GENETIC ANALYSIS: INTEGRATED - ACCESS
3rd Edition
ISBN: 9780135349298
Author: Sanders
Publisher: PEARSON
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Chapter 5, Problem 4P
Genes E and H are syntenic in an experimental organismwith the genotype
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In Neurospora, his2 mutants require the amino acidhistidine for growth, and lys4 mutants require theamino acid lysine. The two genes are on the samearm of the same chromosome, in the ordercentromere - his2 - lys4.A his2 mutant is mated with a lys4 mutant. Draw all ofthe possible ordered asci that could result from meioses in which the following events occurred, accountingfor the nutritional requirements for each ascospore.Ascospores without any copy of a chromosome willabort and die, turning white in the process.a. A single crossover between the centromere and his2b. A single crossover between his2 and lys4c. Nondisjunction during the first meiotic divisiond. Nondisjunction during the second meiotic divisione. A single crossover between the centromere andhis2, followed by nondisjunction during the firstmeiotic divisionf. A single crossover between his2 and lys4,followed by nondisjunction during the firstmeiotic division
Female flies with white eyes and miniature wings (both X-linkedrecessive traits) were crossed to male flies with red eyes and longwings. On rare occasions, female offspring were produced withwhite eyes. If we assume these females are due to errors in meiosis, what would be the most likely chromosomal composition ofsuch flies? What would be their wing length?
For each of the following types of chromosomalaberrations, tell: (i) whether the chromosomes of anorganism heterozygous for the aberration will formany type of loop during prophase I of meiosis;(ii) whether a chromosomal bridge can be formedduring anaphase I in a heterozygote, and if so, underwhat conditions; (iii) whether an acentric fragmentcan be formed during anaphase I in a heterozygote,and if so, under what conditions; (iv) whether theaberration can suppress meiotic recombination; and(v) whether the two chromosomal breaks responsible for the aberration occur on the same side or on opposite sides of a single centromere, or if the two breaksoccur on different chromosomes.a. Reciprocal translocationb. Paracentric inversionc. Small tandem duplicationd. Robertsonian translocatione. Pericentric inversionf. Large deletion
Chapter 5 Solutions
GENETIC ANALYSIS: INTEGRATED - ACCESS
Ch. 5 - For parts a, b, and c, draw a diagram illustrating...Ch. 5 - 5.2 In a diploid species of plant, the genes for...Ch. 5 - A pure-breeding tall plant producing oval fruit as...Ch. 5 - 5.4 Genes E and H are syntenic in an experimental...Ch. 5 - In tomato plants, purple leaf color is controlled...Ch. 5 - 5.6 In Drosophila, the map positions of genes are...Ch. 5 - 5.7 Genes A, B, and C are linked on a chromosome...Ch. 5 - Gene G recombines with gene T at a frequency of...Ch. 5 - Genes A, B, C, D, and E are linked on a...Ch. 5 - Syntenic genes can assort independently. Explain...
Ch. 5 - 5.11 The recombination frequency between linked...Ch. 5 - On the DrosophilaX chromosome, the dominant allele...Ch. 5 - Researchers cross a corn plant that is pure -...Ch. 5 - 5.14 syndrome is an autosomal disorder affecting...Ch. 5 - 5.15 Three dominant traits of corn seedlings,...Ch. 5 - 5.16 In a diploid plant species, an with the...Ch. 5 - Prob. 17PCh. 5 - The Rh blood group in humans is determined by a...Ch. 5 - 5.19 Genetic linkage mapping for a large number of...Ch. 5 - 5.20 with the genotype form tetrads in the...Ch. 5 -
Gene and gene are genetically linked. Answer...Ch. 5 -
T. H. Morgan’s data on eye color and wing form,...Ch. 5 - Prob. 23PCh. 5 -
The boss in your laboratory has just heard of a...Ch. 5 - In rabbits, chocolate-colored fur (w+) is dominant...Ch. 5 - Prob. 26PCh. 5 - 5.27 In tomatoes, the allele for tall plant height...Ch. 5 - 5.28 Neurofibromatosis is an autosomal dominant...Ch. 5 - A 2006 genetic study of a large American family...Ch. 5 - 5.30 A experiment examining potential genetic...Ch. 5 - A genetic study of an early onset form of heart...Ch. 5 - In experiments published in 1918 that sought to...Ch. 5 - DNA sequence for 10 individuals are Identify the...Ch. 5 - 5.34 The accompanying pedigree below shows a...Ch. 5 - 5.35 Based on previous family studies, an...Ch. 5 - Divide a clean sheet of paper into four quadrant...Ch. 5 - 5.37 For six genes known to be linked on chromosme...
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- Human sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?arrow_forwardIn the haploid yeast Saccharomyces cerevisiae, the twomating types are known as MATa and MATα. You cross apurple (ad-) strain of mating type a and a white (ad+)strain of mating type α. If ad- and ad+ are alleles of onegene, and a and α are alleles of an independently inherited gene on a separate chromosome pair, what progenydo you expect to obtain? In what proportions?arrow_forwardIn Figure 4-3, would there be any meiotic products thatdid not undergo a crossover in the meiosis illustrated? Ifso, what colors would they be in the color conventionused?arrow_forward
- Though an individual with abberations such as Robertsonian translocation may be phenotypically normal, they can generate gametes through meiosis that have atypical organizations of chromosomes, resulting in recurrent fetal abnormalities or miscarriages. Why, despite these Robertsonian translocations, are affected cells still able to generate typical gametes through meiosis?arrow_forwardA diploid species with 44 chromosomes (i.e., 22 per set) is crossedto another diploid species with 38 chromosomes (i.e., 19 per set).How many chromosomes are produced in an allodiploid orallotetraploid from this cross? Would you expect the offspring tobe sterile or fertile?arrow_forwardA diploid (2n) trihybrid individual with the genotype EeFfGg can make eight genetically different gametes. Loci E/e and F/f are on chromosome 1 and locus G/g is on chromosome 2. Explain how a gamete containing the alleles e, f and g may be produced by meiosis. Refer specifically to meiotic events occurring during Prophase I, Metaphase I, Anaphase I and Anaphase II. (NB: remember to refer to the organism above).arrow_forward
- A 2n=4 plant is heterozygous at two genes, one controlling plant height (T = tall, t= short) and one controlling disease resistance (D = resistant, d = susceptible). The plant height gene is located on one chromosome, and the disease resistance gene is located on the other chromosome. In the cells below, draw to two possible arrangements of the chromosomes at metaphse I of meiosis. Hint: look at Figure 2.17 in your textbook for an example of how chromosomes can be arranged at metaphase I. Be sure to label the alleles present at the genes on the two chromosomes in each drawing. 00arrow_forwardSuppose that meiosis occurs in the transient diploid stageof the cycle of a haploid organism of chromosome number n. What is the probability that an individual haploidcell resulting from the meiotic division will have a complete parental set of centromeres (that is, a set all fromone parent or all from the other parent)?arrow_forwardMeiotic nondisjunction is much more likely than mitotic nondisjunction.Based on this observation, would you conclude that meioticnondisjunction is usually due to nondisjunction during meiosisI or meiosis II? Explain your reasoning?arrow_forward
- In a vial of Drosophila, a research student noticedseveral female flies (but no male flies) with bag wingseach consisting of a large, liquid-filled blister insteadof the usual smooth wing blade. When bag-wingedfemales were crossed with wild-type males, 1/3 of theprogeny were bag-winged females, 1/3 were normalwinged females, and 1/3 were normal-winged males.Explain these results.arrow_forwardAn individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X Q. Diagram the alternate, adjacent-1, and adjacent-2 segregation patterns in anaphase I of meiosis.arrow_forwardGenes A and B are on different chromosomes. An individual has the genotype: AaBb You sequence two gametes produced by this individual and find one gamete has the genotype AB, and one has the genotype Ab. How can this one individual (genotype AaBb) produce two gametes with different genotypes (AB or Ab)? Your answer should describe a specific process which occurs during meiosis. At what stage of meiosis does this process occur?arrow_forward
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