BIOLOGY (LL)
5th Edition
ISBN: 9781264115495
Author: BROOKER
Publisher: MCG
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Textbook Question
Chapter 13, Problem 7TY
With regard to miRNAs and siRNAs, which of the following statements is (are) correct?
- a. miRNAs are transcribed from endogenous genes.
- b. miRNAs are usually a perfect match to an mRNA.
- c. siRNAs are transcribed from endogenous genes.
- d. siRNAs cause mRNA degradation.
- e. both a and d
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Check out a sample textbook solutionStudents have asked these similar questions
Arrange the statements in their proper order by writing the corresponding letter
(e.g. A) for each statement in the space provided below.
A. The single-stranded RNA would complement the target RNA.
B. Gene expression is inactivated once the mRNA is no longer accessible for
translation.
C. The risk-induced silencing complex which is composed of RNA and protein
subunits is formed.
D. Double-stranded, non-coding RNA is cleaved by Dicer.
E. The mRNA can be cleaved or remain bound by the RISC.
1.
2.
3.
4.
5.
Alternative RNA splicing
a. is a mechanism for increasing the rate of transcription.
b. can allow the production of proteins of different sizes from a gene.
C. can allow the production of similar proteins from different RNAS.
d. increases the rate of transcription.
e. is due to the presence or absence of particular snRNAs.
Differential RNA splicing may result in:
a. A shift in the ratio of mRNA produced from two neighboring genes
b. Inversion of exons in the mature mRNA
c. Production of the same protein from two different genes
d. Production of two different proteins with different properties from a single gene
Chapter 13 Solutions
BIOLOGY (LL)
Ch. 13.1 - Prob. 1CCCh. 13.2 - Prob. 1CCCh. 13.3 - Prob. 1EQCh. 13.3 - Prob. 2EQCh. 13.3 - Prob. 3EQCh. 13.3 - Effects of Non-coding RNAs on Translation and mRNA...Ch. 13.4 - Non-coding RNAs and Protein Sorting Core Skill:...Ch. 13.5 - Core Skill: Modeling The goal of this modeling...Ch. 13 - Prob. 1TYCh. 13 - Prob. 2TY
Ch. 13 - Prob. 3TYCh. 13 - Prob. 4TYCh. 13 - Prob. 5TYCh. 13 - Prob. 6TYCh. 13 - With regard to miRNAs and siRNAs, which of the...Ch. 13 - Cas1 and Cas2 proteins play a role during which of...Ch. 13 - Which of the following components bind to...Ch. 13 - Abnormalities in the expression of ncRNAs are...Ch. 13 - An ncRNA may have one or more of the following...Ch. 13 - What is RNA interference (RNAi)? Explain how the...Ch. 13 - Prob. 3CQCh. 13 - Prob. 1COQCh. 13 - Go to the PubMed website and search for non-coding...
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- For each statement about gene expression mechanisms, choose the correct end to the sentence. For each gene, the template strand for transcription is determined by…. The direction of translation is determined by…… The tissue-specificity of protein production is determined by…. choices: a. location of the start codon b. location of the promoter c. direction of polymerization by RNA polymerase d. none of these e. direction of movement of ribosomes f. overall orientation of the chromosomearrow_forwardA strain of bacteria possesses a temperature-sensitive mutation in the gene that encodes the rho subunit. At high temperatures, rho is not functional. When these bacteria are raised at elevated temperatures, which of the following effects would you expect to see? Explain your reasoning for accepting or rejecting each of these five options. a. Transcription does not take place. b. All RNA molecules are shorter than normal. c. All RNA molecules are longer than normal. d. Some RNA molecules are longer than normal. e. RNA is copied from both DNA strands.arrow_forwardWhich of the following is NOT true of miRNAs? A. Pri-miRNAs are processed by Drosha in the nucleus to form pre-miRNAs which are cleaved by dicer in the cytoplasm to generate a miRNA. B. miRNAs always lead to the degradation of their mRNA targets. C. miRNAs can be encoded within the vertebrate genome within introns and within intergenic regions. D. miRNAs can generally target more than one mRNAarrow_forward
- Provide the SIGNIFICANT differences between the following: 1. Regulation AFTER transcription mRNA processing miRNAs a. b. 2. Types of Genes Facultative Constitutive a. b.arrow_forwardIf an MRNA is alternatively spliced, then different introns are removed from a pre-MRNA, producing transcripts that will potentially encode proteins with different primary structures. I. the MRNA is found in a bacterial cell. II. transcription and translation of the MRNA will occur simultaneously. the alternative splicing happened in the cytoplasm. IV. Ay different exons from a pre-mRNA will be spliced together. V. the different MRNAS will all have poly-A tails. VI.arrow_forwardChanges in a cell that affect micro RNAs lead to cancer because miRNAs... a. help a cell to maintain a tight control on protein levels in a cell. b. decrease the level of a specific protein. c. increase the level of a specific protein. d. prevent the Warburg effect.arrow_forward
- According to the adaptor hypothesis, is each the following statementstrue or false?A. The sequence of an anticodon in a tRNA directly recognizes acodon sequence in mRNA, with some allowance for wobble.B. The amino acid attached to the tRNA directly recognizes acodon sequence in mRNA.C. The amino acid attached to the tRNA affects the binding of thetRNA to a codon sequence in mRNA.arrow_forwardWhich of the following statements about pre-mRNA splicing is FALSE? a. Splicing of an intron requires consensus sequences at the splice donor, the splice acceptor and the branch point of the intron. b. The spliceosome contains proteins and RNA molecules. c. Some snRNAs base pair with splice consensus sequences on the primary transcript. d. Splicing happens before the export of the mRNA to the cytoplasm. e. Splicing happens in the cytoplasm, when spliceosomes move down the pre-mRNA in front of ribosomes.arrow_forwardWhich of the following is true of CpG islands? a. They are methylated near promoters of actively transcribed genes. b. They are unmethylated near promoters of actively transcribed genes. c. Acetylation of CpG islands leads to repression of transcription. d. CpG islands code for RNA molecules that activate transcription.arrow_forward
- Transcriptional repressor proteins (e.g., lac repressor), antisense RNA, and feedback inhibition are three different mechanisms that turn off the expression of genes and gene products. Which of these three mechanisms will be most effective in each of the following situations? A. Shutting down the synthesis of a polypeptide B. Shutting down the synthesis of mRNA C. Shutting off the function of a protein For your answers to parts A–C that list more than one mechanism, which mechanism will be the fastest or the most efficient?arrow_forwardA geneticist induces a mutation in eukaryote cells. The mutation results in an inability to form the poly(A) tail during processing of pre-mRNA. What does this mean for the mature mRNA and what will be the effect on these cells? Possible Answers: A. The mRNA will be spliced, but will not have a 5' cap. B. The mRNA will likely be degraded. C. The mRNA will not be cleaved. D. The mRNA will have too many Gs and Cs.arrow_forwardProtein levels and mRNA levels for a particualr gene don’t always match. For example, the GCN4 gene in yeast is always producing mRNA, but the Gcn4 protein is only made when the cells are starved. A. what is one mechanism by which changes in mRNA levels are not always matched by changes in the protein product of that mRNA?arrow_forward
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