Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 51.1, Problem 2EQ
CoreSKILL » Approximately how many times more often did deleterious mutations persist in the asexually reproducing populations compared to the sexually reproducing ones?
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Q1: Why is an insertion or a deletion in a gene more likely to alter the protein product than a substitution, such as A for C, would? Q2: Which would you expect to have more impact on an organism: a point mutation as shown here, or the insertion or deletion of a whole chromosome (discussed in Chapter 8)? Q3: Which mechanisms in a cell prevent mutations?
What is the basis for the lowfrequency of errors in DNA replicationobserved in all cells? Is this the bestthat cells can do given the speed ofreplication and the limits of moleculardiffusion? Was this mutation rateselected in evolution to provide geneticvariation?
Next-generation sequencing reveals that six new mutations have occurred in the coding regions of genes in an individual diploid fly. If the coding regions of this fly comprise 100 million nucleotides per haploid genome, what is the mutation rate per nucleotide?
Chapter 51 Solutions
Biology
Ch. 51.1 - CoreSKILL How did Paland and Lynch test the...Ch. 51.1 - CoreSKILL Approximately how many times more often...Ch. 51.1 - Prob. 3EQCh. 51.3 - Prob. 1CSCh. 51.4 - Prob. 1CSCh. 51.4 - Prob. 2CSCh. 51.4 - Prob. 1CCCh. 51 - Prob. 1TYCh. 51 - Which is considered an advantage of sexual...Ch. 51 - Prob. 3TY
Ch. 51 - Prob. 4TYCh. 51 - Prob. 5TYCh. 51 - Prob. 6TYCh. 51 - A major function of FSH is to a. stimulate the...Ch. 51 - During the human ovarian cycle, ovulation is...Ch. 51 - Prob. 9TYCh. 51 - Prob. 10TYCh. 51 - Prob. 1CQCh. 51 - Prob. 2CQCh. 51 - Prob. 3CQCh. 51 - Prob. 1COQCh. 51 - Describe the events of the ovarian and uterine...
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- Discuss the sequencing technology used to resolve the human genome in 2005, its significant advantages and limitations?arrow_forwardPlease help with all of these! thank you so much! Neutral regions of a species’ genome that are distant from any selected sites have apairwise diversity (?) of 0.01. Other regions of the genome have reduced genetic variation,and selective sweeps could be responsible for the reduction. Assume that selective sweepshappen at a rate of 10^-10 per bp, and they take 500 generations to reach fixation. Therecombination rate in regions where selective sweeps might occur is 10^-8 per bp. Theeffective population size of the species is 10^5. A. Find the expected genetic diversity (? per bp) in regions where selective sweepsmight be occurring.B. Find the deleterious mutation rate (per bp) that would be required to produce anequivalent reduction in genetic diversity as a result of background selection (BGS)?Assume the same recombination rate as above.arrow_forwardBased on MS- LS3-1 Can you make a model that shows how blue eyes originated? Can you include genes, chromosomes, traits, proteins, and organisms? Can you Include a Punnett Square to show how this trait could be passed on to the next generation?arrow_forward
- Question:- Which characteristics would you expect to be indicativeof horizontal gene transfer?T / F A significant change in %GC in part of the genome of an organismT / F Deletions of gene in the genomeT / F An insertion of a stretch of DNA when aligning sequences from closely related speciesT / F Missing genomic DNA sequences when aligning sequences from closely related speciesT / F Duplications of genes in parts of the genomearrow_forwardQ5. In lab 6, you will set up a PCR reaction to yield amplified DNA products of the rpo B(RNA polymerase B) and 16s rRNA genes. In lab 7, you will set up a sequencing reaction using about 40 ng of these PCR products that you will then add a sequencing primer to the sequencing reaction. If a sequencing reaction is set up with a 100-fold excess of primer to the PCR-amplified DNA product you want to sequence, calculate the number of sequencing primers you will need to add to this sequencing reaction. To perform this calculation, assume your 40 ng sample of double stranded DNA is 4,000 base-pairs (bp) long. Using these two variables of your PCR product [length (in bp) and amount (in g, grams)], you can calculate the number of DNA molecules being sequenced with two conversion factors using the formula below: The average weight of 1 bp is approximately ~650 (g/mole)/bp Avogadro’s number which is 6.02 X 1023 molecules/mole The easiest way to solve this problem is to figure out how much one…arrow_forwardIn a sequence encompassing 99.4 percent of theeuchromatic regions of human chromosome 1, Gregoryet al. [(2006) Nature 441:315–321] identified 3141 genes. Q: How does one identify a gene within a raw sequence of bases in DNA?arrow_forward
- James Noonan and his colleagues (J. Noonan et al. 2005. Science 309:597–599) set out to study the genome sequence of an extinct species of cave bear. They extracted DNA from 40,000-year-old bones from a cave bear and used a metagenomic approach to isolate, identify, and sequence the cave-bear DNA. Why did they use a metagenomic approach when their objective was to sequence the genome of one species (the cave bear)?arrow_forwardIn a sequence encompassing 99.4 percent of theeuchromatic regions of human chromosome 1, Gregoryet al. [(2006) Nature 441:315–321] identified 3141 genes. Q: What features of a genome are used to verify likelygene assignments?arrow_forwardHow many potential evolutionary paths are there for anallele to evolve six different mutations? Seven differentmutations? Ten different mutations?arrow_forward
- 12e which genes that are normally found in a lambda genome would be deleted in your lambda vector? briefly explain why those lambda genes are normally delete it from your lambda phage being used as cloning vectors.arrow_forwardMAKE CONNECTIONS Mutagens are chemical andphysical agents that induce mutations in DNA (seeConcept 17.5). How does reduced ozone concentrationin the atmosphere increase the likelihood of mutationsin various organisms?arrow_forward27. Which term describes any ancient remains, impressions, or traces of an organism or traces of its activity that have been preserved in rocks or other mineral deposits in Earth's crust? a. analogous feature b. homologous feature c. mutation d. fossiarrow_forward
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