Organic Chemistry
Organic Chemistry
3rd Edition
ISBN: 9781119338352
Author: Klein
Publisher: WILEY
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Chapter 7.3, Problem 7CC
Interpretation Introduction

Interpretation:

The possible mechanism should be drawn and identified for the given alkylated molecule of melphalan.

Concept Introduction:

Leaving group: It is a fragment that leaves the chemical compound with pair of electrons in a heterolytic bond cleavage. The SN2 reactivity increases in molecule with better leaving group.

Nucleophile: Donates pair of electrons to positively charged substrate resulting in the formation of chemical bond.

Structure of the substrate plays major role in the reactivity of SN2 reaction. If the substrate is more substituted then the rate of the reaction will becomes slower. Since the mechanism of SN2 reaction proceeds through backside attack on the substrate, it depends on steric factor that if more groups attached near the leaving group the reactivity becomes slower. The SN2 reactivity increases in molecule with better leaving group. The reactivity increases in the order as follows,

Elimination Reaction: It is just reverse reaction of addition where substituent from the given molecule is removed via E1 (the reaction depends only on the substrate involved in the reaction) or E2 (the reaction depends on both of the substituents in the reaction) mechanism.

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Chapter 7 Solutions

Organic Chemistry

Ch. 7.4 - Prob. 9CCCh. 7.5 - Prob. 10CCCh. 7.6 - Prob. 11CCCh. 7.7 - Provide a systematic name for each of the...Ch. 7.7 - Prob. 13CCCh. 7.7 - Prob. 14CCCh. 7.7 - Prob. 15CCCh. 7.7 - Prob. 16CCCh. 7.7 - Prob. 17CCCh. 7.8 - Prob. 3LTSCh. 7.8 - Predict the major and minor products for each of...Ch. 7.8 - Prob. 19PTSCh. 7.8 - Prob. 20ATSCh. 7.8 - Prob. 4LTSCh. 7.8 - Prob. 21PTSCh. 7.8 - Prob. 23CCCh. 7.8 - Prob. 24CCCh. 7.8 - Prob. 5LTSCh. 7.8 - Prob. 25PTSCh. 7.8 - Prob. 26ATSCh. 7.9 - Prob. 6LTSCh. 7.9 - Prob. 27PTSCh. 7.9 - Prob. 28ATSCh. 7.9 - Prob. 29CCCh. 7.9 - Prob. 30CCCh. 7.9 - Prob. 31CCCh. 7.9 - Prob. 32CCCh. 7.9 - Draw all of the expected products for each of the...Ch. 7.10 - Prob. 35CCCh. 7.10 - Prob. 36CCCh. 7.11 - Prob. 7LTSCh. 7.11 - Prob. 37PTSCh. 7.11 - Prob. 38ATSCh. 7.11 - Prob. 39ATSCh. 7.11 - Prob. 40ATSCh. 7.12 - Prob. 41CCCh. 7.12 - Prob. 42CCCh. 7.12 - Prob. 43CCCh. 7.13 - Prob. 8LTSCh. 7.13 - Prob. 44PTSCh. 7.13 - Prob. 45PTSCh. 7.13 - Prob. 46ATSCh. 7 - Prob. 47PPCh. 7 - Prob. 48PPCh. 7 - Prob. 49PPCh. 7 - Prob. 50PPCh. 7 - Prob. 51PPCh. 7 - Prob. 52PPCh. 7 - Prob. 53PPCh. 7 - Prob. 54PPCh. 7 - Prob. 55PPCh. 7 - Prob. 56PPCh. 7 - Prob. 57PPCh. 7 - Prob. 58PPCh. 7 - Prob. 59PPCh. 7 - Prob. 60PPCh. 7 - Prob. 61PPCh. 7 - Prob. 62PPCh. 7 - Prob. 63PPCh. 7 - Prob. 64PPCh. 7 - Prob. 65PPCh. 7 - Prob. 66PPCh. 7 - Prob. 67PPCh. 7 - Prob. 68PPCh. 7 - Prob. 69PPCh. 7 - Prob. 70PPCh. 7 - Prob. 71PPCh. 7 - Prob. 72PPCh. 7 - Predict which of the following substrates will...Ch. 7 - Prob. 74PPCh. 7 - Prob. 75PPCh. 7 - Prob. 76PPCh. 7 - Prob. 77PPCh. 7 - Prob. 78PPCh. 7 - Prob. 79PPCh. 7 - Prob. 80IPCh. 7 - Prob. 81IPCh. 7 - Prob. 82IPCh. 7 - Prob. 83IPCh. 7 - Prob. 84IPCh. 7 - Prob. 85IPCh. 7 - Prob. 87IPCh. 7 - Prob. 88IPCh. 7 - Prob. 89IPCh. 7 - Prob. 90IPCh. 7 - Prob. 91IPCh. 7 - Prob. 92IPCh. 7 - Prob. 94IPCh. 7 - Prob. 95IPCh. 7 - Prob. 96IPCh. 7 - Prob. 97IPCh. 7 - Prob. 98IPCh. 7 - For the following substitution reaction, which...Ch. 7 - Prob. 100IPCh. 7 - Prob. 101IPCh. 7 - Prob. 102CPCh. 7 - Prob. 104CPCh. 7 - Prob. 105CPCh. 7 - When 2-iodobutane is treated with a variety of...
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