GENETIC ANALYSIS: INTEGRATED - ACCESS
3rd Edition
ISBN: 9780135349298
Author: Sanders
Publisher: PEARSON
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Chapter 5, Problem 37P
For six genes known to be linked on chromosme
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Consider a maize plant: Genotype C/cm ; Ac/Ac+ where cm is an unstable colorless allele caused by Ds insertion. What phenotypic ratios would be produced and in what proportions when this plant is crossed with a mutant c/c Ac+/Ac+? Assume that the Ac and c loci are unlinked, that the chromosome-breakage frequency is negligible, and the C allele encodes pigment production.
In a series of mapping experiments, the recombination frequencies for four different linked genes of the Drosophila fly were determined, as shown in the figure. Based on this information, what is the most probable
order of these genes on the chromosome?
b 0
cn
90
rb
3.5 6.5 0
vg 19 9.0 16 0
b
cn rb vg
The numbers in the boxes are the
recombination frequencies in between the
genes (in percent).
O b-rb-cn-vg
O vg-cn-b-rb
Orb-cn-vg-b
b = black body
cn = cinnabar eyes
rb = reduced bristles
vg = vestigial wings
O vg-b-rb-cn
Recombination frequencies between four genetically-linked loci in corn are shown in the following table:
Loci Recombination Frequency (%)
L and Q 20
Q and R 50
R and L 30
Q and W 13
L and W 7
What is the order of the genes on the chromosome?
(note: The same answer can be represented forward or backwards. e.g. A B C D = D C B A)
LQWR
RQWL
LRQW
QRLW
RLWQ
Chapter 5 Solutions
GENETIC ANALYSIS: INTEGRATED - ACCESS
Ch. 5 - For parts a, b, and c, draw a diagram illustrating...Ch. 5 - 5.2 In a diploid species of plant, the genes for...Ch. 5 - A pure-breeding tall plant producing oval fruit as...Ch. 5 - 5.4 Genes E and H are syntenic in an experimental...Ch. 5 - In tomato plants, purple leaf color is controlled...Ch. 5 - 5.6 In Drosophila, the map positions of genes are...Ch. 5 - 5.7 Genes A, B, and C are linked on a chromosome...Ch. 5 - Gene G recombines with gene T at a frequency of...Ch. 5 - Genes A, B, C, D, and E are linked on a...Ch. 5 - Syntenic genes can assort independently. Explain...
Ch. 5 - 5.11 The recombination frequency between linked...Ch. 5 - On the DrosophilaX chromosome, the dominant allele...Ch. 5 - Researchers cross a corn plant that is pure -...Ch. 5 - 5.14 syndrome is an autosomal disorder affecting...Ch. 5 - 5.15 Three dominant traits of corn seedlings,...Ch. 5 - 5.16 In a diploid plant species, an with the...Ch. 5 - Prob. 17PCh. 5 - The Rh blood group in humans is determined by a...Ch. 5 - 5.19 Genetic linkage mapping for a large number of...Ch. 5 - 5.20 with the genotype form tetrads in the...Ch. 5 -
Gene and gene are genetically linked. Answer...Ch. 5 -
T. H. Morgan’s data on eye color and wing form,...Ch. 5 - Prob. 23PCh. 5 -
The boss in your laboratory has just heard of a...Ch. 5 - In rabbits, chocolate-colored fur (w+) is dominant...Ch. 5 - Prob. 26PCh. 5 - 5.27 In tomatoes, the allele for tall plant height...Ch. 5 - 5.28 Neurofibromatosis is an autosomal dominant...Ch. 5 - A 2006 genetic study of a large American family...Ch. 5 - 5.30 A experiment examining potential genetic...Ch. 5 - A genetic study of an early onset form of heart...Ch. 5 - In experiments published in 1918 that sought to...Ch. 5 - DNA sequence for 10 individuals are Identify the...Ch. 5 - 5.34 The accompanying pedigree below shows a...Ch. 5 - 5.35 Based on previous family studies, an...Ch. 5 - Divide a clean sheet of paper into four quadrant...Ch. 5 - 5.37 For six genes known to be linked on chromosme...
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- If 2 genes on the same chromosome have a recombination frequency of .01, what is the genetic distance from each other in map units?arrow_forwardRecombination frequencies between four genetically-linked loci in corn are shown in the following table: Loci Recombination Frequency (%) R and Q 45 W and Q 60 R and W 15 Q and L 10 L and R 35 What is the order of the genes on the chromosome? (note: The same answer can be represented forward or backwards. e.g. A B C D = D C B A) RQWL LQWR QWLR QRLW WRLQarrow_forwardYou are studying four linked genes located on chromosome 2 in the fruit fly Drosophila melanogaster: adp (which contributes to obesity), b (which contributes to body color), pr (which contributes to metabolism), and vg (which contributes to wing formation). A series of crosses between pair-wise combinations of these mutations yielded the following recombination frequencies between the indicated loci: pr and adp 9% adp and b 6% pr and b 3% vg and b 10% vg and pr 7% What is the genetic distance in map units (cM) between the adp and vg loci? 16 9 6 4arrow_forward
- For this particular family, what is the recombination rate between the D17S74 marker and the breast cancer gene? Lets say that at age 45 the third granddaughter III-3, is diagnosed with breast cancer. Now recalculate the recombination rate between the marker locus D17S74 and the breast cancer gene? Use only the 5 women in your analysis:the two daugthers in generation II and the three granddaughters in generation IIarrow_forwardTo determine the recombination frequency between body color and wing genes in flies, you perform several crosses where you cross an F1 having red body and smooth wings with a yellow-bodied, crinkle-winged fly. You get the following results. What is the distance between the genes for body color and wing surface in map units?arrow_forwardIn an electrophoretic gel across which is applied a powerful electrical alternating pulsed field, the DNA of the haploid fungus Neurospora crassa (n = 7) moves slowly but eventually forms seven bands, which represent DNA fractions that are of different sizes and hence have moved at different speeds. These bands are presumed to be the seven chromosomes. How would you show which band corresponds to which chromosome?arrow_forward
- In autotetraploid Chinese primrose (Primula sinensis L.), the gene controlling stigma color is very near the centromere of the chromosome carrying it. The allele G for green stigma is dominant to g for red stigmas. A homozygous green autotetraploid strain is crossed with a homozygous red autotetraploid strain. If the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the Fl be expected to produce? Derive the expected F2 phenotypic ratio.arrow_forwardConsider two loci A and B that are 30 cM apart on chromosome 1 in the fruit fly. A paracentric inversion is found to span about half of the distance between these loci, but not include either A or B. What is the approximate recombination frequency expected for these loci in … flies that are heterozygous for this inversion? RF(A-B) for heterozygous flies is … flies that are homozygous for this inversion? RF(A-B) for homozygous flies is …arrow_forwardIn a series of mapping experiments, the recombination frequencies for four different linked genes were determined as follows: vg= vestigial wings vg-b = 19 cn= cinnabar eyes vg-cn = 9 rb= reduced bristles vg-rb = 16 b= black body rb-b = 3.5 rb-cn = 6.5 cn-b = 9 Please map the genes in order on a chromosome. Which two genes are the closest together? What is your evidence?arrow_forward
- A yeast geneticist irradiates haploid cells of a strain that is an adenine-requiring auxotrophic mutant, caused by mutation of the gene ade1. Millions of the irradiated cells are plated on minimal medium, and a small number of cells divide and produce prototrophic colonies. These colonies are crossed individually with a wildtype strain. Two types of results are obtained:(1) prototroph × wild type : progeny all prototrophic(2) prototroph × wild type : progeny 75% prototrophic, 25% adenine-requiring auxotrophsa. Explain the difference between these two types of results.b. Write the genotypes of the prototrophs in each case.c. What progeny phenotypes and ratios do you predict from crossing a prototroph of type 2 by the original ade1auxotroph?arrow_forwardRecombination frequencies between three loci in corn are shown in the following table: Loci Recombination frequency (%) R and W2 17 R and L2 35 W2 and L2 18 What is the order of the genes on the chromosome?arrow_forwardIn D. melanogaster, reduced bristles (rd), cinnabar eyes (cn), and vestigial wings (vg) are recessive traits located on chromosome II in that order. The distance between rd and cn is 7 cM and the distance between cn and vg is 9 cM. The CoC for this chromosome is 0.9. A true-breeding female expressing cinnabar eyes and vestigial wings is crossed to a true-breeding male expressing reduced bristles. The F1 are wild type. An F1 female is then test crossed to a male expressing all three traits. Among the F2 progeny, how often would you expect to observe flies expressing only cinnabar eyes? Using the same information from above, among the F2 progeny, how often would you expect to observe completely wild-type flies?arrow_forward
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