Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 50.4, Problem 5R
Summary Introduction
To review:
The mechanism by, which pyruvate and lactate support continuing glycolysis.
Introduction:
Muscles do not get enough oxygen when the person is exercising. In this situation, the muscles produce pyruvate and lactate in addition to small amounts of adenosine triphosphate (ATP). The pyruvate and lactate produced in the muscles can be again utilized in glycolysis.
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Life: The Science of Biology
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- ATP for muscle contraction can be provided by ______. a. aerobic respiration b. lactate fermentation c. transfer of a phosphate from creatine phosphate d. all of the abovearrow_forwardStudy Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.arrow_forwardBetween two extremes. What is the role of a thioester in the formation of ATP in glycolysis?arrow_forward
- As early as the 1930s, it was known that frog muscles could still contract when glycolysis was inhibited. Where did the ATP come from to drive these contractions?arrow_forwardWhy does epinephrine stimulate glycolysis? I know why epinephrine stimulates glycogenolysis which is to release glucose stores. But epinephrine stimulating glycolysis seems counterintuitive as it would synthesize less glucose and more pyruvate?arrow_forwardGluconeogenesis is not a mere reversal of glycolysis, explain?arrow_forward
- when pyruvate and lactate is producearrow_forwardCH3CH2OH + NAD+ --> CH3CHO + NADH +H+ Explain how this reaction inhibits the production of pyruvate from lactate. Why does this lead to low blood glucose levels? please and thank youarrow_forwardwhat effect would an increase in glucose typically have on the activity of glycogen synthasearrow_forward
- In angiogenic endothelial cells, pyruvate is converted to lactate (generating 2 ATP per glucose) rather than being completely oxidized (which would generate ~32 ATP by oxidative phosphorylation). Explain why angiogenic cells generate ATP anaerobically.arrow_forwardGlycolysis can occur under both aerobic and anaerobic conditions. Why is glycolysis called an anaerobic pathway?arrow_forwardA glucose molecule with its 3rd carbon radiolabelled underwent glycolysis. Which carbon atom in the resultant pyruvate will show radioactivity?arrow_forward
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