Concept explainers
Coated Vesicles in Intracellular Transport. For each of the following statements, indicate for which coated vesicle the statement is true: clathrin- (C), COPI- (I), or COPII-coated (II). Each statement may be true for one, several, or none (N) of the coated vesicles discussed in this chapter.
(a) Binding of the coat protein to an LDL receptor is mediated by an adaptor protein complex.
(b) Fusion of the vesicle (after dissociation of the coat) with the Golgi membrane is facilitated by specific t-SNARE and Rab proteins.
(c) Has a role in bidirectional transport between the ER and Golgi apparatus
(d) Has a role in sorting proteins for intracellular transport to specific destinations
(e) Has a role in transport of acid hydrolases to late endosomes
(f) Is essential for all endocytic processes
(g) Is important for retrograde traffic through the Golgi apparatus
(h) Is involved in the movement of membrane lipids from the TGN to the plasma membrane
(i) The basic structural component of the coat is called a triskelion.
(j) The protein coat dissociates shortly after formation of the vesicle.
(k) The protein coat always includes a specific small GTP-binding protein.
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Becker's World of the Cell (9th Edition)
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