Mach the terms left with as many terms GMP Nucleotide at right by entering @ Nucleoside 3 Z-DNA Subunit of chromatin
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- Which of the following is associated with active chromatin? Check all that apply. A. Centromeres B. heterochromatin C. histone acetylation D. Polytene puffs E. metaphase chromasomes F. transcription of machineryFigure 28.11 depicts the eukaryotic cell cycle. Many cell types “exit� the cell cycle and don’t divide for prolonged periods, a state termedG0; some, for example neurons, never divide again. a. In what stage of the cell cycle do you suppose a cell might be when it exits the cell cycle and enters G0? b. The cell cycle is controlled by checkpoints, cyclins, and CDKs. Describe how biochemical events involving cyclins and CDKs might control passage of a dividing cell through the cell cycle.Need help If the mitotic spindle does not correctly attach to chromosome kinetochores, the spindle assembly checkpoint will be activated. Select all correct outcomes for chromosomes not correctly attached to mitotic spindle A) centrosome duplication will not occur B) M cyclin will be degraded C) APC will be inhibited D) chromosomes will not segregate E) Mad2 will bind to unattached kinetochores F) mitosis will halt at metaphase/anaphase transition
- Which of the following is not a major class of chromatin proteins?a) Histonesb) Topoisomerasesc) SMC proteinsd) Cohesins2. Give at least one example of a chromosomal structureor function affected by the following mechanisms formodulating chromatin structure:a. Posttranslational changes of the normal histonesfound in the nucleosomeb. Nucleosomes with variant histones encoded byspecial genesMatch the process with the correct phase of the cell cycle (G1, S, G2, M). If the process occurs in M phase indicate subphase (ex. telophase). E) ___________________Extra cell membrane is synthesized by the smooth ER. F) ___________________DNA is compacted into chromatin.
- Fill in the blanks Packaging of DNA into 10 nm chromatin fiber shortens it’s length approximately _________ folds. In humans and other primates the primary centromeres sequence is ___________ DNA, which is a __________ base pair sequence arranged in tandem repeats spanning up to millions of base pairs.Fill in the blank: _______________ are structures formed of DNA wrapped around histone proteins that are visible and only seen during cell division (eg. mitosis)6. This is where the RNA polymerase is bound and a short region of DNA is accessible to begin the process of transcription. Group of answer choices 1. Open Chromatin 2. Open Promoter Complex 3. Closed Promoter Complex 4. Closed Chromatin
- Which region of chromatin is transcriptionally silent?a) Nucleoidb) Centromerec) Euchromatind) HeterochromatinIn mammals, individuals with two X chromosomes usually de-activate one of the X chromosomes inside most of the organism's clls. The de-activated X chromosome is called a Barr body, and almost no transcription occurs from it. You would expect the Barr body to be composed of 1.) euchromatin 2.) RNA 3.) heterochromatin 4.) single-stranded DNAWhich of the following statements most accurately represent chromatin state and transcription? Group of answer choices 1.Histone deacetylases promote closed chromatin and result in repressed transcription 2.Open chromatin is associated with hypoacetylation and has high levels of transcription 3.Histone acetyltransferases result in hypoacetylation and high levels of transcription 4.Hyperacetylation is associated with closed chromatin and low levels of transcription