Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 7, Problem 3P
Summary Introduction

To examine:  Whether the statement “CG islands are thought to have arisen during evolution because they were associated with portions of the genome that remained unmethylated in the germ line” is true or false.

Introduction:

A CG island is a short DNA stretch where the frequency of CG (cytosine followed by guanine) is higher as compared to other sequences. It is also known as CpG island. The cytosine (C) in CG sequence is methylated in inactive genes so as to suppress the gene action. The CG sequence genes are unmethylated in genes that are expressed or located near the promoter regions.

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Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License