WHAT IS LIFE ACHIEVE ACCESS ONLY >I<
5th Edition
ISBN: 9781319487317
Author: PHELAN
Publisher: INTER MAC
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Chapter 6, Problem 8MC
Summary Introduction
Introduction:
Mutations can be of three types – additions, deletions and substitution.
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How would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicing
Which type of mutation would expect would have no effect on a protein coding gene in eukaryotes?
a.a single base substitution that creates a splice site mutation
b.a single base substitution that creates a synonymous mutation
c.a single base deletion that creates a frameshift near the 3' end of the open reading frame
d.a single base substitution that creates a non-conservative missense mutation
e.a single base substitution that creates a conservative missense mutation
Could a frameshift mutation result in the production of a larger than wild type protein?
A.Yes, but it’s likely only if the frameshift occurs early in the coding sequence.
B.Yes, but it’s likely only if the frameshift occurs late in the coding sequence.
C.Yes, by producing a longer than normal transcript
D.Yes, by producing larger than normal Okazaki fragments.
E.No, frameshift always results in the occurrence of STOP codons and premature termination of translation
Chapter 6 Solutions
WHAT IS LIFE ACHIEVE ACCESS ONLY >I<
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which of the following mutations would have the greatest negative impact on the protein product of a gene? A. a single base deletion close to the end of the coding region of a gene. B. a single base insertion near the start of the coding region of the gene C. a base-pair substitution D. a deletion of three bases near the middle of the genearrow_forwardWhy might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA? a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product. b. If the mutation occurs in the exon, it will not affect the gene product. c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may affected. O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc affect the gene product. O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product. OLIE STIC N 1Aarrow_forwardThere are 61 mRNA codons that specify an amino acid, but only 45 tRNAs. This is best explained by the fact that A. some tRNAs have anticodons that recognize two or more different codons. B. the rules for base pairing between the third base of a codon and tRNA are flexible. C. many codons are never used, so the tRNAs that recognize them are dispensable. D. A and B only E. A, B, and Carrow_forward
- If a mutation deletes the promoter in a eukrayotic gene, which of the following most accurately describes its consequence? A. There will be no mRNA or polypeptide made. B. The mRNA will be made but no polypeptide is made. C. The mRNA will not be processed properly. D. Nothing will happen. It is a silent mutation.arrow_forwardWhich of the following would probably cause the most severe damage to a gene's expression and phenotype a. A missense mutation changing the first methionine codon to an arginine codon. b. A deletion of a base in the 455th codon of a 456-amino acid protein. c. Alteration of a UGG codon to a UGA codon at position 324 of a 324 amino acid protein. d. Mutation of a GUC codon (valine) to a GUU codon (valine).arrow_forwardWhich of the following statements about RNA processing in eukaryotes is INCORRECT? A. The excision of introns from pre-mRNA is the only modification required to produce a mature mRNA. B. A protein/RNA complex is used to remove introns from the pre-mRNA. C. A poly A tail is added on to the 3′ end of the mRNA. D. A 7-methylguanosine cap is added on to the 5′end of the mRNA. E. Modification occurs in the nucleus.arrow_forward
- Which of the following amino acid changes could result from a mutation that changed a single base? For each change that could result from the alteration of a single base, determine which position of the codon (first, second, or third nucleotide) in the mRNA must be altered for the change to result. a. Leu → Gln b. Phe → Ser c. Phe → Ile d. Pro → Ala e. Asn → Lys f. Ile → Asnarrow_forwardConsider the mRNA base sequence 5' ACC CAC 3'. what dipeptide is coded for by this mRNA? * A. Asparagine- Histidine B. Lysine -Serine C. Aspartic Acid - Histidine D. Lysine-Glysine Look at the following sequence, " THE FAT CAT ATE THE CAT" Remove the first "H" and regroup the letters in group of three. What type of mutation? * A. Deletion-Frameshift B. Insertion- frameshift C. Substitution-Deletion D. Substitution-Insertion Which of the following types of RNA is involved in the transcription phase of protein synthesis? * A. rRNA B. tRNA C. hnRNA D. no correct response A tRNA molecule has the anticodon 5' AAG 3', with which mRNA codon will this anticodon interact? * A. 5' AAG 3 B. 5' CUU 3' C. 3' GAA 5'…arrow_forwardConsider the mRNA base sequence 5' ACC CAC 3'. what dipeptide is coded for by this mRNA? * A. Asparagine- Histidine B. Lysine -Serine C. Aspartic Acid - Histidine D. Lysine-Glysine Look at the following sequence, " THE FAT CAT ATE THE CAT" Remove the first "H" and regroup the letters in group of three. What type of mutation? * A. Deletion-Frameshift B. Insertion- frameshift C. Substitution-Deletion D. Substitution-Insertion Which of the following types of RNA is involved in the transcription phase of protein synthesis? * A. rRNA B. tRNA C. hnRNA D. no correct response A tRNA molecule has the anticodon 5' AAG 3', with which mRNA codon will this anticodon interact? * A. 5' AAG 3 B. 5' CUU 3' C. 3' GAA 5'…arrow_forward
- Explain point mutations and frameshift mutations. Which is more apt to disrupt the structure and or function of a protein coded for by a gene? Why?arrow_forwardThe original DNA base sequence is 5’-AGCGTTACCGT-3’; a mutation in the DNA strand results in the base sequence 5’-AGGCGTTACCGT-3’. What can you conclude about the mutation? A. It is a frameshift mutation. B. It is a silent mutation. C. It is a deleterious mutation. D. It may result in a single amino acid change in the protein being coded for by this base sequence.arrow_forwardWhich type of point mutation does not affect the resulting protein? a deletion b missense mutation c silent mutation d nonsense mutationarrow_forward
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY