Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Question
Chapter 50, Problem 15TYK
Summary Introduction
To review:
The experiment would convince that the human BCL2 protein is functional homologous to the worm CED-9 protein.
Introduction:
The Drosophila members of the Bcl-2 gene family whose function is important for programmed cell death. The Bcl-2 family of proteins has grown to include more than twenty members of death-suppressing and promoting molecules found in the genomes of worms, mammals, viruses, and flies. Likewise, cell death abnormality gene 9 (CED-9), is a gene found in Caenorhabditis elegans that inhibits or represses programmed cell death (apoptosis). It is also known as apoptosis regulator CED-9.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
What is an explanation for the similarities between genes in yeasts,nematodes, and mammals that control apoptosis?
Exposing C. elegans to an RNAi molecule homologous to a non-protein-coding RNA gene resulted in the worms’ inability to respond to touch. What predictions could you make about the function of that gene in development?
a. Explain how you could use worms transformedwith myo-2::GFP to find mutations that disrupt thestructure of the pharynx. How would the presenceof the transgene facilitate the mutant screen?b. Nematodes homozygous for loss-of-function mutations in a gene called pha-4 have no detectablepharyngeal structures. How could you use myo2::GFP to determine if pha-4 is a master regulatory gene that directs development of the pharynxin a manner similar to the way Pax-6/eyeless controls eye development?
Chapter 50 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 50.1 - Prob. 1SBCh. 50.1 - Prob. 2SBCh. 50.2 - Prob. 1SBCh. 50.2 - Prob. 2SBCh. 50.2 - Prob. 3SBCh. 50.3 - Prob. 1SBCh. 50.3 - Prob. 2SBCh. 50.4 - Prob. 1SBCh. 50.4 - Prob. 2SBCh. 50.5 - Prob. 1SB
Ch. 50.5 - Prob. 2SBCh. 50.5 - Prob. 3SBCh. 50 - Prob. 1TYKCh. 50 - Prob. 2TYKCh. 50 - Prob. 3TYKCh. 50 - Prob. 4TYKCh. 50 - Prob. 5TYKCh. 50 - Prob. 6TYKCh. 50 - Prob. 7TYKCh. 50 - In the development of the female sex organs: a....Ch. 50 - In the embryonic development of the eye: a. the...Ch. 50 - Prob. 10TYKCh. 50 - Discuss Concepts Experimentally, it is possible to...Ch. 50 - Discuss Concepts Developmental biologist Lewis...Ch. 50 - Discuss Concepts Arguably, in sexually reproducing...Ch. 50 - Prob. 14TYKCh. 50 - Prob. 15TYKCh. 50 - Prob. 16TYKCh. 50 - Prob. 1ITDCh. 50 - Prob. 2ITDCh. 50 - Prob. 3ITDCh. 50 - Prob. 4ITD
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Design a hypothetical experiment to determine the role of microtubules in gamete nuclear migration during fertilization of a fruit fly Drosophila melanogaster.arrow_forwardIf a fertilized Drosophila egg is punctured at the anterior end and a small amount of cytoplasm is allowed to leak out, what will be the most likely effect on the development of the fly embryo?arrow_forwardIf you observed fruit flies with the following developmental abnormalities, would you guess that a mutation has occurred in a segmentation gene or a homeotic gene? Explain your guess. A. Three abdominal segments were missing. B. One abdominal segment had legs. C. A fly with the correct number of segments had two additional thoracic segments and two fewer abdominal segments.arrow_forward
- Which of the following is NOT an example of cell migration as a part of cell differentiation? A. Mesenchyme cells forming mesoderm during gastrulation B. Primitive streak formation in a chick embryo C. Concentration of protein complexes during cleavage D. Convergent extension to elongate the archenteron in the sea urchinarrow_forwardI am confused about how stem cell transplants works. If you put a semi differentiated tadpole nucleus in a denucleated egg cell, it’ll develop into a fully formed tadpole, but if you put a fully differentiated tadpole nucleus, it won’t (because the genes have already been expressed in a way where the cytoplasmic determinants cannot operate to the fullest). Then how come in stem cell transplants, you use adult nucleuses that are already developed and transplant them into the denucleated egg cells?arrow_forwardThe homeotic mutation Antennapedia causes mutant Drosophila to have legs in place of antennae and is a dominant gain of-function mutation. What are the properties of such mutations?How does the Antennapedia gene change antennae into legs?arrow_forward
- Another way to study the role of proteins (e.g., transcription factors) that function in development is to microinject the mRNA that encodes a protein, or the purified protein itself, into an oocyte or embryo, and then determine how this affects the subsequent development of the embryo, larva, and adult. For example, if Bicoid protein is injected into the posterior region of an oocyte, the resulting embryo will develop into a larva that has anterior structures at both ends. Based on your understanding of the function of each developmental gene, what would be the predicted phenotype if the following proteins or mRNAs were injected into normal oocytes? A. Nanos mRNA injected into the anterior end of an oocyte B. Antp protein injected into the posterior end of an embryo C. Toll mRNA injected into the dorsal side of an early embryoarrow_forwardThe crawling displayed by many embryonic cells in animals involves distinct events. Which of the following sequences places these events in correct order? protrusion at the cell's leading edge, attachment of protrusion, pulling the cell forward, release and retraction of trailing edge attachment of protrusion, pulling the cell forward, protrusion at the cell's leading edge, release and retraction of trailing edge release and retraction of protrusion, protrusion at the cell's leading edge, attachment of trailing edge, pulling the cell forward pulling the cell forward, release and retraction of protrusion, protrusion at the cell's leading edge, attachment of trailing edge attachment of protrusion, protrusion at the cell's leading edge, pulling the cell forward, release and retraction of trailing edgearrow_forwardWhich of the following best describes the concept of cell differentiation during the development of a multicellular organism? A. During development, all of the genes in the embryo's cells are expressed at first, but fewer and fewer are expressed as time proceeds. B. During development, different sets of genes are deleted from different cell types so that at the end of development, each cell has only the genes it needs. C. During development, different cells become specialized to have different phenotypes even though they all originated from the same cell. ..arrow_forward
- The MyoD gene in mammals plays a role in skeletal muscle-cell differentiation, whereas the Hox genes are homeotic genes that play a role in the differentiation of particular regions of the body. Explain how the functions of these genes are similar and different.arrow_forwardYou isolate a glp-1 mutation of C. elegans and discoverthat the DNA region encoding the spatial control region(SCR) has been deleted. What will the GLP-1 protein expression pattern be in a four-cell embryo in mutant heterozygotes? In mutant homozygotes?arrow_forwardX-Chromosome Inactivation in mammals results in the formation of what structures that can be seen in the nucleus? a Spliceosomes b Mitochondria c Nuclear Envelope d Barr Bodies e Nuclear Colorationsarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Embryology | Fertilization, Cleavage, Blastulation; Author: Ninja Nerd;https://www.youtube.com/watch?v=8-KF0rnhKTU;License: Standard YouTube License, CC-BY