Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 9, Problem 31CTQ
What is a possible result of a mutation in a kinase that controls a pathway that stimulates cell growth?
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What is the function of a protein kinase? What amino acids are often phosphorylated by kinases?
What would be the effect of inhibiting the kinase?
What is the purpose of the Map Kinase Cascade?
Chapter 9 Solutions
Biology 2e
Ch. 9 - Figure 9.8 HER2 is a receptor tyrosine kinase. In...Ch. 9 - Figure 9.10 In certain cancers, the GTPase...Ch. 9 - Figure 9.17 Which of the following statements...Ch. 9 - Figure 9.18 What advantage might biofilm...Ch. 9 - What property prevents the ligands of cell-surface...Ch. 9 - The secretion of hormones by the pituitary gland...Ch. 9 - Why are ion channels necessary to transport ions...Ch. 9 - Endocrine signals are transmitted more slowly than...Ch. 9 - A scientist notices that when she adds a small,...Ch. 9 - Where do DAG and IP3 originate? They are formed by...
Ch. 9 - What property enables the residues of the amino...Ch. 9 - Histamine binds to the H1 G-protein-linked...Ch. 9 - A scientist observes a mutation in the...Ch. 9 - What is the function of a phosphatase? A...Ch. 9 - How does NF-kB induce gene expression? A small,...Ch. 9 - Apoptosis can occur in a cell when the cell is...Ch. 9 - What is the effect of an inhibitor binding an...Ch. 9 - How does PKC’s signaling role change in response...Ch. 9 - A scientist notices that a cancer cell line fails...Ch. 9 - Which type of molecule acts as a signaling...Ch. 9 - Quorum sensing is triggered to begin when...Ch. 9 - A doctor is researching new ways to treat biofilms...Ch. 9 - What is the difference between intracellular...Ch. 9 - How are the effects of paracrine signaling limited...Ch. 9 - What are the differences between internal...Ch. 9 - Cells grown in the laboratory are mixed with a dye...Ch. 9 - Insulin is a hormone that regulates blood sugar by...Ch. 9 - The same second messengers are used in many...Ch. 9 - What would happen if the intracellular domain of a...Ch. 9 - If a cell developed a mutation in its MAP2K1 gene...Ch. 9 - What is a possible result of a mutation in a...Ch. 9 - How does the extracellular matrix control the...Ch. 9 - A scientist notices that a cancer cell line shows...Ch. 9 - What characteristics make yeasts a good model for...Ch. 9 - Why is signaling in multicellular organisms more...Ch. 9 - Pseudomonas infections are very common in hospital...
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- What is the mechanism by which R subunits inhibit the C subunits in protein kinase A?arrow_forwardHow does each of these small GTP-binding proteins contribute to the regulation of cell migration?arrow_forwardWhat is the main benefit of cell signaling via direct physical contact and cell signaling over short distances (ex: nerve cell signaling)?arrow_forward
- What is cGMP-dependent protein kinase?arrow_forwardWhat is the effect of having fluctuating cyclin levels throughout the cell cycle, while the levels of its corresponding cyclin dependent kinase stay relatively constant? Explain.arrow_forwardWhy doesn't Cdk1 active immediately upon binding to cyclin B? What other components of the cell’s regulatory machinery could explain the delay in activation of the kinase activity?arrow_forward
- What is the function of Ras during tyrosine kinase cell signaling? a. It activates the opening of channel-linked receptors. b. It is an enzyme that synthesizes second messengers. c. It links the receptor protein to the MAP kinase pathway. d. It phosphorylates other enzymes as part of a pathway.arrow_forwardDoes adenylate cyclase become more active when the inhibitory (Gia) protein is mutated and increases its intrinsic GTPase activity?arrow_forwardCaspases are involved in ______________. Select one: a. promoting the cell cycle b. promoting cell growth c. apoptosis d. tissue regeneration e. DNA synthesisarrow_forward
- What is the benefit of using second messangers and phosphorylation cascades during the transduction step of cell signaling?arrow_forwardIdentify eight general types of protein kinases found in eukaryotic cells, and explain what factor is directly responsible for activating each type.arrow_forwardWhat is the purpose of A kinase–associated proteins (AKAPs)? Describe how AKAPs work in heart muscle cells.arrow_forward
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