Following the analysis of a pedigree, a genetic link at 4cM is considered between a mutation leading to a pathology and the molecular marker HUMTH01. The study counts 14 "parental" and 3 "recombinant" individuals. We call p(theta=0.04) is the probability of obtaining such a pedigree in case of a 4cM genetic linkage, p(theta=0.5) is the probability of obtaining such a pedigree in case of independence between the mutation and the marker, Z(theta=0.04) the value of the Lod-score under the assumption of 4cM genetic linkage. Tick all the correct answers: Op(theta=0,04)=1,79.10E-9 and Z(theta=0,04)=0,47 Op(theta=0,5)=7,18.10E-12 p(theta=0,04)=2,75.10E-10 and Z(theta=0,04)=0,77 and Z(theta=0,04)=0,67 and Z(theta=0,04)=0,47 Op(theta=0,5)=6,04.10E-10 Op(theta=0,5) = 9,36.10E-12 and Z(theta=0,04)=1,33 Op(theta =0,5)=5,82.10E-11 and Z(theta=0,04)=0,67 no correct answer Op(theta=0,04)=4,31.10E-11 Op(theta=0,04)=2,01.10E-10 and Z(theta=0,04)=0,77 and Z(theta=0,04)=1,33

Following the analysis of a pedigree, a genetic link at 4cM is considered between a mutation leading to a pathology and the molecular marker HUMTH01. The study counts 14 "parental" and 3 "recombinant" individuals. We call p(theta=0.04) is the probability of obtaining such a pedigree in case of a 4cM genetic linkage, p(theta=0.5) is the probability of obtaining such a pedigree in case of independence between the mutation and the marker, Z(theta=0.04) the value of the Lod-score under the assumption of 4cM genetic linkage. Tick all the correct answers: Op(theta=0,04)=1,79.10E-9 and Z(theta=0,04)=0,47 Op(theta=0,5)=7,18.10E-12 p(theta=0,04)=2,75.10E-10 and Z(theta=0,04)=0,77 and Z(theta=0,04)=0,67 and Z(theta=0,04)=0,47 Op(theta=0,5)=6,04.10E-10 Op(theta=0,5) = 9,36.10E-12 and Z(theta=0,04)=1,33 Op(theta =0,5)=5,82.10E-11 and Z(theta=0,04)=0,67 no correct answer Op(theta=0,04)=4,31.10E-11 Op(theta=0,04)=2,01.10E-10 and Z(theta=0,04)=0,77 and Z(theta=0,04)=1,33

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Description: Following the analysis of a pedigree, a genetic link at 4cM is considered between a mutation leading to a pathology and the molecular marker HUMTH01. Thestudy counts 14 "parental" and 3 "recombinant" individuals. We call p(theta=0.04) is the probabi

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter15: Genomes And Genomics

Section: Chapter Questions

Problem 2QP: Hemophilia and color blindness are both recessive conditions caused by genes on the X chromosome. To...

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