Organic Chemistry As a Second Language: Second Semester Topics
Organic Chemistry As a Second Language: Second Semester Topics
4th Edition
ISBN: 9781119110651
Author: David R. Klein
Publisher: WILEY
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Chapter 9.3, Problem 9.19P
Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be suggested.

Organic Chemistry As a Second Language: Second Semester Topics, Chapter 9.3, Problem 9.19P , additional homework tip  1

Concept Introduction:

Ketone or aldehyde can be easily produced by simple chemical reaction.  Therefore, reductive amination results in the formation of amine from ketone or aldehyde.  This can be shown as given below,

Organic Chemistry As a Second Language: Second Semester Topics, Chapter 9.3, Problem 9.19P , additional homework tip  2

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Propose syntheses for the product shown on the left starting from the indicated compound (shown on the right). Your answer should include a retrosynthetic analysis and a proposed synthetic route with reagents.
Propose an efficient synthesis for the following transformation. Hint: For the first problem you will need to use the ozonolysis reaction.
Provide an efficient synthesis for each of the following transformations. Include your retrosynthetic analysis, showing products for each step of the reaction sequence. You are not required to write a mechanism for any of these.

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