Given the structures of ddATP and DATP: NH2 NH2 N. HO-P- OH OH OH OH OH OH ddATP DATP A) What would be the effect of adding ddATP (5'-dideoxyadenosine triphosphate) to a DNA replication reaction with DTTP, DCTP, and dGTP instead of DATP (5'-deoxyadenosine triphosphate)? B) What if 33% of the adenosine triphosphate added was ddATP (and the other 67% was DATP)?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
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Given the structures of ddATP and dATP:
NH2
NH2
Ho-fofofa
N.
но
OH
ÓH
OH
ÓH
OH
ddATP
DATP
A) What would be the effect of adding ddATP (5'-dideoxyadenosine triphosphate) to a DNA replication reaction
with DTTP, DCTP, and dGTP instead of DATP (5'-deoxyadenosine triphosphate)?
B) What if 33% of the adenosine triphosphate added was ddATP (and the other 67% was DATP)?
Transcribed Image Text:Given the structures of ddATP and dATP: NH2 NH2 Ho-fofofa N. но OH ÓH OH ÓH OH ddATP DATP A) What would be the effect of adding ddATP (5'-dideoxyadenosine triphosphate) to a DNA replication reaction with DTTP, DCTP, and dGTP instead of DATP (5'-deoxyadenosine triphosphate)? B) What if 33% of the adenosine triphosphate added was ddATP (and the other 67% was DATP)?
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