Human Physiology: An Integrated Approach (8th Edition)
8th Edition
ISBN: 9780134605197
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 12, Problem 34RQ
Summary Introduction
To determine: The appropriate hypothesis regarding the cause of muscle fatigue, as shown in the graph given in the book.
Introduction: Muscle fatigue is a medical condition that is characterized by the decrease in the performance of muscles observed after a period of intense physical activity. It depends on various factors. This condition reduces the performance of an individual during exercise and playing sports. It is caused by the failure to generate and maintain power. In the experiment, four metabolites were tested for their role in causing muscle fatigue. The four metabolites were ATP, lactate, phosphocreatine (PCr), and creatine(Cr). The presence of these metabolites was measured before at rest and then after cycling. The results were represented in the form of a graph.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Which of the following is the correct summary of the anaerobic breakdown of glucose in the skeletal muscle?
Glucose + ADP + Pi ⟶ lactate + ATP
Glucose + 2ADP + 2Pi ⟶ 2 lactate + 2ATP
Glucose + 2ADP + 2Pi + 2NAD+ ⟶ 2 pyruvate + 2ATP + 2NADH + 2H+
Glucose + ADP + Pi ⟶ pyruvate + ATP
Glucose + 2ADP + 2Pi ⟶ 2 pyruvate + 2ATP
If you were able to control fatigue in the muscle cell experimentally such that you only exposed the muscle to high levels of Pi and no other metabolites, what would you observe?
A decline in force without much change in velocity
A decline in velocity without much change in force
A muscle operating below Lo
A decline in both force and velocity
An increased affinity of Ca2+ for troponin
Km of muscle hexokinase is _________ than that of liver glucokinase enzyme. As a result, the velocity of the reactions catalyzed by hexokinase is _________ as compared to glucokinase at a physiological concentration of 5mM glucose.
Lower; Low
Higher; low
Lower, High
Higher; High
Chapter 12 Solutions
Human Physiology: An Integrated Approach (8th Edition)
Ch. 12.1 - Identify as many pairs of antagonistic muscle...Ch. 12.1 - Prob. 2CCCh. 12.1 - Prob. 3CCCh. 12.1 - Prob. 4CCCh. 12.1 - What are the three anatomical elements of a...Ch. 12.1 - What is the chemical signal at a neuromuscular...Ch. 12.1 - Prob. 7CCCh. 12.1 - Prob. 8CCCh. 12.1 - Prob. 9CCCh. 12.1 - Name an elastic fiber in the sarcomere that aids...
Ch. 12.1 - Prob. 11CCCh. 12.1 - Prob. 12CCCh. 12.1 - Prob. 13CCCh. 12.1 - According to the convention for naming enzymes,...Ch. 12.1 - Prob. 15CCCh. 12.1 - Prob. 16CCCh. 12.1 - Summation in muscle fibers means that the...Ch. 12.1 - Prob. 18CCCh. 12.1 - Which type of runner would you expect to have more...Ch. 12.1 - What is the response of a muscle fiber to an...Ch. 12.1 - Prob. 21CCCh. 12.2 - One study found that many world-class athletes...Ch. 12.3 - What is the response of a muscle fiber to an...Ch. 12.3 - Prob. 24CCCh. 12.3 - Prob. 25CCCh. 12.3 - Prob. 26CCCh. 12.3 - Prob. 27CCCh. 12.3 - Prob. 28CCCh. 12.3 - What happens to contraction if a smooth muscle is...Ch. 12.3 - Prob. 30CCCh. 12.3 - Prob. 31CCCh. 12.3 - Prob. 32CCCh. 12.3 - How can a neuron alter the amount of...Ch. 12.3 - Prob. 34CCCh. 12.3 - Prob. 35CCCh. 12 - The three types of muscle tissue found in the...Ch. 12 - Which two muscle types are striated?Ch. 12 - Which type of muscle tissue is controlled only by...Ch. 12 - Arrange the following skeletal muscle components...Ch. 12 - The modified endoplasmic reticulum of skeletal...Ch. 12 - Prob. 6RQCh. 12 - Prob. 7RQCh. 12 - List six proteins that make up the myofibrils....Ch. 12 - List the letters used to label the elements of a...Ch. 12 - Briefly explain the functions of titin and...Ch. 12 - During contraction, the __________ band remains a...Ch. 12 - Explain the sliding filament theory of...Ch. 12 - Explain the roles of troponin, tropomyosin, and...Ch. 12 - Which neurotransmitter is released by somatic...Ch. 12 - What is the motor end plate, and what kinds of...Ch. 12 - Prob. 16RQCh. 12 - Prob. 17RQCh. 12 - Prob. 18RQCh. 12 - The basic unit of contraction in an intact...Ch. 12 - The two functional types of smooth muscle are...Ch. 12 - Prob. 21RQCh. 12 - Prob. 22RQCh. 12 - Prob. 23RQCh. 12 - Define muscle fatigue. Summarize factors that...Ch. 12 - Prob. 25RQCh. 12 - Prob. 26RQCh. 12 - Prob. 27RQCh. 12 - What is the role of the sarcoplasmic reticulum in...Ch. 12 - Compare and contrast: a. fast-twitch...Ch. 12 - Prob. 30RQCh. 12 - One way that scientists study muscles is to put...Ch. 12 - Prob. 32RQCh. 12 - On the basis of what you have learned about muscle...Ch. 12 - Prob. 34RQCh. 12 - Prob. 35RQ
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Intracellular concentrations in resting muscle are as follows: fructose6-phosphate, 1.0 mM; fructose-1,6-bisphosphate, 10 mM; AMP, 0.1 mM;ADP, 0.5 mM; ATP, 5 mM; and Pi, 10 mM. Is the phosphofructokinasereaction in muscle more or less exergonic than under standard conditions?By how much?arrow_forwardDescribe the two mechanisms by which muscle glycogen is broken down to glucose (glycogenolysis) for use in glycolysis. Which one is activated at the same time as muscle contraction?arrow_forwardWhich of the following is a valid statement about lactate? a. Is responsible for the burning sensation in the muscles during exercise b. Primarily produced as a result of insufficient oxygen availability in the cell c. Causes DOMS after rigorous exercise d. “Metabolic waste product” produced during exercise e. Ice massage should be employed after exercise to flush lactate out of the skeletal muscle after exercise f. None of the above are true g. Both A and B are truearrow_forward
- I do not know which diagram is for this question but please see and answer this question. I need help Question: Which of the following statements regarding carbohydrate and fat metabolism during exercise is true? A: plasma glucose contributes more to energy provision than does muscle glycogen at 85% Vo2 max B: the utilization of fat as an energy source is greatest at the highest exercise intensities e.g. greater than 85% VO2 max C: carbohydrate supplementation during moderately intense exercise (eg. 70-80% VO2 max) can help one to exercise longer until the onset of fatigue D: the greatest amount of glycogen is used at around 65% VO2 maxarrow_forwardWhich of the following are the effects of insulin on skeletal muscle cells and which are not? Which are the effects of insulin on adipocytes? Inhibits gluconeogenesis Inhibits lipolysis Stimulates glucose entry into cell Stimulates glycogenolysis Stimulates triglyceride synthesisarrow_forwardIn an isometric contraction, the muscle ________." shortens without a load does not change in length but increases tension is not stimulated by a motor neuron is unable form cross-bridges and fails to develop tension Which method of regenerating ATP is used in a very short duration activity, such as a 100m sprint, because it is the most rapid method of regenerating ATP?" aerobic respiration in the mitochondria glycolysis in the mitochondria anaerobic respiration in the cytoplasm (or cytosol) breaking a phosphate bond on phosphocreatine The metabolic pathway that results in the production of two net ATPs per glucose plus two pyruvic acid molecules ________. only occurs within the mitochodria is called glycolysis only occurs when there is no oxygen present is the main method of generating ATP for maximum effort activities that last 1-2 Where does overÊ95% of a skeletal muscle cell's energyÊcome from during both rest andÊmoderate exercise? creatine phosphate lactic acid anaerobic…arrow_forward
- What are the three major mechanisms by which exercise increases glycolytic rate?arrow_forwardDefine a kilocalorie and how might this concept be applied to the field of exercise science? Provide a brief example of how a MET may be converted to a caloric equivalent.arrow_forwardAs the duration of a maximal effort increases from 10 seconds or less to between 10 and 180 seconds, what factor becomes limiting in terms of energy production?arrow_forward
- What would be the ATP yield per molecule of glucose in the muscle if glycogen were the source of the glucose?arrow_forwardThe switch from aerobic to anaerobic respiration characterizes all types of shock. This results in less efficient energy production and an increase in lactic acid. Which of the following contributes to this switch to anaerobic metabolism? Question 1 options: a) Hypoperfusion b) Hypokalemia c) Hyperglycemia d) Hypertensionarrow_forwardAn athlete is aiming to optimize their protein intake for muscle repair and growth. Which of the following dietary modifications could potentially enhance the utilization of dietary protein for muscle protein synthesis?A) Consuming protein exclusively from plant-based sources like lentils and beans.B) Spreading protein intake evenly throughout the day, including after exercise.C) Increasing protein intake to more than 3 grams per kilogram of body weight daily.D) Exclusively consuming protein shakes immediately post-workout.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Nutritional Sciences: From Fundamentals to Food, ...Health & NutritionISBN:9781337486415Author:McGuirePublisher:CengageLifetime Physical Fitness & WellnessHealth & NutritionISBN:9781337677509Author:HOEGERPublisher:Cengage
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Nutritional Sciences: From Fundamentals to Food, ...
Health & Nutrition
ISBN:9781337486415
Author:McGuire
Publisher:Cengage
Lifetime Physical Fitness & Wellness
Health & Nutrition
ISBN:9781337677509
Author:HOEGER
Publisher:Cengage
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
KINE 2310-Chapter 4: Philosophy of Physical Activity; Author: HBU Online Course Development;https://www.youtube.com/watch?v=8Ky6t3nvP_4;License: Standard youtube license