Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
12th Edition
ISBN: 9780134811390
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Textbook Question
Chapter 7, Problem 27ESP
When the cloned cat Carbon Copy (CC) was born (see the Now Solve This question on p. 161), she had black patches and white patches, but completely lacked any orange patches. The knowledgeable students of genetics were not surprised at this outcome. Starting with the somatic ovarian cell used as the source of the nucleus in the cloning process, explain how this outcome occurred.
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Chapter 7 Solutions
Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
Ch. 7 - Campomelic dysplasia (CMD1) is a congenital human...Ch. 7 - Carbon Copy (CC), the first car produced from a...Ch. 7 - Gender is someones conscious and unconscious...Ch. 7 - Gender is someones conscious and unconscious...Ch. 7 - HOW DO WE KNOW? In this chapter, we have focused...Ch. 7 - Review the Chapter Concepts list on p. 151. These...Ch. 7 - Distinguish between the concepts of sexual...Ch. 7 - Contrast the XX/XY and XX/X0 modes of sex...Ch. 7 - Describe the major difference between sex...Ch. 7 - How do mammals, including humans, solve the dosage...
Ch. 7 - The phenotype of an early-stage human embryo is...Ch. 7 - What specific observations (evidence) support the...Ch. 7 - Describe how nondisjunction in human female...Ch. 7 - An insect species is discovered in which the...Ch. 7 - When cows have twin calves of unlike sex...Ch. 7 - An attached-X female fly, XXY (see the Insights...Ch. 7 - Assume that on rare occasions the attached X...Ch. 7 - It has been suggested that any male-determining...Ch. 7 - What is a Barr body, and where is it found in a...Ch. 7 - Indicate the expected number of Barr bodies in...Ch. 7 - Define the Lyon hypothesis.Ch. 7 - Can the Lyon hypothesis be tested in a human...Ch. 7 - Predict the potential effect of the Lyon...Ch. 7 - Cat breeders are aware that kittens expressing the...Ch. 7 - In mice, the Sry gene (see Section 7.2) is located...Ch. 7 - The genes encoding the red-and...Ch. 7 - What is the role of the enzyme aromatase in sexual...Ch. 7 - In the wasp Bracon hebetor, a form of...Ch. 7 - The Amami spiny rat (Tokudaia osimensis) lacks a Y...Ch. 7 - In mice, the X-linked dominant mutation Testicular...Ch. 7 - When the cloned cat Carbon Copy (CC) was born (see...Ch. 7 - In reptiles, sex determination was thought to be...Ch. 7 - In chickens, a key gene involved in sex...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- In 1997, Dolly the sheep was cloned by a technique called somatic-cell nuclear transfer (or nuclear-transfer cloning). A nucleus from an adult mammary cell was transferred into an egg from which the nucleus had been removed. The egg was allowed to divide several times in culture, then the embryo was transferred to a surrogate mother who gave birth to Dolly. Dolly died in 2003 after mating and giving birth herself to viable offspring. What does the creation of Dolly tell us about the potential of nuclear material derived from a fully differentiated adult cell? Does the creation of Dolly tell us anything about the potential of an intact, fully differentiated adult cell?arrow_forwardWhen a particular mutagen identified by the Ames testis injected into mice, it causes the appearance of manytumors, showing that this substance is carcinogenic.When cells from these tumors are injected into othermice not exposed to the mutagen, almost all of the newmice develop tumors. However, when mice carryingmutagen-induced tumors are mated to unexposed mice,virtually all of the progeny are tumor free. Why can thetumor be transferred horizontally (by injecting cells)but not vertically (from one generation to the next)?arrow_forwardresearchers have been able to clonemammals by fusing a cell having a diploid nucleus (i.e., a somaticcell) with an egg that has had its nucleus removed.A. With regard to maternal effect genes, would the phenotype ofsuch a cloned animal be determined by the animal that donatedthe egg or by the animal that donated the somatic cell? Explain.B. Would the cloned animal inherit extranuclear traits from theanimal that donated the egg or from the animal that donated thesomatic cell? Explain.C. In what ways would you expect this cloned animal to be similarto or different from the animal that donated the somatic cell? Isit fair to call such an animal a clone of the animal that donatedthe diploid nucleus?arrow_forward
- No. 32 CC (Carbon Copy), the first cat produced from a clone, was created from an ovarian cell taken from her genetic donor, Rainbow. The diploid nucleus from the cell was extracted and then injected into an enucleated (remove the nucleus of) egg. The resulting zygote was then allowed to develop in a petri dish, and the cloned embryo was implanted in the uterus of a surrogate mother cat, who gave birth to CC. Rainbow is a calico cat. CC’s surrogate mother is a tabby (any cat that has a distinctive coat that features stripes, dots, lines or swirling patterns, usually together with a mark resembling an "M" on its forehead). Geneticists were very interested in the outcome of cloning a calico cat, because they were not certain if the cat would have patches of orange and black, just orange or just black. Taking into account the Lyon hypothesis, explain the basis of the uncertainty.arrow_forwardMany cancer cells are immortal and can be cultured in the laboratory for many years. Many of these cell lines have highly active telomerase activities. Why would that affect the ability of cancer cells to sustain growth and cell division?arrow_forwardA normal appearing female infant was identified with a positive newborn screen, linked to chromosome 12. Few years ago, her older sibling had developed profound hypoglycemia, liver failure leading to coma, and subsequent irreparable brain damage, following a viral illness. The sibling was subsequently shown by clinical testing to have the same disorder that this female infant is screened positive for. a. What is the most likely diagnosis? b. What biomarkers would confirm this on the newborn screening process? Describe the mechanism that causes this metabolic defect.arrow_forward
- Not all inherited traits are determined by nuclear genes (i.e., genes located in the cell nucleus) that are expressed during the life of an individual. In particular, maternal effect genes and mitochondrial DNA are notable exceptions. With these ideas in mind, let’s consider the cloning of a sheep (e.g., Dolly). A. With regard to maternal effect genes, is the phenotype of such a cloned animal determined by the animal that donated the enucleatedegg or by the animal that donated the somatic cell nucleus? Explain.arrow_forwardWhy would a mutation in a somatic cell of a multicellular organism not necessarily result in a detectable phenotype?arrow_forwardKnockout mice are mice in which a functional gene or a group of functional genes are rendered nonfunctional by a special technique involving homologous recombination. Predict what happen to knockout mice which have their RAG-1 and RAG-2 genes “removed".arrow_forward
- Explain in detail the meaning of gene fusion. How is this process related to prostate cancer development?arrow_forwardWHIM syndrome is a disease of the immunesystem resulting in warts and frequent infections.The disease is caused by a dominant gain-of-functionmutation in a gene on chromosome 2 called CXCR4.A 38-year-old woman suffering with WHIM syndrome her entire life was suddenly and mysteriouslycured. Genome analysis of her blood precursor cells(stem cells) revealed that many of these cells had achromosome 2 that had undergone chromotripsis—arare (and poorly understood) process where a chromosome is “shattered” into small pieces that are subsequently stitched back together in random order, resultingin many deletions and inversions. Explain howchromotripsis of chromosome 2 in a blood stem cellcould have cured the woman of WHIM syndrome.arrow_forwardTake a look at question 3 in More Genetic TIPS. Let’s suppose amale is heterozygous for two polymorphic sequence-tagged sites.STS-1 exists in two sizes: 211 bp and 289 bp. STS-2 also exists intwo sizes: 115 bp and 422 bp. A sample of sperm was collectedfrom this man, and individual sperm were placed into 30 separatetubes. Into each of the 30 tubes were added the primers that amplifySTS-1 and STS-2, and then the samples were subjected toPCR. The following results were obtained:arrow_forward
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