Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 12, Problem 12.9PS

Sorting Proteins. Specific structural features tag proteins for transport to various intracellular and extracellular destinations. Several examples were described in this chapter, including (1) the short peptide Lys-Asp-Glu-Leu, (2) characteristic hydrophobic membrane-spanning domains, and (3) mannose-6-phosphate residues attached to oligosaccharide side chains. For each structural feature, answer the following questions:

(a) Where in the cell is the tag incorporated into the protein?

(b) How does the tag ensure that the protein reaches its destination?

(c) Where would the protein likely go if you were to remove the tag?

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