Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
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Chapter 9, Problem 12PIAT
QUANTITATIVE The production of ROS can be reduced using drugs that allow protons to freely pass through the inner membrane. The effect of a drug called DNP on the life span of mice is shown in the graph below. Each point represents the death of a single mouse. At what age is the difference in survival between the DNP-treated and the untreated control the greatest?
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Chapter 9 Solutions
Biological Science (6th Edition)
Ch. 9 - Where does the citric acid cycle occur in...Ch. 9 - 2. What does the chemiosmotic hypothesis claim?
a....Ch. 9 - 3. After glucose is fully oxidized by glycolysis,...Ch. 9 - 4. What is the primary function of the reactions...Ch. 9 - Compare and contrast substrate-level...Ch. 9 - If you were to expose cells that are undergoing...Ch. 9 - In step 3 of the citric acid cycle, the enzyme...Ch. 9 - 8. Explain the relationship between electron...Ch. 9 - 9. Cyanide (C=N–) blocks complex IV of the...Ch. 9 - QUANTITATIVE Early estimates suggested that the...
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- State how the below perturbations will affect (or not) an autocell’s ability to survive. Provide your reasoning in each case. (a) Depletion of a substrate that is part of the autocatalytic cycle (b) Formation of a modified product (due to the uptake of a modified substrate) that functions as a receptorarrow_forwardreferred to feedback inhibition as “Goldilocks regulation”. Describe how feedback inhibition keeps a pathway running at just the right level?arrow_forwardLactose transporter of E. coli is a well-studied proton driven cotransporter. It transports one lactose molecule together with one proton into the cell. Calculate the free energy change for transporting one more of protons into the cell? Membrane potential is -50 mV (inside is negative) and the pH = 7.2 inside the cell and the pH = 4.0 outside the cell. Temperature is 37 degrees celsius (310K). Remeber to convert pH to (H+) and express your answer as kJ/mol.arrow_forward
- draw an arrow pushing mechanism of the reaction catalyzed by COX enzymes What aspirin do to one of the activities and how does the structural change that aspirin induces explain this change in activity? use PYMOL or chimera software to explain your answerarrow_forwardCalculate the energy cost (free-energy change) of pumping Ca2+ from thecytosol, where its concentration is about 1.0 × 10−7 M, to the extracellularfluid, where its concentration is about 1.0 mM. Assume a temperature of 37°C (body temperature in a mammal) and a standard transmembrane potentialof 50 mV (inside negative) for the plasma membrane.arrow_forwardAnimal cells utilize rapid increases in cytosolic Ca++ ion concentration to respond to certain extracellular signals. This requires keeping the cytosolic Ca++ ion concentration very low in the absence of signal (when the cell is “at rest”) and increasing the cytosolic Ca++ ion concentration when a signal is detected. Propose a mechanism by which the action of Ca++ transport proteins in the plasma membrane can account for the reversibility of Ca++ levels in the cytosol. Be sure to indicate whether active or passive transport is involved as well as the type of transport protein (channel or carrier) responsible.arrow_forward
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