Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
2nd Edition
ISBN: 9780137533114
Author: Dean Appling, Spencer Anthony-Cahill
Publisher: PEARSON+
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 10, Problem 3P
The classic demonstration that cell plasma membranes are composed of bilayers depends on the following kinds of data:
- The membrane lipids from 4.74 ×109 erythrocytes will form a monolayer of area 0.89 m2 when spread on water surface. The surface of one erythrocytes is approximately 100
- m2 in area. Show that these data can be accounted for only if the erythrocyte membrane is a bilayer.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
The classic demonstration that cell plasma membranes are composed ofbilayers depends on the following kinds of data:• The membrane lipids from 4.74 x 109 erythrocytes will form a monolayerof area 0.89 m2 when spread on a water surface.• The surface of one erythrocyte is approximately 100 μm2 in area.Show that these data can be accounted for only if the erythrocyte membraneis a bilayer.
. The classic demonstration that cell plasma membranes are composed of
bilayers depends on the following kinds of data:
• The membrane lipids from 4.74 X 1o° erythrocytes will form a mono-
layer of area 0.89 m² when spread on a water surface.
• The surface of one erythrocyte is approximately 100 um in area.
Show that these data can be accounted for only if the erythrocyte membrane
is a bilayer.
A solution containing 3.58 x 1023 molecules/m3 of protein in water is separated from pure water by a membrane 3.20 μm thick. The diffusion coefficient of the protein through the membrane is 7.15 x 10-18 m2/s. On average, how many molecules cross 0.0240 μm2 of this membrane each second? [Answer as a positive number with 3 sig digits, but do not enter units with your answer]
Chapter 10 Solutions
Pearson eText for Biochemistry: Concepts and Connections -- Instant Access (Pearson+)
Ch. 10 - Prob. 1PCh. 10 - Given these molecular components--glycerol, fatty...Ch. 10 - The classic demonstration that cell plasma...Ch. 10 - The lipid portion of a typical bilayers is about...Ch. 10 - In the following situations, what is the free...Ch. 10 - Propose an experiment that would distinguish...Ch. 10 - Prob. 7PCh. 10 - Peptide hormones (such as insulin) must bind to...Ch. 10 - Prob. 9PCh. 10 - Prob. 10P
Ch. 10 - Prob. 11PCh. 10 - Prob. 12PCh. 10 - Prob. 13PCh. 10 - Prob. 14PCh. 10 - The concentration of glucose in your circulatory...Ch. 10 - ATP is synthesized from ADP, Pi , and a proton on...Ch. 10 - The Na+/ glucose symport transports glucose from...Ch. 10 - Prob. 18PCh. 10 - Prob. 19PCh. 10 - The transport of aspirin (pKa = 3.5, structure...Ch. 10 - Prob. 21P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Many biological tissues have layers with extracellular matrix components and different orientations of these components. As a result, diffusion coefficients vary from region to region. Consider the steady-state, one-dimensional diffusion of a protein across a tissue that consists of a cellular phase and an acellular phase (like an artery wall consisting of a layer of smooth muscle cells and a layer of elastic lamina. Assume no reactions occur in either layer. The protein diffusion coefficients in the layers (1 and 2) are Di,1 and Di,2. The concentration at one edge is (x = 0) Ci = C0; on the other edge (x = L1 + L2 = L) Ci = CL. Assume that all partition coefficients in both layers are equal to 1. Use the figure below to help. Determine (A)the concentration as a function of position x, (B) the flux of the protein solute across the tissue, and (C) the effective diffusion coefficient if the system is modeled as a single layer.arrow_forwardThe inner leaflet (monolayer) of the human erythrocyte membrane consists predominantly of phosphatidylethanolamine and phosphatidylserine. The outer leaflet consists predominantly of phosphatidylcholine and sphingomyelin. Although the phospholipid components of the membrane can diffuse in the fluid bilayer, this sidedness is preserved at all times. How?arrow_forwardA new protein namely protein X has been isolated by molecular biologists. The protein is shown to have a spherical shape and a radius of 12 nm. Before they could measure its diffusion coefficient at 25°C, their device breaks. However, they have data from a previous measurement taken using the same device, at 25°C which showed diffusion coefficient of albumin (spherical with R=3 nm, M= 68,000 g/mol) to be 6.8x10-7 cm2/s. Determine the diffusion coefficient of protein X.arrow_forward
- Phospholipid lateral motion in membranes is characterized by a diffusion coefficient of about 1 x 10-8 cm2/sec. The distance traveled in the membrane in a given time is r = √4Dt, where r is the distance traveled in centimeters is the diffusion coefficient, and t is the time during which diffusion occurs. Calculate the distance (in nanometers) traveled by a phospholipid in a bilayer in 25 msec (milliseconds).arrow_forwardIf you made a hematocrit in two tubes. Tube A is made of 0.60M NaCl, and Tube B is made of 1.00M of NaCl, describe how the cell would respond in these solutions? Which would have a higher rate of osmosis? If the cell is permeable to NaCl, which would have a higher rate of diffusion?arrow_forwardYou are developing a porous membrane for use in a dialysis system. The membrane must be able to retain both protein and glucose on the inlet side and allow other, smaller molecules to flow through. You have found that the membrane is 0.25 mm thick and contains long, rectangular pores with a width of 0.1 microns. 57% of the 50 cm^2 membrane surface area is covered with pores. A test fluid (viscosity = 1.5 cP, density = 1015 kg/m^3) is passed through the membrane. You can assume that the test fluid has a composition similar to that of blood plasma. An initial test is run at physiological conditions, and you observe that the flow rate of fluid through the membrane is 500 cm^3/min. _Given this data, what must the hydrodynamic pressure drop across the membrane in your test system be in pascals?arrow_forward
- A researcher is isolating proteins from a cell via different techniques. They find that when the cell is ground with a blender, all of the proteins in the cell can be extracted. However if instead the cell membranes are agitated in a 1.2 M KCl mixture, only about 70% of the total protein is extracted.What class of membrane proteins are in this soluble extract and what forces normally hold them to the membrane?What class of membrane proteins are the 30% of proteins that remain behind, and what forces hold these proteins in the membrane? If a solution of ionic solids was not available, what other solvent systems could be used to extract these proteins?arrow_forwardShown below are cells (colored) that were recently placed into a beaker containing a clear solution For each scenario, indicate whether movement of the molecule into the cell will occur using facilitated diffusion or active transport. А. B. 125mM 20mM fructose glucose 85MM 35mM fructose glucose OA= facilitated diffusion; B= facilitated diffusion OA= active transport; B= active transport O A= active transport; B= facilitated diffusion A= facilitated diffusion; B= active transportarrow_forwardUncharged molecules can passively pass through membranes more readily than charged molecules. Acetylsalicylic acid, better known as aspirin, has a single carboxylate group with a pKa of 3.5. Approximately what percentage of the molecule is charged in the stomach, and approximately what percentage is charged at normal blood pH at the surface of a blood vessel? Finally, per unit surface area, where would the rate of passive transfer across a membrane be highest? A.) 1%, >99%, stomach B.) >99%, 1%, stomach C.) 1%, >99%, blood vessel D.) 50%, 50%, blood vessel E.)>99%, 1%, blood vessel F.) 50%, 50%, stomacharrow_forward
- The mixing of liquids is critical in microfluidic analytical systems and is often taking place in Y-shaped junctions as seen in Figure Q4b. The inlets are 50 μm wide and 50 µm high, and the outlet is 50 μm wide and 50 μm high. The aim of the device is to analyse IgG with a diffusion coefficient of 4-10 cm²-s¹. Determine the shortest length of the channel to ensure complete mixing when the flowrate in each of the inlet channels is 1 µl/h. [4] Inlet 1 50 µm Inlet 2 Select one: O a. 8.65mm O b. 3.47 mm O c. 112 pm O d. 5.34 mm 50 µm Outlet Figure Q4b. Schematic of a Y-shaped microfluidic device used for mixing two fluids.arrow_forwardIt is typically sufficient to rupture cells when the solute concentration is reduced from 0.15M to 0.001M. Calculate what transmembrane pressure this would result in. Use that to access if the red blood cells would break. Yes or No? Compare to the transmembrane pressure when cells are in normal saline solution (0.91%NaCl) -> 0.156M(change unit to osM) Basically Calculate the transmembrane pressure when the solute concentration is reduced from 0.15M to 0.001M Determine if that transmembrane pressure would result in the breakage of red blood cells Calculate the transmembrane pressure when cells are in a normal saline solution and comparearrow_forwardA large chaperone protein complex GroEL is approximately 16 nm in diameter. When it is dissolved in water at 300 K, estimate the average time it will take for GroEL to diffuse a distance of 500 nm (0.5 micron). The viscosity of water is 10-3 Pa*s.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
- BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningFundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license