BIOCHEMISTRY
9th Edition
ISBN: 2818440090622
Author: BERG
Publisher: MAC HIGHER
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Question
Chapter 9, Problem 8P
Interpretation Introduction
Interpretation:
An explanation corresponding to the fact that the high concentration metal chelator EDTA treatment of carbonic anhydrase results in the loss of activity is to be stated.
Concept introduction:
The biological catalysts which lower the minimum amount of energy required by the reactants to convert into product are known as enzymes. An enzyme does not alter the potential energy of reactant and product. Carbonic anhydrase is an enzyme that is used as a catalytic for the interconversion between
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Instructions.
Given each set of information which may include common name(s) and the reaction catalyzed, you are required to identify the main class of the specific enzyme described.
Name: citryl-CoA synthetase
Reaction: ATP + citrate + CoA = ADP + phosphate + (3S)-citryl-CoA
Name: D-xylulose reductase
Reaction: xylitol + NAD+ = D-xylulose + NADH + H+
Name: cellobiose phosphorylase
Reaction: cellobiose phosphate = α-D-glucose 1-phosphate + D-glucose
Name: carbonic anhydrase
Reaction: H2CO3 = CO2 + H2O
Other info: The enzyme catalyzes the reversible hydration of gaseous CO2 to carbonic acid, which dissociates to give hydrogencarbonate above neutral pH.
Name: pantoate activating enzyme
Reaction: ATP + (R)-pantoate = AMP + diphosphate + (R)-pantothenate.
G. ENZYME CLASSIFICATION.
Identify the main class of enzymes used to catalyzed the following reactions:
1. Lactate dehydrogenase:
NADH+H
NAD
HC-OH
CH3
CH
Pynnte
Lactate
2. Methylmalonyl-CoA mutase:
CH CH
SCOA
CH,CH,
SCOA
coenzyme B12
COO
COO
methylmalonyl-CoA
succinyl-CoA
3. Enolase:
0.
H–Ċ–0–P–0-
C-0–P-0- + H,0
HO–CH,
CH 6
Phosphoenolpyruvate
2-Phosphoglycerate
4. Chymotrypsin:
-0–CH,CH3 + H2O
- RCOOH + HOCH,CH3
5. Pyruvate carboxylase:
coo
• co, • ATP + H,0
H-C-H . ADP + P, + 2H
čoo
CH,
Pyruvate
Oxaleacetate
Paraphrasing Tool .
medicinal meet
Mniversity of Nizwa
pKa of flurazepam is 8.71. Ifthe pH of the stomach is 3.5 and that of intestine is 6.0 then
oral flurazepam will be
t of
Flurazepam
Select one:
a. ionized in the stomach and neutral in the intestine
O b. neutral in the stomach and ionized in the intestine
O c. ionized in both the stomach and the intestine
O d. neutral in both the stomach and the intestine
Which of the following molecules is neutral?
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