BIOLOGY (LL)
5th Edition
ISBN: 9781264115495
Author: BROOKER
Publisher: MCG
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Chapter 4.7, Problem 1CC
Summary Introduction
To determine: The reason behind incomplete synthesis of a protein in cytosol which is destined for ER.
Introduction: Every organelle present in a cell performs a specific function. Short amino acid sequences responsible for directing proteins to their location are known as sorting signals. A specific cellular component recognizes its corresponding sorting signal and the protein carrying that signal is redirected to its correct location.
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Is the whole protein (destined for the ER) synthesized and then moved to the ER or is it synthesized partially and then completed at the ER? Please explain.
What is the relationship between the Golgi apparatus and the ER in a protein-secreting cell?
"There is one strict requirement for the exit of a protein from the ER: it must be correctly folded" is true or false.
Chapter 4 Solutions
BIOLOGY (LL)
Ch. 4.1 - What properties of deep-sea vents made them...Ch. 4.1 - Which protobiont seems most similar to todays...Ch. 4.1 - Core Skill: Connections Look back at Figure 3.11....Ch. 4.1 - Prob. 3CCCh. 4.2 - Prob. 1CCCh. 4.2 - Prob. 2CCCh. 4.3 - Prob. 1CSCh. 4.3 - Prob. 1CCCh. 4.3 - Prob. 2CSCh. 4.4 - Prob. 1CS
Ch. 4.4 - Describe the type of movements that occur between...Ch. 4.4 - Prob. 2CSCh. 4.5 - Prob. 1CCCh. 4.5 - Prob. 1CSCh. 4.5 - If we consider the Golgi apparatus as three...Ch. 4.5 - The Nucleus and Endomembrane System Experimental...Ch. 4.5 - Prob. 2EQCh. 4.5 - Prob. 3EQCh. 4.5 - Prob. 3CCCh. 4.6 - Prob. 1CCCh. 4.6 - Core Skill: Connections Look ahead to Figure...Ch. 4.7 - Prob. 1CCCh. 4.7 - Prob. 2CCCh. 4 - The cell theory states that a. all living things...Ch. 4 - Prob. 2TYCh. 4 - Prob. 3TYCh. 4 - Prob. 4TYCh. 4 - Each of the following is part of the endomembrane...Ch. 4 - Prob. 6TYCh. 4 - Functions of the smooth endoplasmic reticulum...Ch. 4 - Prob. 8TYCh. 4 - Prob. 9TYCh. 4 - Which of the following observations would not be...Ch. 4 - What are the four stages that led to the origin of...Ch. 4 - Explain how motor proteins and cytoskeletal...Ch. 4 - Prob. 3CQCh. 4 - Discuss the roles of the genome and proteome in...Ch. 4 - Prob. 2COQ
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- Why is an ER signal sequence from a plasma membrane protein not sufficient to send a cytosolic protein to the plasma membrane?arrow_forwardHow do RER and SER differ from one another in terms of structure and function? List the processes in which the ER is involved.arrow_forwardIs fadh2 an enzyme?arrow_forward
- Is invertase intracellular or extracellular? Or both?arrow_forwardWhat is the energy source that powers the cotranslational movement of proteins across the endoplasmic reticulum?arrow_forwardAutophagy is an évolutionary conserved catabolic process devoted to the degradation of intracellular components. Which of the following would you observe during autophagy? Select all that apply MTOR inhibition through phosphorylation and activation of TSC proteins MTOR activation and phosphorylation of downstream target proteins Increased expression of Rab7 which mediates lysosomal fusion Acute inflammatory responsearrow_forward
- Explain the steps associated with translocation of ER proteins across the ER membrane.arrow_forwardMutations in the ribosomal protein gene RPS19 have been found to be associated with Diamond-Blackfan anemia (DBA), a rare syndrome that disrupts erythropoiesis, the process by which new red blood cells are produced. Which of the following provides the most likely explanation for the connection between a mutation in RPS19 and a disruption in erythropoiesis? A B с D The ribosomes in the cell are unable to package and transfer the components that are required for erythropoiesis. The ribosomes in the cell are unable to facilitate the movement of nutrients that are re- quired for erythropoiesis across the cell membrane. The ribosomes in the cell are unable to correctly synthesize the proteins that are re- sponsible for erythropoiesis. The ribosomes in the cell are unable to effectively produce the ATP that is required for erythropoiesis.arrow_forwardWhat would happen if an ER signal sequence was attached to a cytosolic protein?arrow_forward
- Which levels of regulation are utilized by both prokaryotic and eukaryotic cells/organisms? Which levels of regulation are unique to eukaryotic cells and why?arrow_forwardWhat would be the expected effect of attaching an ER signal sequence to a cytosolic protein?arrow_forwardWhat is the molecular mechanism that retains SCAP–SREBP in the ER when cholesterol is present but allows movement to the Golgi complex when cholesterol concentration is low?arrow_forward
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