In E. coli, three structural genes (A, D, and E) encode enzymes A, D, and E, respectively. Sequence O is an operator. The sequences are in the order O- A- D- E on the chromosome. The three enzymes encoded by A, D, and E catalyze the biosynthesis of valine. Mutations at the A, D, E, and O were isolated to study the production of enzymes A, D, and E when cellular levels of valine were low (T. Ramakrishnan and E. A. Adelberg. 1965. Journal of Bacteriology 89:654-660). Amounts of the enzymes produced by partial-diploid E. coli with various combinations of mutations are shown in the following table. Amount of enz produced Genotype E D E* D* A* O*/E* D* 1. 2,40 2.00 A* O* E* D* A* O"/E* D* 2. 35.80 38.60 A* O* E* D A* O I 3. E* D* A" O* 1.80 1.00 E* D* A O / 4. 35.30 38.00 E* D A* O* E D* A* O / 5. 2.38 38.00 E* D A* O*

In E. coli, three structural genes (A, D, and E) encode enzymes A, D, and E, respectively. Sequence O is an operator. The sequences are in the order O- A- D- E on the chromosome. The three enzymes encoded by A, D, and E catalyze the biosynthesis of valine. Mutations at the A, D, E, and O were isolated to study the production of enzymes A, D, and E when cellular levels of valine were low (T. Ramakrishnan and E. A. Adelberg. 1965. Journal of Bacteriology 89:654-660). Amounts of the enzymes produced by partial-diploid E. coli with various combinations of mutations are shown in the following table. Amount of enz produced Genotype E D E* D* A* O/E D* 1. 2,40 2.00 A* O* E* D* A* O"/E* D* 2. 35.80 38.60 A* O* E* D A* O I 3. E* D* A" O* 1.80 1.00 E* D* A O / 4. 35.30 38.00 E* D A* O* E D* A* O / 5. 2.38 38.00 E* D A* O*

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter15: From Dna To Protein

Section15.1: The Connection Between Dna, Rna, And Protein

Problem 1SB

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