Essentials of Genetics - Masteringgenetic
9th Edition
ISBN: 9780134143699
Author: KLUG
Publisher: PEARSON
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Chapter 11, Problem 19PDQ
Summary Introduction
To review:
The distribution of nucleosome on the newly synthesized chromatin.
Introduction:
Chromatin is a complex of DNA (deoxyribonucleic acid) and proteins in the eukaryotic cells that forms the chromosome. The packaging of the chromatin thread into the chromosome is done by a nucleosome. The nucleosome is the basic unit of packaging consisting of DNA molecules wrapped around the histone proteins to form a condensed structure of the genome.
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A circular molecule of DNA contains 1 million base pairs. If the rate of DNA synthesis at a replication fork is 100,000 nucleotides per minute, how much time will theta replication require to completely replicate the molecule, assuming that theta replication is bidirectional? How long will replication of this circular chromosome by rolling-circle replication take? Ignore replication of the displaced strand in rolling-circle replication.
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Chapter 11 Solutions
Essentials of Genetics - Masteringgenetic
Ch. 11 - CASE STUDY | Art inspires learning A genetics...Ch. 11 - Prob. 2CSCh. 11 - Prob. 3CSCh. 11 -
HOW DO WE KNOW?
1. In this chapter, we focused on...Ch. 11 - Review the Chapter Concepts list on p. 199. These...Ch. 11 - Prob. 3PDQCh. 11 - Describe how giant polytene chromosomes are...Ch. 11 - What genetic process is occurring in a puff of a...Ch. 11 - Prob. 6PDQCh. 11 - Why might we predict that the organization of...
Ch. 11 -
8. Describe the sequence of research findings...Ch. 11 - Prob. 9PDQCh. 11 - Prob. 10PDQCh. 11 - Provide a comprehensive definition of...Ch. 11 - Prob. 12PDQCh. 11 - Define satellite DNA. Describe where it is found...Ch. 11 - Prob. 14PDQCh. 11 -
15. Mammals contain a diploid genome consisting...Ch. 11 - Prob. 16PDQCh. 11 - Prob. 17PDQCh. 11 - Prob. 18PDQCh. 11 - Prob. 19PDQCh. 11 - The human genome contains approximately 106 copies...Ch. 11 - Prob. 21PDQ
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- Most prokaryotes have a circular chromosome, with no ends, so the shortening of DNA does not occur. But what protects the genes of linear eukaryotic chromosomes from being eroded away during successive rounds of DNA replication?arrow_forwardDeamination of adenine results in the formation of hypoxanthine. Hypoxanthine selectively base pairs with cytosine. If this error is not corrected, what base pair can the original A·T base pair be converted to after cycles of DNA replication?a) G·C b) C·G c) T·A d) A·Garrow_forwardThe telomeres of a linear chromosome are made of identical directly repeated DNA sequences. How does the enzyme telomerase generate these DNA repeats?arrow_forward
- With regard to DNA replication, define the term bidirectional replication.arrow_forwardIn one, simple sentence define the function of the following 1. Helicase = 2. Alpha subunit of DNA polymerase III =arrow_forwardWhat similarities and differences exist in the enzymatic activities of DNA polymerases I and III? What is the function of each DNA polymerase in bacterial cells?arrow_forward
- What observations reveal that a “telomere problem” exists during eukaryotic DNA replication, and how did we learn of the solution to this problem?arrow_forwardWhat is one enzyme that is involved with DNA replication and how would the absence of this enzyme affect replication of both prokaryotic and eukaryotic DNA?arrow_forwardSuppose that 28% of the nucleotides in a DNA moleculeare deoxythymidine 5′- monophosphate, and that duringDNA replication the percentage amounts of availablenucleotide bases are 22% A, 22% C, 28% G, and 28% T.Which base would be depleted first in the replicationprocess?arrow_forward
- Considering prokaryotes, what term adds nucleotides in the 5' to 3' direction during DNA replication?arrow_forwardHow important and useful to the cell is the ability of the DNA to assume various forms? Why are these various forms necessary?arrow_forwardHuman Fbh1 helicase is important in the process of DNA replication. When a mutation occurs during the production of Fbh1, the result is a mutant Fbh1 that binds at the replication fork and prevents any helicase protein from attaching to the strand. Based on this information and the image shown, what would happen during DNA replication if this mutant helicase were present? A - Topoisomerase would unwind the DNA and an RNA primer would attach to the DNA molecule and initiate replication. The process would then stop at the blue triangle because helicase is needed to separate the strands of DNA. B - Topoisomerase would unwind the DNA, but then the process would stop at the blue triangle because helicase, the RNA primer, would not be able to attach to the DNA molecule and initiate replication. C - The process would begin at the blue triangle when topoisomerase unwinds the DNA and an RNA primer attaches to the DNA molecule and initiates replication. DNA polymerase would begin the synthesis…arrow_forward
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