Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
4th Edition
ISBN: 9781260159363
Author: Martin, Terry R., Prentice-craver, Cynthia
Publisher: McGraw-Hill Publishing Co.
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Chapter 62, Problem 3.5A

Color blindness is an example of X-linked inheritance. Hemophilia is another example of X-linked inheritance, also from a recessive allele (h). The dominant allele (H) determines whether the person possesses normal blood clotting. A person with hemophilia has a permanent tendency for hemorrhaging due to a deficiency of one of the clotting factors (VIII—antihemophilic factor). Determine the offspring from a cross of a mother who is a carrier (heterozygous) for the disease and a father with normal blood coagulation.

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I will be adding two questions here because I asked two of the same questions twice by accident earlier.  A man and a woman do not have hemophilioa, but the womans father did. (Hemophilia is X-linked recessive). a) What is the probability that they will have a child with hemophilia? b) Is it possible for any of their daughters to be affected? Explain. A cross between a horse homozygous for red hair and a horse homozygous for white hair results in offspring with the coat colour called roan. When you look at the fur of the roan offspring you see both red and white hairs. What type of inheritance best explains this?  a) blending inheritance b)codominance c)incomplete codominance d)multiple alleles
Hemophilia is another example of an X-linked disease caused when a recessive allele (Xh) is expressed. If a normal male reproduces with a heterozygous normal female, what are the expected genotypes and phenotypes? Will any of their daughters develop hemophilia?
The following pedigree describes the inheritance of Lesch-Nyhan syndrome, an x-linked recessive disease. Affected individuals are shaded. what is the probability, that the indicated child (IV.1) will be affected by Lesch-Nyhan syndrome? show solution
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