Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 9, Problem 11TYK
Discuss Concepts Describe the possible ways in which a G-protein–coupled receptor pathway could become defective and not trigger any cellular responses.
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Chapter 9 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 9.1 - What accounts for the specificity of a cellular...Ch. 9.2 - Prob. 1SBCh. 9.2 - Prob. 2SBCh. 9.3 - Prob. 1SBCh. 9.3 - Prob. 2SBCh. 9.3 - Prob. 3SBCh. 9.3 - Prob. 4SBCh. 9.3 - Prob. 5SBCh. 9.3 - Prob. 6SBCh. 9.4 - What distinguishes a steroid receptor from a...
Ch. 9.4 - By what means does a specific steroid hormone...Ch. 9.5 - Prob. 1SBCh. 9 - In signal transduction, which of the following is...Ch. 9 - Which of the following could not elicit a signal...Ch. 9 - A cell that responds to a signaling molecule is...Ch. 9 - Prob. 4TYKCh. 9 - Prob. 5TYKCh. 9 - Which of the following is incorrect about pathways...Ch. 9 - Which of the following would not inhibit signal...Ch. 9 - Prob. 8TYKCh. 9 - Prob. 9TYKCh. 9 - Prob. 10TYKCh. 9 - Discuss Concepts Describe the possible ways in...Ch. 9 - Discuss Concepts Is providing extra insulin an...Ch. 9 - Discuss Concepts There are molecules called GTP...Ch. 9 - Discuss Concepts Why do you suppose cells evolved...Ch. 9 - How would you set up an experiment to determine...Ch. 9 - Prob. 16TYKCh. 9 - Prob. 1ITDCh. 9 - Prob. 2ITDCh. 9 - Prob. 3ITD
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- Outline the three general means by which binding of a water soluble extracellular chemical messenger to its matching surface membrane receptor brings about the desired intracellular response.arrow_forwardExplain why a peptide (protein) ligand can’t use a receptor inside the cell while an asteroid has no problem using an intracellular receptor.arrow_forwardTAS2R38 codes for a G-protein coupled receptor which contributes to the tasting of PTC. What does this tell you about PTC as a type of ligand? a It is a protein-based ligand that can cross the CM into the cell b It is a lipid based ligand that can cross the CM into the cell c It is a protein-based ligand that requires a second messenger d It is a lipid-based ligand that requires a second messengerarrow_forward
- What are the locations of G-protein coupled receptors in animal cells, and how are they activated?• Describe a protein's activity when it is activated by a G protein.• Describe one method in which a cell's metabolic activity changes as a result of the activation of a G-protein coupled receptor.arrow_forwardA) Please explain what a G protein coupled receptor is. Please explain how G protein interacts with this receptor. B) Please explain the kind of reactions that follow binding a specific ligand to a G protein coupled receptor. What do these reactions do in the cell? C) How do these reactions work in the cell. What is the function of these reactions in the cell? How do the reactions proceed?arrow_forwardIn vesicle based signaling, how is the regulated secretory pathway implicated in synaptic signaling ? Then, apply this information to describe in detail the pathway in which a neurotransmitter is received at the dendrites of one neuron and ultimately leads to the release of new transmitters that activate a second neuron .arrow_forward
- Cell Communications Explain the role of the trans-membrane and the intracellular protein receptors in cell signaling (provide an example of each).arrow_forwardCompare and discuss intergrin and tyrosine kinase signaling pathway . Show the difference and similarities between them interns of receptor ligand binding, signal transduction, changes in gene expression and subsequent cellular responsesarrow_forwardKey features of signal transduction mechanisms are: specificity, amplification, integration and desensitisation. Give an account of how these features apply to G-protein coupled receptor signallingarrow_forward
- Briefly discuss the mechanism in receptor signal transductionarrow_forward. which of the following statements about heterotrimetric G proteins and their receptors is incorrect? A: when GTP binds to the alpha subunit of the G protein, the beta-gamma subunit dissociates from the alpha subunit B: G-protein coupled receptors contain nine transmembrane alpha helices C: binding of arrestin causes removal of the receptor from the membrane D: G protein- coupled receptors may be desensitized by serine phosphorylation I had chosen option A and got it wrong. What is the Correct answer and explain how it is. Also, where did i go wrong in choosing option A?arrow_forwardExplain how a tyrosine kinase (YK) receptor becomes phosphorylated and activated upon ligand binding.arrow_forward
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