The following DNA sequence occurs as the template strand:   3’ – TACGGGGATCAGATTATC – 5’ DNA template   What single nucleotide deletion within the DNA sequence would cause a frame shift and a premature STOP codon? Write down the sequence of the New DNA template after deletion of the single nucleotide and also that of the New mRNA transcript, and specify the 5’ and 3’ ends of both the template and the mRNA transcript. Highlight the premature stop codon in the mRNA transcript.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
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Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 17QP: Given the following mRNA, write the double-stranded DNA segment that served as the template....
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  1. The following DNA sequence occurs as the template strand:

 

3’ – TACGGGGATCAGATTATC – 5’ DNA template

 

What single nucleotide deletion within the DNA sequence would cause a frame shift and a premature STOP codon? Write down the sequence of the New DNA template after deletion of the single nucleotide and also that of the New mRNA transcript, and specify the 5’ and 3’ ends of both the template and the mRNA transcript. Highlight the premature stop codon in the mRNA transcript.

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