Efficient synthesis for the given transformation has to be proposed. Concept Introduction: Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

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Answer 1

Question

Chapter 9.4, Problem 9.25P

Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be proposed.

Concept Introduction:

Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

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Answer 2

Question

Chapter 9.4, Problem 9.25P

Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be proposed.

Concept Introduction:

Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

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Answer 3

Question

Chapter 9.4, Problem 9.25P

Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be proposed.

Concept Introduction:

Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

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Answer 4

Question

Chapter 9.4, Problem 9.25P

Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be proposed.

Concept Introduction:

Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

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Answer 5

Chapter 9.4, Problem 9.25P

Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be proposed.

Concept Introduction:

Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

Answer 6

Chapter 9.4, Problem 9.25P

Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be proposed.

Concept Introduction:

Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

Answer 7

Chapter 9.4, Problem 9.25P

Interpretation Introduction

Interpretation:

Efficient synthesis for the given transformation has to be proposed.

Concept Introduction:

Amino group is a very active group. It is a strong activator when present on the aromatic ring. In order to reduce the activation, the amino group is acylated using any acid chloride. Acylated amino group is a moderate activator. When the amino group is acylated, the para position undergoes reaction without any other side reactions. Once when the required group is installed in the para position, the acyl group is removed from the amine by treatment with acid.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 9.2 - Identify how you would use a Gabriel synthesis to...Ch. 9.2 - Identify how you would use a Gabriel synthesis to...Ch. 9.2 - Identify how you would use a Gabriel synthesis to...Ch. 9.2 - Identify how you would use a Gabriel synthesis to...Ch. 9.2 - Identify whether each of the following compounds...Ch. 9.2 - Identify whether each of the following compounds...Ch. 9.2 - Identify whether each of the following compounds...Ch. 9.2 - Identify whether each of the following compounds...Ch. 9.3 - Suggest an efficient synthesis for each of the...Ch. 9.3 - Suggest an efficient synthesis for each of the...

Solution Summary: The author explains that the amino group is acylated using acid chloride to reduce the activity of amine group. Acyl group can be removed by treatment with acid.

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