EBK GENETICS: FROM GENES TO GENOMES
EBK GENETICS: FROM GENES TO GENOMES
5th Edition
ISBN: 8220100255250
Author: HARTWELL
Publisher: YUZU
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Chapter 1, Problem 12P

A single zebrafish gene function was inactivated completely by mutation, and a zebrafish with this mutation had none of its normal horizontal stripes. For each of the following statements, indicate whether the statement is certainly true, certainly untrue, or if there is insufficient information to decide.

a. The normal gene function is required for the viability of the zebrafish.
b. The normal gene function is required for the formation of stripes.
c. The normal gene function is required to make the pigment deposited in the stripes.
d. The gene is required in zebrafish only for stripe formation.
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A single zebrafish gene function was inactivated completely by mutation, and a zebrafish with this mutation had none of its normal horizontal stripes. Foreach of the following statements, indicate whether the statement is certainly true, certainly untrue, or if thereis insufficient information to decide.a. The normal gene function is required for the viability of the zebrafish.b. The normal gene function is required for the formation of stripes.c. The normal gene function is required to make thepigment deposited in the stripes.d. The gene is required in zebrafish only for stripeformation.
Most organisms display a circadian rhythm, a cycling of biological processes that is roughly synchronized with day length.  In Drosophila, pupae eclose (emerge as adults after metamorphosis) at dawn. a)Using this knowledge how would screen for Drosophila mutants that have an impaired circadian rhythm? b)In each case, how would you clone the genes you identified by mutation?
The functions of almost all of the genes in the lambda genome were first explored using mutations. What do you think the mutant phenotype would be if you made an inactivating mutation in the c gene, and why? Be very specific but also very brief.
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