EBK GENETICS: FROM GENES TO GENOMES
6th Edition
ISBN: 9781260041255
Author: HARTWELL
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 12, Problem 29P
Summary Introduction
To determine:
The effect of expressing shugoshin had on the mitotically dividing cells expressing Rec8 and the
Introduction:
Shugoshin N-terminal coiled-coil region is a domain found in the N-terminal of the Shugoshin protein in the eukaryotes. The major role of shugoshin protein is to regulate the chromosome cohesion during cell division.
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During metaphase I of meiosis, tetrads align along the metaphase plate independently of each other. Therefore, there is a random “shuffle” of maternal and paternal chromosomes in the resulting gametes.The following diagram demonstrates how this works in a diploid cell with four chromosomes (2n=4) . Because there are two pairs of chromosomes and each pair can align in one of two ways during metaphase I, the number of possible variations in the gametes produced is 22 or 4.For an organism that is , there are three pairs of chromosomes, so the number of possible variations in the gametes produced due to independent assortment in metaphase I is 23 or 8.
In an organism with a haploid number of 7, how many possible combinations of maternal and paternal chromosomes can occur in its gametes?
a. 72=49
b. 27=128
c.17=1
d. 214=16 384
A cell undergoing division has a haploid chromosome number of 15. Give the numerical value for each of the following:
1. number of chromatids in a cell in metaphase of meiosis II2. number of centromeres in a cell in prophase of meiosis II
3. number of centromeres following cytokinesis of meiosis I
A diploid cell has 15 picograms of DNA in G₁ phase. If this cell is a germ line cell that undergoes meiosis, how much DNA will each daughter cell contain at the end of
meiosis I? How much DNA will each daughter cell contain at the end of meiosis II?
MI = 30 pg: MII = 15 pg
O MI = 15 pg; MII = 15 pg
MI = 7.5 pg; MII = 15 pg
O MI = 15 pg: MII = 7.5 pg
Chapter 12 Solutions
EBK GENETICS: FROM GENES TO GENOMES
Ch. 12 - For each of the terms in the left column, choose...Ch. 12 - Many proteins other than histones are found...Ch. 12 - What difference exists between the compaction of...Ch. 12 - What is the role of the core histones in...Ch. 12 - a. About how many molecules of histone H2A would...Ch. 12 - The enzyme micrococcal nuclease can cleave...Ch. 12 - a. What letters are used to represent the short...Ch. 12 - About 2000 G bands are visible in a...Ch. 12 - Suppose you performed a fluorescence in situ...Ch. 12 - Which of the following would be suggested by a...
Ch. 12 - For each of the following pairs of chromatin...Ch. 12 - a. Drosophila b. Humans Give examples of...Ch. 12 - One histone modification that is seen consistently...Ch. 12 - Recently, scientists constructed a transgene that...Ch. 12 - Drosophila geneticists have isolated many...Ch. 12 - On the following figures, genes A and B are on the...Ch. 12 - Prob. 17PCh. 12 - The first page of this chapter displays photos of...Ch. 12 - The human genome contains about 3 billion base...Ch. 12 - The mitotic cell divisions in the early embryo of...Ch. 12 - In an experiment published in the journal Cell in...Ch. 12 - a. What DNA sequences are found at the telomeres...Ch. 12 - Prob. 23PCh. 12 - a. In a fluorescent in situ hybridization FISH...Ch. 12 - If you are comparing the two telomeres in each...Ch. 12 - a. What DNA sequences are commonly found at human...Ch. 12 - On the graphs presented in Problem 21, no data is...Ch. 12 - Prob. 29PCh. 12 - Prob. 30PCh. 12 - In the 1920s, Barbara McClintock, later a Nobel...Ch. 12 - Give at least one example of a chromosomal...Ch. 12 - Cornelia de Lange syndrome CdLS is a rare human...Ch. 12 - a. Give at least three examples of types of...Ch. 12 - A number of yeast-derived elements were added to...Ch. 12 - Prob. 36PCh. 12 - The completely synthetic yeast chromosome Syn III...
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- Variations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it takes place during cell division.arrow_forwardIn the following diagram, designate each daughter cell as diploid (2n) or haploid (n).arrow_forwardMeiosis is characterized by the pairing of homologouschromosomes during prophase I. In many species, an elaboratestructure called the synaptonemal complex forms betweenhomologues. During this pairing, homologues may exchangechromosomal material at sites called chiasmata. In meiosis I, thehomologues separate from each other, reducing the chromosomenumber to the haploid state (thus the reductive division). It isfollowed by a second division without replication, during whichsister chromatids become separated. The result of meiosis I and IIis four haploid cells. If sister chromatids separated at the first division, would meiosis still work?arrow_forward
- It is possible that an alternative mechanism for generating germ cells could have evolved. Consider meiosis in a germ cell precursor (a cell that is diploid but will go on to make gametes). If the S phase were skipped, which meiotic division (meiosis I or meiosis II) would no longer be required? Explain.arrow_forwardTruffles (Tuber borchi) have 2n=8 chromosomes. For the mitotic and meiotic stages below, draw the chromosomes and chromatids, and give the number of homologous pairs, chromosomes, and chromatids present. Be sure to differentiate homologous chromosomes by using size, shape, or other labeling mechanism. Metaphase of mitosis ( # homologous pairs # chromosomes # chromatids Anaphase of meiosis II – draw and count chromosomes for only 1 cell ( # homologous pairs # chromosomes # chromatidsarrow_forwardA certain species of animal has 18 chromosomes in its diploid cells (2n=18). Describe what the metaphase chromosome arrangement would look like for this species in each of the following stages: mitosis, meiosis I, and meiosis IIarrow_forward
- Mutations in genes that affect meiosis have been identified in many different model organisms. Most of these mutations result in aneuploidy of more than a single chromosome and are nearly sterile. Explain why this is the case.arrow_forwardA chromosome that was involved in a reciprocal translocation alsohas an inversion. In addition, the cell contains two normalchromosomes.Make a drawing that shows how these chromosomes will pair duringmetaphase of meiosis I.arrow_forwardMeiosis is also known as reduction cell division because it reduces the ploidy level from diploid (2n) to haploid (n). Why do we need to reduce our ploidy level in certain cells?arrow_forward
- Consider a diploid cell that contains 7 pairs of chromosomes. Each pair includes a maternal and a paternal member (for example: AP pair) or AP B ^ n * B ^ p (two pairs). How many different combinations of chromatids are possible during the early phases of anaphase in meiosis II?arrow_forwardIn kangaroos, the somatic cells are diploid, having 22 chromosomes. How many chromosomes are present in each cell at metaphase II of meiosis?arrow_forwardSuppose the diagram below shows a cell during metaphase Meiosis II: microtubule a) Label the elements of the figure. b) Assuming all of the chromosomes present during Meiosis II are shown in the figure above, how many chromosomes (counting homologous pairs as two chromosomes a cell from this organism have immediately after fertilization? Tne left Showarrow_forward
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