4.1 - what is the difference between DNA and chromatin?Ch. 4.1 - Summarize the structural and functional...Ch. 4.1 - The general name of the monomers that compose DNA...Ch. 4.1 - Prob. 2AYLOCh. 4.1 - Prob. 3AYLOCh. 4.1 - How DNA and protein are combined to form...Ch. 4.1 - Prob. 5AYLOCh. 4.1 - HOW RNA differs from DNA in structure and...
Ch. 4.2 - Prob. 5BYGOCh. 4.2 - Describe the roles of RNA polymerase ribosomes,...Ch. 4.2 - What is the difference between genetic...Ch. 4.2 - Summarize the processing of a protein from the...Ch. 4.2 - Prob. 9BYGOCh. 4.2 - Prob. 10BYGOCh. 4.2 - Prob. 1AYLOCh. 4.2 - Prob. 2AYLOCh. 4.2 - The organization of nucleotides into DNA triplets;...Ch. 4.2 - How the genetic code relates mRNA codons to...Ch. 4.2 - The process and outcome of genetic transcription,...Ch. 4.2 - Prob. 6AYLOCh. 4.2 - Prob. 7AYLOCh. 4.2 - Prob. 8AYLOCh. 4.2 - Prob. 9AYLOCh. 4.2 - Prob. 10AYLOCh. 4.3 - Describe the genetic roles of DNA helicase and DNA...Ch. 4.3 - Explain why DNA replication is called...Ch. 4.3 - Define mutation. Explain why some mutations are...Ch. 4.3 - Prob. 14BYGOCh. 4.3 - Prob. 15BYGOCh. 4.3 - Prob. 16BYGOCh. 4.3 - Prob. 1AYLOCh. 4.3 - Semiconservative replication, the enzymes that...Ch. 4.3 - What a mutation is and how a cell detects and...Ch. 4.3 - The four stages of the cell cycle, what occurs in...Ch. 4.3 - Prob. 5AYLOCh. 4.3 - Cytokinesis and how it overlaps but differs from...Ch. 4.3 - Prob. 7AYLOCh. 4.3 - Prob. 8AYLOCh. 4.4 - Why must the carrier of a genetic disease be...Ch. 4.4 - Prob. 18BYGOCh. 4.4 - Prob. 19BYGOCh. 4.4 - Prob. 1AYLOCh. 4.4 - Organization of the karyotype; the number of...Ch. 4.4 - Prob. 3AYLOCh. 4.4 - Prob. 4AYLOCh. 4.4 - Prob. 5AYLOCh. 4.4 - Why a recessive trait can skip a generation, with...Ch. 4.4 - The differences between the genotype, genome, and...Ch. 4.4 - Prob. 8AYLOCh. 4.4 - Prob. 9AYLOCh. 4.4 - Prob. 10AYLOCh. 4.4 - Prob. 11AYLOCh. 4.4 - Prob. 12AYLOCh. 4.4 - Why it cannot be said that dominant alleles are...Ch. 4.4 - Prob. 14AYLOCh. 4.4 - Prob. 15AYLOCh. 4 - Production of more than one phenotypic trait by a...Ch. 4 - When a ribosome reads a codon on mRNA, it must...Ch. 4 - Prob. 3TYRCh. 4 - Two genetically identical strands of a metaphase...Ch. 4 - Prob. 5TYRCh. 4 - Genetic transcription is performed by a....Ch. 4 - Prob. 7TYRCh. 4 - Prob. 8TYRCh. 4 - Semiconservative replication occurs during a....Ch. 4 - Mutagens sometimes cause no harm to cells for all...Ch. 4 - The cytoplasmic division at the end of mitosis is...Ch. 4 - Prob. 12TYRCh. 4 - Prob. 13TYRCh. 4 - Prob. 14TYRCh. 4 - Prob. 15TYRCh. 4 - Prob. 16TYRCh. 4 - Prob. 17TYRCh. 4 - The cytoplasmic granule of RNA and protein that...Ch. 4 - Prob. 19TYRCh. 4 - Prob. 20TYRCh. 4 - Prob. 1BYMVCh. 4 - Prob. 2BYMVCh. 4 - Prob. 3BYMVCh. 4 - Prob. 4BYMVCh. 4 - Prob. 5BYMVCh. 4 - Prob. 6BYMVCh. 4 - Prob. 7BYMVCh. 4 - Prob. 8BYMVCh. 4 - Prob. 9BYMVCh. 4 - Prob. 10BYMVCh. 4 - Prob. 1WWTSCh. 4 - Steroids, carbohydrates, and phospholipids are...Ch. 4 - Prob. 3WWTSCh. 4 - Prob. 4WWTSCh. 4 - Prob. 5WWTSCh. 4 - The law of complementary base pairing describes...Ch. 4 - Prob. 7WWTSCh. 4 - All mutations result m the production of defective...Ch. 4 - Prob. 9WWTSCh. 4 - Prob. 10WWTSCh. 4 - Why world the supercoiled, condensed form of...Ch. 4 - Prob. 2TYCCh. 4 - Given the information in this chapter, present an...Ch. 4 - Prob. 4TYCCh. 4 - Prob. 5TYC
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- This is caused by the presence of certain cytoplasmic determinants from the expression of nuclear genes in the egg cell prior to fertilization. Delayed chromosomal inheritance Extrachromosomal Inheritance Codominance Inheritance Complete dominancearrow_forwardWhich of the following defines polygenic inheritance? An inheritance pattern in which one allele is not fully dominant over another, so the heterozygous phenotype is an intermediate blend of the two homozygous phenotypes An inheritance pattern in which the full and separate phenotypic effects of two alleles are apparent in heterozygous individuals An inheritance pattern in which a single gene affects multiple traits A pattern of inheritance in which multiple genes affect one traitarrow_forwardWhich genotype is indicative of the carriers of a trait associated with an autosomal recessive inheritance pattern? Tt TT tt All of thesearrow_forward
- Suppose a maternal effect gene exists as a functional dominant allele and a nonfunctional recessive allele. A mother with the disorder produces all offspring without the disorder. Explain the genotype of the mother.arrow_forwardWhy do human sex-linked recessive traits typically show up in sons more than daughters? Hint: consider the probabilities involved in the inheritance of such traits.arrow_forwardA morphological trait is the physical association between two genes because they are on the same chromosome, also the inheritance patterns showing dependant assortment of alleles that result from this association true or false?arrow_forward
- The mode of inheritance of the auricular hypertrichous trait in the Brown family is clearly an instance of: Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. b d recessive inheritance with the females being carriers. dominant inheritance with the males being carriers. X-linked inheritance, which is being expressed in the males since they only have one X chromosome. Y-linked inheritance, which can never be passed on to females.arrow_forwardconsidered the theory of the inheritance of acquired characteristics and noted that this theory is no longer accepted. Is the central dogma consistent with the theory of the inheritance of acquired characteristics? Why or why not?arrow_forwardDefine polygenic inheritance. List two human straits that follow this pattern of inheritance.arrow_forward
- A 31 year old woman consults her physicain because she is concerned about developing breast cancer. She is currently in good health and she has never had any breast disease. Her concem arises bacause her sister has just been diagnosed as having breast cancer and her mother died of breast cancer. How can one determine if the cancer in this family is likely to be a dominantly inherited predisposition? b. What is the woman's cahnce of developing breast cancer? а.arrow_forwardGeneral properties of Sex-linked Inheritance, traits is always passed from the father to son and only males are affected. *arrow_forwardExplain in your own words why the terms "dominant" and "recessive" in terms of genetic inheritance are context dependant. Typically, the terms dominant and recessive refer to the phenotype and not to alleles. In your answer, also explain why this is the case. If all cells carry the same DNA information, how is it that different cells may carry out different functions or that particular traits be expressed at different times of an organism's lifetime?arrow_forward
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