Biology: Life on Earth Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)
11th Edition
ISBN: 9780134153742
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: PEARSON
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Chapter 13, Problem 2AC
Summary Introduction
To review:
The severity of cystic fibrosis (CF) symptoms in case of different allelic combinations in heterozygotes.
Introduction:
CF is an autosomal recessive genetic disorder which is caused by a defect in the gene coding for the CF transmembrane conductance regulator (CFTR) protein. A defective CFTR protein leads to the body secretions like digestive substances, sweat and mucous becoming thick and blocking the ducts resulting in multiple organ failure and ultimately death.
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Phenylketonuria (PKU) is an inherited disease caused by a recessive allele. Individuals with PKU have two recessive alleles and have very low levels of an enzyme that is needed to properly break down proteins. If a woman and her husband are both carriers and have three children, what is the probability of each of the following? Show your math. (Hint: You can represent your probabilities as fractions or decimals, but probabilities are always between 0 and 1)
a. All three children are of normal phenotype.
b. One or more of the three children have the disease.
c.All three children have the disease.
In humans the allele coding for normal metabolism of the amino acid phenylalanine (P) is dominant over the recessive autosomal allele (p) that causes the disease phenylketonuria, or PKU. Without treatment, this disease is characterized by brain damage due to the failure of the gene to code correctly for the enzyme phenylalanine hydroxylase. If a man marries a woman and both are heterozygous for hemophilia and heterozygous for PKU, what is the chance that they will have a child afflicted by both diseases? Your response MUST include:(a): list the traits involved (example: Color: Blue- B (dominate) Green - b (recessive) -Do not use this example as this is not part of the problem(b): identify if its a monohybrid or dihybrid cross and why (use prompt above) (c): create a punnet square that represents the problem above
In humans, the genetic disease cystic fibrosis is caused by a recessive allele (a). The normal (healthy) allele is dominant (A).
What is the genotype of someone who has cystic fibrosis?
What are the two different genotypes that a healthy person could have?
If two people were both heterozygous for the cystic fibrosis gene, what fraction of their children would be likely to have this disease? Hint: Draw a Punnett square to figure it out.
Chapter 13 Solutions
Biology: Life on Earth Plus Mastering Biology with Pearson eText -- Access Card Package (11th Edition)
Ch. 13 - 1. The molecule that carries the genetic...Ch. 13 - 2. Which of the following is not true of...Ch. 13 - 3. A stop codon
a. signals the end of protein...Ch. 13 - Prob. 4MCCh. 13 - Epigenetic modification of gene expression a....Ch. 13 - Prob. 1FTBCh. 13 - The three types of RNA that are essential for...Ch. 13 - 3. The genetic code uses______ (how many?) bases...Ch. 13 - The enzyme_______ synthesizes RNA from the...Ch. 13 - Prob. 5FTB
Ch. 13 - Prob. 6FTBCh. 13 - How does RNA differ from DNA?Ch. 13 - Prob. 2RQCh. 13 - Define the following terms: genetic code, codon,...Ch. 13 - 4. How is mRNA formed from a eukaryotic gene?
Ch. 13 - 5. Diagram and describe protein synthesis.
Ch. 13 - 6. Explain how complementary base pairing is...Ch. 13 - 7. Describe the principal mechanisms of regulating...Ch. 13 - Define mutation. Describe four different effects...Ch. 13 - Many years ago, some researchers reported that...Ch. 13 - Prob. 2AC
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