EBK BIOLOGY
5th Edition
ISBN: 9780100667976
Author: Maier
Publisher: YUZU
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Chapter 6, Problem 11LTB
Summary Introduction
To define:
The term protooncogene and oncogene.
Introduction:
Cancer is a disease characterized by abnormal cell division. It occurs when cells in a region of the body proliferates in an uncontrolled manner, the excess tissue that develops is called a tumor or neoplasm. The main cause of the cancer is the presence of the oncogenes in the cells.
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Describe the changes that can convert a proto-oncogene into an oncogene.
Distinguish between proto-oncogene and oncogene.
Describe the relationship between proto-oncogenes and oncogenes.
Chapter 6 Solutions
EBK BIOLOGY
Ch. 6 - Prob. 1LTBCh. 6 - Prob. 2LTBCh. 6 - A cell that begins mitosis with 46 chromosomes...Ch. 6 - The centromere is a region at which ___________....Ch. 6 - Prob. 5LTBCh. 6 - At metaphase of mitosis, ___________. the...Ch. 6 - Sister chromatids ___________. are two different...Ch. 6 - DNA polymerase ___________. attaches sister...Ch. 6 - Prob. 9LTBCh. 6 - Prob. 10LTB
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- Describe the general functions of oncogenes.arrow_forwardDescribe what an oncogene, a proto-oncogene, and atumor suppressor gene do.arrow_forwardIdentify two genetic mechanisms whereby proto-oncogenes can become overexpressed. Select the two mechanisms. Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed.Select the two mechanisms. 1) alterations in chromatin structure 2) a gain-of-function alteration 3)modification of proto-oncogenes products 4)mutations that result in an abnormal protein product 5)mutations within gene-regulatory regionsarrow_forward
- Describe Oncogene is responsible forarrow_forwardDescribe three types of genetic changes that commonly convert aproto-oncogene to an oncogene. Explain how the genetic changesare expected to alter the activity of the gene product.arrow_forwardWhat types of functions are performed by the products of proto-oncogenes?arrow_forward
- What is the function of a proto-oncogene?arrow_forwardexplain Translocations that generate oncogenesarrow_forwardWhat is a proto-oncogene? What are the typical functions of proteinsencoded by proto-oncogenes? At the level of protein function,what are the general ways that proto-oncogenes can beconverted to oncogenes?arrow_forward
- describe the relationship between a proto-oncogene and an oncogene, and explain how one arises from the other. Explain how a mutation in the EGF receptor, or in a GTP- binding protein, can lead to unregulated cell division.arrow_forwardHow might overexpression of proto-oncogenes lead to abnormal cellular proliferation?arrow_forwardName the roles that Anaphase Promoting Complex protein plays.arrow_forward
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