elow is a depiction of a replication bubble. 5' AGCTCCGATCGCGTAACTTT 3' TCGAGGCTAGCGCATTGAAA CTAAAGCTTCGGGCATTATCG 3' GATTTCGAAGCCCGTAATAGC CTATCGAGO Consider the following primer which binds to the DNA replication bubble on the diagram above: 5'-GCUAUCG-3'

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 18QP: Replication involves a period of time during which DNA is particularly susceptible to the...
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Below is a depiction of a replication bubble.
5' AGCTCCGATCGCGTAACTTT
3'
TCGAGGCTAGCGCATTGAAA
CTAAAGCTTCGGGCATTATCG 3'
GATTTCGAAGCCCGTAATAGC
TATCGACS
Consider the following primer which binds to the DNA replication bubble on the diagram above:
5'-GCUAUCG-3'
Identify the DNA sequence to which this primer would bind and the orientation.
If the replication fork moves to the right, will the primer be used to create the leading strand of replication
or the lagging strand? Explain your answer
b. If the replication fork moves to the left, will the primer be used to create the leading strand of replication or
a.
the lagging strand? Explain your answer.
What would the next five nucleotides added to the primer by DNA polymerase?
С.
Transcribed Image Text:Below is a depiction of a replication bubble. 5' AGCTCCGATCGCGTAACTTT 3' TCGAGGCTAGCGCATTGAAA CTAAAGCTTCGGGCATTATCG 3' GATTTCGAAGCCCGTAATAGC TATCGACS Consider the following primer which binds to the DNA replication bubble on the diagram above: 5'-GCUAUCG-3' Identify the DNA sequence to which this primer would bind and the orientation. If the replication fork moves to the right, will the primer be used to create the leading strand of replication or the lagging strand? Explain your answer b. If the replication fork moves to the left, will the primer be used to create the leading strand of replication or a. the lagging strand? Explain your answer. What would the next five nucleotides added to the primer by DNA polymerase? С.
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